BACKGROUND: The effect of risk-reducing salpingo-oophorectomy (RRSO) on breast cancer risk for BRCA1 and BRCA2 mutation carriers is uncertain. Retrospective analyses have suggested a protective effect but may be substantially biased. Prospective studies have had limited power, particularly for BRCA2 mutation carriers. Further, previous studies have not considered the effect of RRSO in the context

The compelling images and promises attached to autonomous drive vehicles can easily create an impression that one can speak of a radical distinction between a self-driving future and a manual-driving present. Yet today’s drivers can already refer to their everyday driving as being experienced as though on ‘auto-pilot’, in which they are able to drive their cars while lost in things such as daydrea

Om mordet på Caesar.

Copyright law reflects a balance between the competing interests of protection and access. It is often held that this balance has been disturbed by recent technological and related legal developments. This article describes and compares two vehicles to enhance access to information in the online environment, while also taking into account the interest of protection: (i) the introduction of (broade

The ever increasing use of the Internet and of digitisation technologies have opened up new possibilities for distributing and accessing creative content online, including for cultural heritage institutions. However, the digitisation and dissemination of a substantial proportion of the collections held by European cultural institutions may be considerably hindered due to high transaction costs rel

Joint Species Distribution Modelling (JSDM) is becoming an increasingly popular statistical method for analysing data in community ecology. Hierarchical Modelling of Species Communities (HMSC) is a general and flexible framework for fitting JSDMs. HMSC allows the integration of community ecology data with data on environmental covariates, species traits, phylogenetic relationships and the spatio-t

The presence of serotonin (5-hydroxytryptamine [5-HT]) in pancreatic endocrine cells is well established. Nevertheless, recent advances are only now unraveling the signaling network involving 5-HT that partly regulates the release of hormones emanating from the islets of Langerhans. It is widely accepted that failure of the pancreatic β-cell to release sufficient amounts of insulin is the main cul

The ability to store and mobilize energy is fundamental for physiologic function. Most excess energy is stored in adipose tissue as triglycerides, which is released as free fatty acids when needed through cellular processes tightly regulated by insulin. Intact adipose cell function is essential to regulate whole-body glucose and lipid metabolism. Several studies have focused on the metabolic impac

A case‐referent study on soft tissue sarcomas (STS) was conducted, to see if previous findings regarding an association between exposure to phenoxyacetic acids or chlorophenols and this tumor type could be reproduced. Fifty‐five male STS patients were thereby compared with 220 living and 110 dead population‐based referents. Furthermore, another referent group consisting of 190 patients with anothe