Sökresultat

Filtyp

Din sökning på "*" gav 530988 sökträffar

Solar forcing of climate during the last millennium recorded in lake sediments from northern Sweden

We report on a sediment record from a small lake within the subarctic wetland complex Stordalen in northernmost Sweden covering the last 1000 years. Variations in the content of minerogenic material are found to follow reconstructed variations in the activity of the Sun between the 13th and 18th centuries. Periods of low solar activity are associated with minima in minerogenic material and vice ve

Health impacts of anthropogenic biomass burning in the developed world.

Climate change policies have stimulated a shift towards renewable energy sources such as biomass. The economic crisis of 2008 has also increased the practice of household biomass burning as it is often cheaper than using oil, gas or electricity for heating. As a result, household biomass combustion is becoming an important source of air pollutants in the European Union.This position paper discusse

Efficient Purification of CD4+ Lymphocytes from Peripheral Blood Progenitor Cell Products Using Affinity Bead Acoustophoresis

Processing of peripheral blood progenitor cells (PBPC) for clinical transplantation or research applications aims to effectively isolate or deplete specific cell populations, utilizing primarily magnetic or fluorescence activated sorting methods. Here, we investigated the performance of microfluidic acoustophoresis for the separation of lymphocyte subsets from PBPC, and present a novel method for

Health-related quality of life is impaired in active collagenous colitis

Objectives: The characteristic clinical symptoms of collagenous colitis are non-bloody diarrhoea, urgency and abdominal pain. Treatment is aimed at reducing the symptom burden and the disease impact on patients' health-related quality of life. The objective of this study was to analyse health-related quality of life in patients with collagenous colitis. Methods: In a cross-sectional, postal HRQL s

Concentrations of IGF-I and IGFBP-3 and pancreatic cancer risk in the European Prospective Investigation into Cancer and Nutrition

BACKGROUND: Insulin-like growth factors (IGFs) and their binding proteins (BPs) regulate cell differentiation, proliferation and apoptosis, and may have a role in the aetiology of various cancers. Information on their role in pancreatic cancer is limited and was examined here in a case-control study nested within the European Prospective Investigation into Cancer and Nutrition. METHODS: Serum conc

Superantigen activates the gp130 receptor on adipocytes resulting in altered adipocyte metabolism.

The bacteria Staphylococcus aureus is part of the normal bacterial flora and produces a repertoire of enterotoxins which can cause food poisoning and toxic shock and might contribute to the pathogenesis of inflammatory diseases. These enterotoxins directly cross-link the T cell receptor with MHC class II, activating large amounts of T cells and are therefore called superantigens. It was recently d

Effect of deglycosylation on the mediated electrocatalytic activity of recombinantly expressed Agaricus meleagris pyranose dehydrogenase wired by osmium redox polymer

The effect of deglycosylation of pyranose dehydrogenase (PDH) obtained from Agaricus meleagris (Am) and recombinantly expressed in Pichia pastoris on its electrocatalytic activity was investigated. Glycosylated (gAmPDH) and deglycosylated PDH (dgAmPDH) were immobilised on spectrographic graphite (G) simultaneously with an osmium redox polymer (Os-RP) using poly(ethylene glycol)(400) diglycidyl eth

A Context Management Framework for Context-Aware Applications in Mobile Spaces

Purpose – The rapid proliferation of mobile context aware applications has resulted in an increased research interest towards developing specialized context data management strategies for mobile entities. The purpose of this paper is to aim to develop a new way to model mobile entities and manage their contexts accordingly. Design/methodology/approach – This paper proposes the concept of “Mobile

Camouflaged or tanned: plasticity in freshwater snail pigmentation.

By having phenotypically plastic traits, many organisms optimize their fitness in response to fluctuating threats. Freshwater snails with translucent shells, e.g. snails from the Radix genus, differ considerably in their mantle pigmentation patterns, with snails from the same water body ranging from being completely dark pigmented to having only a few dark patterns. These pigmentation differences

Permanent activation of HMGA2 in lipomas mimics its temporal physiological activation linked to the gain of adipose tissue

Objective: In this study the activation of HMGA2 and overexpression by FGF1-driven stimulation of adipose tissue derived stem cells (ADSCs) in adipose tissue tumors were analyzed. In addition, the expression of HMGA2 and PPAR-gamma mRNA were quantified in canine subcutaneous abdominal adipose tissue from normal and overweight purebred dogs. Design and Methods: ADSCs and adipose tissue explants sti

Evaluation of Planck mean coefficients for particle radiative properties in combustion environments

Thermal radiation is the dominating form of heat transfer in several combustion technologies that combust solid fuels, such as pulverized coal combustion and fixed bed combustion. The thermal radiation originates from the hot combustion gases and particles. For accurate modelling of thermal radiation in these environments the selection of the radiative transport model and radiative property model

Hedgehog spin texture and Berry's phase tuning in a magnetic topological insulator

Understanding and control of spin degrees of freedom on the surfaces of topological materials are key to future applications as well as for realizing novel physics such as the axion electrodynamics associated with time-reversal (TR) symmetry breaking on the surface. We experimentally demonstrate magnetically induced spin reorientation phenomena simultaneous with a Dirac-metal to gapped-insulator t

Outcome of Ischemic Foot Ulcer in Diabetic Patients Who Had no Invasive Vascular Intervention.

OBJECTIVE/BACKGROUND: There is limited information regarding outcome in patients not available for revascularisation. Our aim was to identify factors related to ulcer healing in diabetic patients with severe peripheral arterial disease who were not available for revascularisation. METHODS: Diabetic patients with a foot ulcer, consecutively presenting at a multidisciplinary foot centre with systoli

Effects of macroeconomic uncertainty on the stock and bond markets

In this paper we show that the long-run stock and bond volatility and the long-run stock-bond correlation depend on macroeconomic uncertainty. We use the mixed data sampling (MIDAS) econometric approach. The findings are in accordance with the flight-to-quality phenomenon when macroeconomic uncertainty is high. (C) 2015 Elsevier Inc. All rights reserved.

Comparison and Analysis of Heat Transfer in Aluminum Foam Using Local Thermal Equilibrium or Nonequilibrium Model

Aluminum foams are favorable in modern thermal engineering applications because of the high thermal conductivity and the large specific surface area. The present study aims to investigate an application of porous aluminum foam by using the local thermal equilibrium (LTE) and local thermal nonequilibrium (LTNE) heat transfer models. Three-dimensional simulations of laminar flow (porous foam zone),

Association of subclinical inflammation with deterioration of glycaemia before the diagnosis of type 2 diabetes: the KORA S4/F4 study

Aims/hypothesis The role of biomarkers of subclinical inflammation in the early deterioration of glycaemia before type 2 diabetes is largely unknown. We hypothesised that increased levels of circulating proinflammatory biomarkers and decreased circulating adiponectin would be associated with 7 year increases of HbA(1c) in non-diabetic individuals. Methods This study was based on individuals who pa

Hygroscopic properties of the ambient aerosol in southern Sweden - a two year study

The hygroscopic growth of the atmospheric aerosol is a critical parameter for quantifying the anthropogenic radiative forcing. Until now, there has been a lack of long term measurements due to limitations in instrumental techniques. In this work, for the first time the seasonal variation of the hygroscopic properties of a continental background aerosol has been described, based on more than two ye

Infliximab alleviates inflammation and ex vivo airway hyperreactivity in asthmatic E3 rats

Tumor necrosis factor-alpha (TNF-alpha) has been implicated in the pathogenesis of asthma, and neutralization of TNF-alpha is an effective therapy for inflammatory diseases. The present study tested the idea that a TNF-alpha antibody, infliximab, may be useful in the management of asthma. E3 rats were immunized with ovalbumin (OVA)/alum and received infliximab intra-peritoneally. Two weeks later,