Crosslinking of small heat-shock proteins (sHsps) by tissue transglutaminase (tTG) is enhanced by stress and under pathological conditions. We here used hexapeptide probes to determine the amine donor (K) and acceptor (Q) sites for tTG in Hsp20. Mass spectrometric peptide mass fingerprinting and peptide fragmentation established that Q(31) and the C-terminal K-162 are involved in inter- and intram

Chlordane was used as an insecticide for half a century until its withdrawal from the world market in 1997. Trans- and cis-chlordane (TC, CC) are racemic in the technical product, but undergo enantio selective degradation in soil to leave nonracemic residues. In most cases, the (+) enantiomer of TC and the (-) enantiomer of CC are depleted, leading to enantiomer fractions, EF = (+)/[(+) + (-)], th

This study of 36 rats with rat colon adenocarcinoma transplants was carried out to investigate the efficacy of a new method of whole blood immunoadsorption (WBIA) in removing biotinylated monoclonal antibodies (MAbs) directly from unseparated blood, in order to increase 'the tumor/normal-tissue uptake ratio', as compared with extracorporeal immunoadsorption (ECIA) of antibodies from plasma. Compar

The structurally related group II pyridoxal phosphate (PLP)dependent amino acid decarboxylases glutamic acid decarboxylase (GAD), aromatic L-amino acid decarboxylase (AADC), and histidine decarboxylase (HDC) are known autoantigens in endocrine disorders. We report, for the first time, the prevalence of serum autoantibody reactivity against cysteine sulfinic acid decarboxylase (CSAD), an enzyme tha

Today the main optimization parameter of digital filters is the filter order. By the aid of two implemented filters we will show that both power and speed can be enhanced if the optimization effort is made on reducing the filter coefficient lengths rather than minimizing the order. Both filters have been designed from the same specification, one as a standard minimum order filter, the other as a f

A conscious therapeutic approach was used combining methods in physiotherapy with psychological awareness to re-educate nine transfemoral amputees during 10 months in outdoor environments. All were rehabilitated trauma or tumour cases, mean age 33 years, and had worn their prostheses for more than 18 months. The method aimed at integrating the prosthesis in normal movements and increasing body awa

35 episodes of septicemia in 33 patients occurred among 269 consecutive patients with granulocytopenia (granulocyte cell count less than or equal to 0.5 x 10(9)/l) during the 7-year period 1982-1988. 59% of isolated bacteria were Gram-positive (Staphylococcus aureus, Staph. epidermidis, Streptococcus species and Pneumococcus) and 41% Gram-negative (Pseudomonas aeruginosa, Escherichia coli, Klebsie

Disruption of the ZWF1 gene encoding glucose-6-phosphate dehydrogenase (G6PDH) has been shown to reduce the xylitol yield and the xylose consumption in the xylose-utilizing recombinant Saccharomyces cerevisiae strain TMB3255. In the present investigation we have studied the influence of different production levels of G6PDH on xylose fermentation. We used a synthetic promoter library and the copper

We suggest an approach for transport through finite systems based on the Liouville equation. By working in a basis of many-particle states for the finite system, Coulomb interactions are taken fully into account and correlated transitions by up to two different contact states are included. This latter extends standard rate equation models by including level-broadening effects. The main result of t

Abstract in Spanish Inger Enkvist, catedrática de español de la Universidad de Lund, Suecia, trabajó durante tres años en un proyecto de investigación junto con Ángel Sahuquillo, de la Universidad de Sodertorn, también en Suecia, en un proyecto titulado "Identidad e ideología en la literatura hispánica: un estudio basado en la obra de Juan Goytisolo". El presente artículo demuestra que el resultad

Through alterations primarily in the penicillin-binding proteins, a non-beta-lactamase-mediated resistance to beta-lactams has evolved in Haemophilus influenzae. The virulence of these chromosomally changed strains has been questioned. To ascertain whether these alterations involve a reduction in virulence of H. influenzae and whether they could be advantageous for the bacterium during amoxicillin

The number of local and regional-scale water management failures appears steadily to increase despite an apparently higher level of engineering solutions at hand. The objective of this paper is to examine the challenges the existing education system needs to meet in order to produce water engineers capable of responding to the complexity of contemporary and future water problems in relation to soc