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Mechanical power curve measured in the wake of pied flycatchers indicates modulation of parasite power across flight speeds

How aerodynamic power required for animal flight varies with flight speed determines optimal speeds during foraging and migratory flight. Despite its relevance, aerodynamic power provides an elusive quantity to measure directly in animal flight. Here, we determine the aerodynamic power from wake velocity fields, measured using tomographical particle image velocimetry, of pied flycatchers flying fr

A critical evaluation of wet biomarkers for huntington's disease : Current status and ways forward

There is an unmet clinical need for objective biomarkers to monitor disease progression and treatment response in Huntington's disease (HD). The aim of this review is, therefore, to provide practical advice for biomarker discovery and to summarise studies on biofluid markers for HD. A PubMed search was performed to review literature with regard to candidate saliva, urine, blood and cerebrospinal f

TEMPO-oxidised cellulose nanofibrils; Probing the mechanisms of gelation : Via small angle X-ray scattering

The structure of dispersions of TEMPO-oxidised cellulose nanofibrils (OCNF), at various concentrations, in water and in NaCl aqueous solutions, was probed using small angle X-ray scattering (SAXS). OCNF are modelled as rod-like particles with an elliptical cross-section of 10 nm and a length greater than 100 nm. As OCNF concentration increases above 1.5 wt%, repulsive interactions between fibrils

Kinetic analysis of amyloid formation

The formation of amyloid fibrils is a central phenomenon in the progressive pathology of many neurodegenerative diseases, as well as in the fabrication of functional materials. Several different molecular processes acting in concert are responsible for the formation of amyloid fibrils from monomeric protein in solution. Here, we describe a method to determine which microscopic processes drive the

EFAS Score — Multilingual development and validation of a patient-reported outcome measure (PROM) by the score committee of the European Foot and Ankle Society (EFAS)

Background: A scientifically sound validated foot and ankle specific score validated ab initio for different languages is missing. The aim of a project of the European Foot and Ankle Society (EFAS) was to develop, validate, and publish a new score(the EFAS-Score) for different European languages. Methods: The EFAS Score was developed and validated in three stages: (1) item (question) identificatio

Global metawebs of spider predation highlight consequences of land-use change for terrestrial predator–prey networks

Land-Use Change and Terrestrial Predator–Prey Networks Land-use change, here defined as the conversion of one land-use type into another (e.g., forest to arable land), affects biodiversity and biotic interactions worldwide (Sala et al., 2000). Although there has been large regional variation in the extent of agricultural expansion and abandonment in Europe in the past 50 years (Rabbinge and van Di

Quality of work in prostitution and sex work. Introduction to the special section

Increasingly, prostitution and other activities in the sex industries have been conceptualised as forms of labour, or at least as income-generating activities. As labour, these activities are exposed to particular risks with respect to health, working conditions, exploitation and stigmatisation. However, research on the actual conditions and circumstances existing in these markets, remains limited

The Effect of Family History of Diabetes and Middle Eastern Background on Abdominal Obesity is Modified by Gender: A Population based Cross-Sectional Study

Background: Abdominal obesity is on the increase worldwide and ethnic minority groups are at high risk. However, studies of the underlying causes are scarce. The aims of this study were to investigate the prevalence of abdominal obesity and to identify metabolic, lifestyle and socio-demographic risk factors associated with abdominal obesity in male and female residents of Malmö, a city in southern

Quantitative Imaging-Biomarker in Prostate Cancer. Validation of Automated Bone Scan Index in the Context of Radiographic Disease Progression in Metastatic Castration Resistant Prostate Cancer

Background: Metastatic castration resistant prostate cancer (mCRPC) is a bone dominant lethal disease. Progression in bone scan of mCRPC disease is assessed with the Prostate Cancer Working Group (PCWG) two and three criteria, which relies on the appearance of two or more new lesions. There is an unmet need for a quantitative assessment that can build on the current progression criteria. This thes

Acoustic impedance matched buffers enable separation of bacteria from blood cells at high cell concentrations

Sepsis is a common and often deadly systemic response to an infection, usually caused by bacteria. The gold standard for finding the causing pathogen in a blood sample is blood culture, which may take hours to days. Shortening the time to diagnosis would significantly reduce mortality. To replace the time-consuming blood culture we are developing a method to directly separate bacteria from red and

Association between post-diagnostic use of cholera vaccine and risk of death in prostate cancer patients

Recent evidence suggests that cholera toxin might have multiple functions regarding the ability to regulate the immune system. However, it is unknown whether subsequent administration of cholera vaccine might affect the mortality rate in patients with prostate cancer. Here we report that patients in Sweden, who were diagnosed with prostate cancer between July 2005 and December 2014 and used choler

Hydrophilization of bixin by lipase-catalyzed transesterification with sorbitol

Bixin is one of the most used yellow-orange food colorants in the food industry. The polyene chain of bixin makes it highly hydrophobic and less suitable for water-based food formulations. Lipase-catalyzed reactions of bixin with sorbitol were studied to synthesize a new derivative of bixin with potential hydrophilic properties. Interestingly, we show that the lipase-catalyzed reaction of bixin le

Riverine dissolved organic carbon in Rukarara River Watershed, Rwanda

Dissolved organic carbon (DOC) loading is rarely estimated in tropical watersheds. This study quantifies DOC loading in the Rukarara River Watershed (RRW), a Rwandan tropical forest and agricultural watershed, and evaluates its relationship with hydrological factors, land use and land cover (LULC), and topography to better understand the impact of stream DOC export on watershed carbon budgets. The

Emissions from thaw ponds largely offset the carbon sink of northern permafrost wetlands

Northern regions have received considerable attention not only because the effects of climate change are amplified at high latitudes but also because this region holds vast amounts of carbon (C) stored in permafrost. These carbon stocks are vulnerable to warming temperatures and increased permafrost thaw and the breakdown and release of soil C in the form of carbon dioxide (CO2) and methane (CH4).

Experimental evidence that stripes do not cool zebras

There are as many as 18 theories for the possible functions of the stripes of zebras, one of which is to cool the animal. We performed field experiments and thermographic measurements to investigate whether thermoregulation might work for zebra-striped bodies. A zebra body was modelled by water-filled metal barrels covered with horse, cattle and zebra hides and with various black, white, grey and