Gastrointestinal stromal tumors (GISTs), the most common mesenchymal tumors of the digestive tract, are believed to arise from the interstitial cells of Cajal. GISTs are characterized by mutations in the proto-oncogene KIT that lead to constitutive activation of its tyrosine kinase activity. The tyrosine kinase inhibitor STI571, active against the BCR-ABL fusion protein in chronic myeloid leukemia

Popular Abstract in Swedish Påverkan av faktor V Leiden-mutationen på risk för utveckling av neovaskulära komplikationer efter centralvenstrombos studerades. Hos patienter med mutationen var risken nästan tre gånger högre att utveckla neovaskulära komplikationer än hos patienter utan mutationen. Synnervssvullnad , som nyligen har presenterats som en indikator på god prognos vid centralvenstrombosThe influence of the factor V Leiden mutation on the development of neovascular complications in central retinal vein occlusion was studied. The presence of the mutation was found to enhance the risk of developing neovascular complications almost threefold compared to in patients without the mutation. Optic nerve head swelling, which recently has been presented as an indicator of good prognosis i

To investigate how the relation between the control time and the total amount of water varies with the water application rate at manual fire fighting operations, six different experimental fire test series were studied. In spite of being quite different, the experiments prove to give similar results. Plotting the total volume of water required against the application rate, gives a diagram in the s

A measurement of direct photons in p+p collisions at root s=200 GeV is presented. A photon excess above background from pi(0)->gamma+gamma, eta ->gamma+gamma and other decays is observed in the transverse momentum range 5.5 < p(T)< 7 GeV/c. The result is compared to a next-to-leading-order perturbative QCD calculation. Within errors, good agreement is found between the QCD calculation and the meas

This paper presents a decision theory which allows subjects to account for the uncertainties of their probability estimates. This is accomplished by modelling beliefs about states of nature by means of a class of probability measures. In order to represent uncertainties of those beliefs a measure of epistemic reliability is introduced. The suggested decision theory is evaluated in the light of emp

The goal of the study is to cast light on the psychological factors behind the participation in nature conservation projects aiming to promote biodiversity. Two projects, wetland restoration and forest preservation, are examined through the framework of the VBN (Value-Belief-Norm) theory. A survey was conducted among 120 farmers and 160 forest owners in southern Sweden. Results did not support the

On Sufi gatherings in London and the impact of a visiting shaykh.

Females of the European pine sawfly, Neodiprion sertifer (Geoffr) (Hymenoptera: Diprionidae), were released and observed inside and outside (=control) of areas treated with their sex pheromone for the purpose of mating disruption. In 1992 and 1993, respectively, 0 and 2.5% of the females were observed mating in the pheromone treated area during the first day compared with 28 and 26% in the control

The effect of the spatial distribution of hydrophobic surface residues on the adsorption of a weakly hydrophobic polymer to proteins has been examined using a coarse-grain model solved by Monte Carlo simulations. A given number of surface sites were distributed randomly on the protein surface subjected to a distance constraint. Five protein classes for which the minimum distance between the sites

The inclusive production of D*+/-(2010) mesons in deep-inelastic scattering is studied with the HI detector at HERA. In the kinematic region 1 < Q(2) < 100 GeV2 and 0.05 < y < 0.7 an e(+) p cross section for inclusive D*+/- meson production of 8.50 +/- 0.42(stat.)(-100)(+1.21)(syst.) nb is measured in the visible range p(tD*) > 1.5 GeV and eta(D*) < 1.5. Single and double differential inclusive D*

New, precise abundance data for a large number of elements in a growingsample of extremely metal-poor stars are accumulating from the new 8-mtelescopes. Combined with theoretical models, these results advance ourunderstanding of the first generations of stars, whose nucleosynthesisproducts are fossilised in the oldest stars we see today and thus giveclues to the earliest phases of evolution in the