Background: Total plasma homocysteine (tHcy) concentration is elevated in patients with psychogeriatric disease. There are many different determinants of plasma tHcy concentration, including the presence of vascular disease. Method: We investigated plasma tHcy levels in several different subgroups of vascular disease and also the relation between plasma tHcy and renal function in patients with psy

AIM: The aim of this paper was to define the incidence of disease progression of the contralateral internal carotid artery (CICA) in patients undergoing carotid endarterectomy (CEA) and to identify factors influencing disease progression. METHODS: Patients from our primary catchment area that had undergone CEA between 2002 and 2005 were included. The study cohort was divided in four groups based

Knowledge of the natural emissions of mercury in the Mediterranean basin, which has large cinnabar anomalies, has particular weight as these deposits could be an important source of atmospheric mercury. Data on the degassing rate of mercury from soils sampled both in mineralized areas (Mt. Amiata, Italy and Almaden, Spain) and rural areas are reported. Measurements were carried out 'in situ' using

Here we explore two new tree-ring parameters, derivedfrom measurements of wood density and blue intensity(BI). The new proxies show an increase in the interannualsummer temperature signal compared to establishedproxies, and present the potential to improve long-term performance.At high latitudes, where tree growth is mainlylimited by low temperatures, radiodensitometric measurementsof wood density

Subcellular localization is an important protein property, which is related to function, interactions and other features. As experimental determination of the localization can be tedious, especially for large numbers of proteins, a number of prediction tools have been developed. We developed the PROlocalizer service that integrates 11 individual methods to predict altogether 12 localizations for a

Hemophilia patients with inhibitors against FVIII/FIX present with a major challenge in the clinical practice. In the 1970s such patients were treated in association with emergency situations and essential surgery using huge amounts of FVIII/FIX concentrates often preceded by extracorporal adsorption of antibodies against FVIII/FIX. However, moderate to mild bleedings were not effectively treated.

Start-up companies and young firms are driving forces of innovation and regional economic development. They are acknowledged to play a crucial role as innovation agents, particularly, in knowledge-based industries. Most scholars agree that young firms and academic spin-offs innovate more radically, drawing on the knowledge generated in universities and research organisations. It is often assumed t

Melatonin is a powerful antioxidant and a synchronizer of many physiological processes. Alteration in melatonin signaling has been reported in a broad range of diseases, but little is known about the genetic variability of this pathway in humans. Here, we sequenced all the genes of the melatonin pathway -AA-NAT, ASMT, MTNR1A, MTNR1B and GPR50 - in 321 individuals from Sweden including 101 patients

BACKGROUND Surgical site infections (SSIs) after dermatologic surgery cause pain, prolong healing, result in unaesthetic complications, and lead to excessive use of antibiotics. The pathogenesis of wound infections is complex and is dependent on bacterial load and diversity, among several factors. OBJECTIVE To investigate bacterial dynamics at dermatosurgical sites at different time intervals and

A short overview of eta and eta' decays is given with an emphasis on what can be learned for the strong interaction from them. The talk consists of a short introduction to Chiral Perturbation Theory, a discussion of eta -> 3 pi beyond p(4) and some of the physics involved in eta' -> eta pi pi, 3 pi as well as an overview of anomalous processes.

Starting from the German pitch peak timing categories and their communicative functions, it is asked how these functions would be expressed in South Swedish. The aim is to get a first impression as regards potentially relevant prosodic parameters associated with the expression of expected vs. unexpected information in South Swedish. For that, an interactive manipulation experiment is conducted, wh

High-resolution, angle-resolved resonant Auger electron spectra of the NO molecule in the regions of both N and O 1s --> 2pi core electron excitations are presented. A large number of vibrational final states are resolved due to high energy resolution. Calculations based on lifetime vibrational interference (LVI) theory neglecting interference between different electronic intermediate states and b

Due to its unique ability to split water, Photosystem II (PSII) is easily accessible to oxidative damage. Photoinhibited PSII centres diffuse laterally from the grana core region of the thylakoid membrane to the stroma lamellae in order to allow replacement of damaged proteins and cofactors. The 'new born' PSII centres in this region are characterized by the absence of the water splitting capacity

Abstract in Undetermined Kardiovaskulära sjukdomar med debut i yngre åldrar är ofta ärftliga. Molekylärgenetisk diagnostik kan förbättra möjligheten till presymtomatisk diagnostik i drabbade familjer. Förbättrad presymtomatisk diagnostik kan rikta förebyggande sjukvårdsåtgärder mot dem som har högst risk att insjukna, och kan därmed vara kostnadseffektiv.

The aim of this study was to evaluate the relationship between respiratory symptoms, lung function and inflammatory markers in 'healthy' smokers. The study population was recruited from an epidemiological study with subjects of the same age, 60 years. Only smokers who considered themselves healthy (n=58) and a random sample of never-smokers (n=34) were investigated. All subjects underwent lung fun