Purpose: To monitor cardiovascular health, in 2022, the American Heart Association (AHA) updated the construct “Life’s Simple 7” (LS7) to “Life’s Essential 8” (LE8). This study aims to analyze the associations and capacity of discrimination of LE8 and LS7 in relation to self-rated health (SRH) and health-related quality of life (HRQoL). Methods: This study from the Swedish CArdioPulmonary bioImage

Context. The star cluster initial mass function is observed to have an inverse power law exponent around 2, yet there is no consensus on what determines this distribution, and why some variation is observed in different galaxies. Furthermore, the cluster formation efficiency (CFE) covers a range of values, particularly when considering different environments. These clusters are often used to empir

Size Exclusion Chromatography (SEC) is a crucial analytical tool employed by Novo Nordisk for the assessment of potential aggregation in active pharmaceutical ingredients (API) derived from peptides and protein biopharmaceuticals. This investigation focuses on SEC analyses conducted under denaturing conditions, utilizing Ultra High-Performance Liquid Chromatography (HULK) adapted columns. Intrigui

The solution of multi-field problems and the numerical implementation by means of the finite element method constitute a sophisticated part of the characterisation of industrial processes. A comprehensive implementation framework for such a system of coupled field equations into a non-linear large strain finite element formulation is provided. The procedure is derived for a micromorphic approach i

The Nordic countries (Denmark, Finland, Iceland, Norway, and Sweden) have effectively kept lower antibiotic-resistant bacterial (ARB) pathogen rates than many other countries. However, in recent years, these five countries have encountered a rise in ARB cases and challenges in treating infections due to the growing prevalence of ARB pathogens. Wastewater-based surveillance (WBS) is a valuable supp

Introduction to the works of American poet Fanny Howe (b. 1940), icluding translations of five poems.

This article investigates the geographies of subprime urbanization, and by extension, the displacement of 2007–08 financial crisis to the Global South. Previous research examined the formative ways that technological innovations enabled mortgages to deterritorialize and circulate on secondary markets. Less is known about how cities with underdeveloped financial systems and housing markets have bee

Current hemophilia B treatment guidelines recommend routine prophylaxis with factor IX (FIX) replacement products, tailored to maintain plasma activity at levels that will prevent bleeds. However, plasma FIX activity may not be the primary determinant or best indicator of hemostatic efficacy due to its extravascular distribution. FIX replacement therapy has evolved to include extended half-life (E

AimTo explore perceptions of annual surveillance with magnetic resonance imaging and perceptions of care during the examination among women with a hereditary risk of breast cancer.DesignPhenomenography.MethodsFourteen face-to-face interviews using a semi-structured interview guide were conducted among women undergoing surveillance in the southern region of Sweden. A seven-step phenomenographic ana

It has been shown previously that the immune system plays a role in implantation and embryo development. The objective was therefore to evaluate cytokine levels and Th1/Th2 ratio in women with recurrent implantation failure in this nested case-control study. Women with no implantation after ≥ 3 embryo transfers were included in the recurrent implantation failure group (n = 29) and were compared wi

G protein-coupled receptor 30 (GPR30), also named G protein-coupled estrogen receptor (GPER), and the β1-adrenergic receptor (β1AR) are G protein-coupled receptors (GPCR) that are implicated in breast cancer progression. Both receptors contain PSD-95/Discs-large/ZO-1 homology (PDZ) motifs in their C-terminal tails through which they interact in the plasma membrane with membrane-associated guanylat

De svenska kontorsmarknaderna i Stockholm, Göteborg och Malmö har sett ökade vakansgrader under de senaste åren. En viktig faktor bakom detta är anställdas preferenser efter Covid-19-pandemin. Även om närvaron på kontoren har börjat öka igen, har utnyttjandegraden sjunkit i Sverige, och hyresgäster prioriterar nu sin hyresportfölj och ytoptimering för att spara kostnader. Vakans i kontorsbyggnaderThe Swedish office markets especially in the three major cities Stockholm, Gothenburg, and Malmö have experienced increased vacancy rates in recent years. One key factor behind this is employees' preferences post the Covid-19 pandemic. Despite a gradual return to offices, the utilization rate has decreased in Sweden, prompting tenants to prioritize their lease portfolios and space optimization

Inom fastighetsbildning är lämplighetskravet ett centralt begrepp som lägger grunden för alla fastighetsbildningar och fastighetsregleringar som genomförs. Grundpelarna som bygger upp lämplighetsprövningen är belägenhet, omfång, och övriga förutsättningar. Trots detta finns det förhållandevis lite fasta gränser eller riktmärken att hålla sig till, vilket delvis är meningen, men det kan göra lämpliA property’s suitability is a central part of the Swedish Property Formation Act. It states that any creation or reformation of property must be suitable in regards to range, situation and other circumstances. Despite this, the actual requirements as to what is suitable are very vague, which in part is on purpose to account for changing politics and research. This master’s thesis aims to clarify t

Georg Pauli belonged to a group of artists known as the Opponents, due to their opposition of the way art education, exhibitions, and allocation of grants was managed by the The Royal Swedish Academy of Fine Arts (Kungliga Akademien för de fria konsterna). Their oppositional work resulted in the formation of the Arts Association (Konst¬närs¬förbundet) in 1886. In a series of books and articles, in

Varmt, varmare, varmast i mätningshistorien. Året 2023 blev det varmaste som någonsin har uppmätts på jorden. Denna värmerekordsättande utveckling beskrivs samtidigt som det nya vanliga, vilket innebär att kommande byggnader måste utformas med hänsyn till denna nya extremvädernormalitet. Utvecklingen medför vidare ökande behov av svalka, vilka behöver tillgodoses åtminstone delvis på andra sätt änWarm, warmer, warmest average temperatures on record. The year of 2023 was the hottest ever recorded on Earth. This heat record breaking development is described as “the new normal”, which means that future buildings must be designed with this new extreme weather normality in mind. The rising heat brings increased demands for space cooling, which must be at least partially met in other ways than t

This qualitative study aims to investigate the meaning of the smartphone for young people as well as the way young people experience their parents and the staff at schools relating to them using their smartphones. It also investigates young peoples thoughts about restrictions made by their parents and the staff at school and if or in what ways the restrictions may affect the relationship between a

Cancer invasion and metastasis are known to be potentiated by the expression of aquaporins (AQPs). Likewise, the expression levels of AQPs have been shown to be prognostic for survival in patients and have a role in tumor growth, edema, angiogenesis, and tumor cell migration. Thus, AQPs are key players in cancer biology and potential targets for drug development. Here, we present the single-partic

Obligately multicellular organisms, where cells can only reproduce as part of the group, have evolved multiple times across the tree of life. Obligate multicellularity has only evolved when clonal groups form by cell division, rather than by cells aggregating, as clonality prevents internal conflict. Yet obligately multicellular organisms still vary greatly in 'multicellular complexity' (the numbe

The thesis presented here delves into why dwell time delays for commuter trains occur, with a specific focus on the impact of boarding and alighting passengers. The overarching aim is to develop knowledge of how time delays arise to identify and describe potential ways in which dwell time delays can be reduced. In addition to this, a secondary aim is to identify how dwell times can be studied on a