Sökresultat

Filtyp

Din sökning på "*" gav 529743 sökträffar

Promoting the Scientist-practitioner Mindset in Clinical Training

While the scientist-practitioner model of training has enjoyed wide-spread appeal, difficulties in implementing the model have continued since its inception. Despite these difficulites, we remain advocates of the model and believe responsibility for inculcating a scientist-practitioner mindset rests with both training programs and trainees themselves. Thus, we offer several suggestions for both tr

Deglutition in elderly patients with dementia: findings of videofluorographic evaluation and impact on staging and management

Oral and pharyngeal function in 131 institutionalized elderly patients with advanced dementia was evaluated by means of videofluoroscopic deglutition examination (VDE). Findings were normal in only nine (7%) patients. Oral-stage dysfunction was observed in 93 (71%) patients, pharyngeal dysfunction in 56 (43%), and pharyngoesophageal-segment abnormalities in 43 (33%). Multiple-stage dysfunction was

Adjuvant chemotherapy in colorectal cancer: A joint analysis of randomised trials by the Nordic gastrointestinal tumour adjuvant therapy group

Due to uncertainties regarding clinically meaningful gains from adjuvant chemotherapy after colorectal cancer surgery, several Nordic Groups in the early 1990s initiated randomised trials to prove or reject such gains. This report gives the joint analyses after a minimum 5-year follow-up. Between October 1991 and December 1997, 2 224 patients under 76 years of age with colorectal cancer stages II

Budesonide in Crohn's disease: Findings of a compassionate-use program

Background/Aims: Budesonide controlled-release (CR) capsules are effective for inducing remission of Crohn's disease (CD) and are associated with fewer side effects than conventional corticosteroids. A compassionate-use program was implemented in countries where this treatment was unavailable. This paper reports the findings of this program. Methodology: Physicians were allowed to apply to AstraZe

Prosodic signalling of (un)expected information in South Swedish : an interactive manipulation experiment

Starting from the German pitch peak timing categories and their communicative functions, it is asked how these functions would be expressed in South Swedish. The aim is to get a first impression as regards potentially relevant prosodic parameters associated with the expression of expected vs. unexpected information in South Swedish. For that, an interactive manipulation experiment is conducted, wh

The human antibody repertoire to infectious agents: implications for disease pathogenesis

Antibodies are critical entities used for the protection of an individual organism against infection and disease. Through a complex series of events genes rearrange to encode repertoires of molecules, which are tested for their ability to identify foreign molecules. In this report, we discuss factors defined by the individual as well as by infectious organisms that shape the antibody repertoire. A

Judisk tro och kristen i ett religionsteologiskt perspektiv

The article examines some of the tradition answers to the questions what differs Judaism from Christianity, comparing those from antiquity to answers articulated during the 19th and 20th centuries. It is argued that representatives of Christianity constantly need to examine traditional answers. The encounter with living Judaism is essential, with the words of Leo Baeck: "Man muss die Juden kennen,

Preliminary evaluation of two fluorescence imaging methods for the detection and the delineation of basal cell carcinomas of the skin

Abstract Background and ObjectiveFluorescence techniques can provide powerful noninvasive means for medical diagnosis, based on the detection of either endogenous or exogenous fluorophores. The fluorescence of δ-aminolevulinic acid (ALA)-induced protoporphyrin IX (PpIX) has already shown promise for the diagnosis of tumors. The aim of the study was to investigate the localization of skin tumors a

Extended operation with or without intraoperative (IORT) and external (EBRT) radiotherapy for gallbladder carcinoma.

BACKGROUND/AIMS: Gallbladder carcinoma is a rare disease with dismal prognosis. However, lately improved survival has been reported after extended operation including liver resection and lymphadenectomy in addition to cholecystectomy. The aim of this study was to evaluate such a surgical strategy with and without adjuvant intra- and postoperative radiotherapy (IORT/EBRT). METHODOLOGY: 20 patients

MORAXELLA CATARRHALIS OUTER MEMBRANE PROTEINS AND INTERACTIONS WITH THE HUMAN IMMUNE SYSTEM

Popular Abstract in Swedish Moraxella catarrhalis är en bakterie som man länge trodde var en del av vår normala bakterieflora och därmed ofarlig. Under de senaste tjugo åren har M. catarrhalis dock visat sig vara en av orsakerna till öroninflammation hos barn och lägre luftvägsinfektioner hos vuxna med någon annan underliggande sjukdom som t.ex. kronisk obstruktiv lungsjukdom (KOL). De senaste 10 Moraxella catarrhalis is frequently colonizing the human respiratory tract, particularly in children. This gram-negative bacterium has during the last two decades been recognized as a pathogen causing otitis media in children and lower respiratory tract infections in adults with predisposing conditions such as chronic obstructive pulmonary disease (COPD). The virulence determinants of M. catarrhal

För få kranskärlspatienter får lipidsänkande behandling [Few patients with coronary diseases are receiving lipid-lowering therapy]

I Sverige finns sedan flera år riktlinjer för hur förhöjda blodfetter bör behandlas hos patienter med kranskärlssjukdom. Generellt är intresset för och kunskapen om lipidbehandling stort inom den svenska läkarkåren. Trots detta nås uppsatta mål för behandling av blodfetter hos endast en minoritet av patienterna, och hälften av dem får inte någon farmakologisk lipidsänkande behandling, enligt en ny

The impact of six European tree species on the chemistry of mineral topsoil in forest plantations on former agricultural land

Influences on mineral topsoils of common European tree species (oak-Quercus robur L., lime-Tilia cordata Mill., ash-Fraxinus excelsior L., birch-Betula pendula Roth., beech-Fagus sylvatica L. and spruce-Picea abies (L.) Karst.) were studied in 30 to 40-year-old stands planted in adjacent plots on former arable land. Mineral soil samples from two depth layers (0-10 and 20-30 cm) under the different

Evidence for isovector neutron-proton pairing from high-spin states in N=Z Rb-74

High-spin states in the odd-odd N=Z nucleus Rb-74(37)37 were studied using the Ca-40(Ca-40,alphanp) reaction. A previously observed odd-spin T=0 band has been extended to I-pi=(31(+)) and an even-spin T=0 band has been observed for the first time to I-pi=(22(+)); both have a pi(g(9/2))circle timesnu(g(9/2)) structure. A strongly coupled low-spin T=0,K=3 band has been interpreted as being based upo

Single-step affinity purification, partial structure and properties of human platelet cGMP inhibited cAMP phosphodiesterase

The human platelet cilostamide- and cGMP-inhibited cAMP phosphodiesterase (cGI-PDE) was rapidly purified approximately 19,000-fold to apparent homogeneity using single step affinity chromatography on the isothiocyanate derivative of cilostamide coupled to aminoethyl agarose. Within 24 h, 30 micrograms of enzyme protein was obtained from 20 ml of packed platelets. Vmax for cAMP and cGMP was 6.1 and

Laser spectroscopy of gas in scattering media at scales ranging from kilometers to millimeters

Free gases are characterized by their narrow line width, and they can conveniently be studied by laser spectroscopy. The present paper discusses the monitoring of such ambient pressure gases, which are dispersed in scattering media such as aerosol-laden atmospheres, solids, or liquids. Atmospheric work basically constitutes the well-known field of differential absorption lidar (DIAL), while the st