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The Descents of Military Violence against Civilians: a history of the present

Inspired by the works of Michel Foucault and Erling Sandmo, this article explores contemporary discourses of military violence against civilians from a genealogical perspective. The purpose is to shed light on the historicity of certain structures of knowledge, thoughts, politics and ethics that are fundamental for the ways in which military violence against civilians is put into words, interprete

Detection and Identification of a Novel Lactic Acid Bacterial Flora Within the Honey Stomach of the Honeybee Apis mellifera.

This investigation concerned the question of whether honeybees collect bacteria that are beneficial for humans from the flowers that contribute to formation of their honey. Bacteria originating from the types of flowers involved, and found in different anatomic parts of the bees, in larvae, and in honey of different types, were sampled during a 2-year period. 16S rRNA sequencing of isolates and cl

Sustainability Challenges from Climate Change and Air Conditioning Use in Urban Areas

Global climate change increases heat loads in urban areas causing health and productivity risks for millions of people. Inhabitants in tropical and subtropical urban areas are at especial risk due to high population density, already high temperatures, and temperature increases due to climate change. Air conditioning is growing rapidly, especially in South and South-East Asia due to income growth a

Prediction of Alzheimer’s disease in subjects with Mild Cognitive Impairment using biomarkers

Popular Abstract in Swedish Alzheimers sjukdom (eng. Alzheimer’s disease, AD) är den vanligaste orsaken till de- mens. Demens innebär en permanent sänkning av intellektuella förmågor som påverkar individen påtagligt i vardagen. Förekomsten av demenssjukdomar ökar betydligt efter 65 års ålder. AD är en långsamt progredierande sjukdom, som oftast börjar med försämrat närminne. Redan idag är AD en beBackground: Alzheimer’s disease (AD) is the most common cause of dementia. In order to have effect of future disease-modifying therapies for AD, the disease must be identified early, before the patients have developed dementia. Many patients with Mild Cognitive Impairment (MCI) have prodromal AD, but other causes for the syndrome are common. No diagnostic method can identify AD in patients with MC

On the relationship between economic rent and profit

The question of who appropriates the economic rents created by resources and capabilities has remained largely unresolved in strategic management. The aim of this paper is to highlight the problem established strategic management theory faces in explaining value appropriation, and to propose a framework that addresses how R&C affect bargaining power and value appropriation. While resource-base

Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment.

Tasquinimod (a quinoline-3-carboxyamide) is a small molecule immunotherapy with demonstrated effects on the tumor microenvironment (TME) involving immunomodulation, anti-angiogenesis and inhibition of metastasis. A target molecule of tasquinimod is the inflammatory protein S100A9 which has been shown to affect the accumulation and function of suppressive myeloid cell subsets in tumors. Given the m

Consequences of immune system aging in nature: a study of immunosenescence costs in free-living Tree Swallows

Immunosenescence, the aging of the immune system, is well documented in humans and laboratory models and is known to increase infection risk, morbidity, and mortality among the old. Immunosenescence patterns have recently been unveiled in various free-living populations, but their consequences in the wild have not been explored. We investigated the consequences of immunosenescence in free-living T

A Genetic Mouse Model of Parkinson's Disease Shows Involuntary Movements and Increased Postsynaptic Sensitivity to Apomorphine

Alpha-synuclein (SNCA) protein aggregation plays a causal role in Parkinson's disease (PD). The SNCA protein modulates neurotransmission via the SNAP receptor (SNARE) complex assembly and presynaptic vesicle trafficking. The striatal presynaptic dopamine deficit is alleviated by treatment with levodopa (l-DOPA), but postsynaptic plastic changes induced by this treatment lead to a development of in

Size-selectivity of a synthetic high-flux and a high cut-off dialyzing membrane compared to that of the rat glomerular filtration barrier

The aim of the present study was to investigate the size-selectivity of two different synthetic dialyzing membranes, having widely differing sieving properties, with respect to their handling of polydispersed fluorescein isothiocyanate (FITC)-Ficoll, FITC-dextran and of proteins, i.e. I-125-human serum albumin (RISA) and I-125-myoglobin (Myo). Are Ficoll and dextran, compared to proteins, "hyperpe

Long-term molecular remissions in patients with indolent lymphoma treated with rituximab as a single agent or in combination with interferon alpha-2a: A randomized phase II study from the Nordic Lymphoma Group

The purpose of this phase II randomized trial was to evaluate the effect and safety of interferon-2a (IFN) in combination with extended dosing rituximab in patients with symptomatic, advanced indolent lymphoma responding to a standard single course of rituximab. Totally 123 patients were treated with rituximab 375mg/m2 once weekly for 4 weeks leading to 14 complete response (CR; 11%), 56 partial r

Don't Fall Off the Adaptation Cliff: When Asymmetrical Fitness Selects for Suboptimal Traits

The cliff-edge hypothesis introduces the counterintuitive idea that the trait value associated with the maximum of an asymmetrical fitness function is not necessarily the value that is selected for if the trait shows variability in its phenotypic expression. We develop a model of population dynamics to show that, in such a system, the evolutionary stable strategy depends on both the shape of the f

Design and implementation of a distributed Web-based system for itinerary planning in uncertain urban multimodal network

Today’s traffic is one of the main concerns of urban managers. One of the solutions that have been proposed to reduce traffic is encourage people to use public transport instead of personal vehicles, so the quality of public transport should be increased. One way promoting public transport systems quality is creating urban traveler guidance system. In other hand, public transportation network is l

Long-term follow-up after radical cystectomy with emphasis on complications and reoperations: A Swedish population-based survey

Objective. To evaluate outcome after radical cystectomy for primary bladder cancer in a large population-based material. Material and methods. Between 1997 and 2002 all patients treated with radical cystectomy within 3 months after diagnosis of primary bladder cancer without distant metastasis were retrieved through the Swedish Bladder Cancer Registry. A follow-up questionnaire was distributed to