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A Case Study Evaluation of the Guideline-Supported QUPER Model for Elicitation of Quality Requirements
[Context & motivation] For market-driven software product developing organizations operating on a competitive open market, it is important to plan the product’s releases so that they can reach the market as early as possible with a competitive level of quality compared to its competitors' products. Hence, quality requirements can be seen as a key competitive advantage. The QUPER model was deve
Tuning the performance of an artificial protein motor
The Tumbleweed (TW) is a concept for an artificial, tri-pedal, protein-based motor designed to move unidirectionally along a linear track by a diffusive tumbling motion. Artificial motors offer the unique opportunity to explore how motor performance depends on design details in a way that is open to experimental investigation. Prior studies have shown that TW's ability to complete many successive
Differential activity of c-KIT splice forms is controlled by extracellular peptide insert length.
Understanding receptor activation is important for disease intervention. Activation of the receptor tyrosine kinase c-KIT is involved in numerous diseases including melanoma, mastocytosis, multiple myeloma and gastrointestinal stromal tumors. To better understand the regulation of activation, we studied the two c-KIT isoforms, c-KIT(-) and c-KIT(+) which differ by a tetrapeptide insert GNNK, locat
Psychometric properties of a Swedish version of the Pearlin Mastery Scale in people with mental illness and healthy people.
Background: Mastery refers to the degree to which people perceive that they can control factors that influence their life situation, and has been found important for people's quality of life and well-being. It is thus essential to be able to measure mastery in a valid and reliable way. Aim: This study aimed at using the Rasch measurement model to investigate the psychometric properties of a Swed
Prediction of Significant Prostate Cancer Diagnosed 20 to 30 Years Later With a Single Measure of Prostate-Specific Antigen at or Before Age 50
BACKGROUND: We previously reported that a single prostate-specific antigen (PSA) measured at ages 44-50 was highly predictive of subsequent prostate cancer diagnosis in an unscreened population. Here we report an additional 7 years of follow-up. This provides replication using an independent data set and allows estimates of the association between early PSA and subsequent advanced cancer (clinical
‘And People's Concerns Were Genuine: Why Didn't We Listen More?’: Nationalism, Multiculturalism and Recognition in Europe
The aim of this article is to draw attention to the dangerous, indeed poisonous, nature of the current debates on immigration and multiculturalism in today’s ‘omniphobic’ Europe, plagued not only by a severe economic crisis, but also a more general normative crisis, a ‘crisis of values’ so to speak, which has been consistently overlooked or manipulated by politicians and academics alike, or reduce
"I'm Dr Jekyll and Mr Hyde": Are GPs' antibiotic prescribing patterns contextually dependent? A qualitative focus group study.
Abstract Objective. To explore factors and circumstances contributing to prudent antibiotic prescribing for respiratory tract infections in primary care. Design. Two focus groups representing rural and urban areas. A semi-structured interview guide with open-ended questions and an editing analysis style was used. They were examined to identify meaning units that were sorted into categories in an i
EUCAARI ion spectrometer measurements at 12 European sites - analysis of new particle formation events
We present comprehensive results on continuous atmospheric cluster and particle measurements in the size range similar to 1-42 nm within the European Integrated project on Aerosol Cloud Climate and Air Quality interactions (EUCAARI) project. We focused on characterizing the spatial and temporal variation of new particle formation events and relevant particle formation parameters across Europe. Dif
Democracy on the Margin: Architectural means of appropriation in governmental alteration of space
Who is not adhering to physical activity referrals, and why?
Objective. To analyse patients' self-reported reasons for not adhering to physical activity referrals (PARs). Design and setting. Data on 1358 patients who did not adhere to PARs were collected at 38 primary health care (PHC) centres in Sweden. Intervention. PHC providers issued formal physical activity prescriptions for home-based activities or referrals for facility-based activities. Subjects. O
Tre frågor om diskriminering
Diskrimineringsterminologi förekommer på olika rättsliga nivåer: i internationell rätt, i grundlag och i vanlig nationell lagstiftning. Innebörden och användningen av ”diskriminering” varierar en del mellan olika rättsliga kontexter. Samtidigt vore diskriminering inte föremål för rättslig reglering på någon nivå om det inte betraktades som moraliskt problematiskt. Det rättsliga och det moraliska h
Plastid and nuclear DNA marker data support the recognition of four tetraploid marsh orchids (Dactylorhiza majalis s.l., Orchidaceae) in Britain and Ireland, but require their recircumscription
Relationships among allotetraploid marsh orchids collectively assignable to Dactylorhiza majalis s.l. are exceptionally complex because of multiple origins, secondary hybridization with each other, and with their parental lineages, local adaptation, and genomic reorganization processes, all extending through time and space. We sampled 34 populations from Britain and Ireland in an attempt to simult
A multifractal mass transference principle for Gibbs measures with applications to dynamical Diophantine approximation
Let mu be a Gibbs measure of the doubling map T of the circle. For a mu-generic point x and a given sequence {r(n)} subset of R+, consider the intervals (T-n x - r(n) (mod 1), T-n x + r(n) (mod 1)). In analogy to the classical Dvoretzky covering of the circle, we study the covering properties of this sequence of intervals. This study is closely related to the local entropy function of the Gibbs me
Membrane performance during ultrafiltration of a high-viscosity solution containing hemicelluloses from wheat bran
Hemicelluloses isolated from agricultural residues have the potential to replace fossil-based materials in high-value-added applications, provided that cost-efficient isolation processes are developed. In this study, a feed solution containing hemicelluloses extracted from wheat bran with a particular high viscosity was used to study the performance of ultrafiltration for hemicellulose isolation a
Social background and life-course risks as determinants of social assistance receipt among young adults in Sweden,Norway and Finland
Translation and cultural adaptation of research instruments - guidelines and challenges: an example in FAMCARE-2 for use in Sweden
Background: Assessing and evaluating health care is important, and an abundance of instruments are developed in different languages. Translating existing, validated instruments is demanding and calls for adherence to protocol. Purpose: The purpose of this study was to translate and culturally adapt the FAMCARE-2 scale for use in Sweden. Methods: Traditional back-translation and the decentering sta
Search for new phenomena in events with three charged leptons at root s=7 TeV with the ATLAS detector
A generic search for anomalous production of events with at least three charged leptons is presented. The search uses a pp-collision data sample at a center-of-mass energy of root s = 7 TeV corresponding to 4.6 fb(-1) of integrated luminosity collected in 2011 by the ATLAS detector at the CERN Large Hadron Collider. Events are required to contain at least two electrons or muons, while the third le
Temporal trends in the incidence and prognosis of aortic stenosis: a nationwide study of the Swedish population.
The aging of Western populations is expected to result in increasing occurrence of aortic stenosis (AS), but data are limited. Recent studies have reported declining incidence and mortality for other major heart diseases. We aimed to study temporal trends in the incidence and prognosis for AS in Sweden.
Urban Transport Transitions: Copenhagen, City of Cyclists.
Mobility growth poses considerable challenges to city planners around the world, as it entails problems of congestion, air pollution, and accidents. Many cities have thus sought to increase the share of sustainable transport, and specifically travel by bicycle. However, it appears that measures to foster cycling are often implemented on an ad hoc basis, lacking strategic focus and a more profound