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Reduction of quality of life in prostate cancer patients : experience among 6200 men in the Nordic countries

Objective: Although many studies have dealt with adverse effects (AEs) and quality of life (QoL) in prostate cancer (PCa) patients, the quantification of the patients’ perspective on AE-related reduction in QoL has been less studied. This study describes the impact of self-reported local (erectile, bowel, urinary dysfunction) or systemic (mental distress, fatigue, virility loss) AEs on QoL reducti

The experience of nurses working within a voluntary network : A qualitative study of health care for undocumented migrants

Purpose: To illuminate the experience of nurses providing health care to undocumented migrants in a voluntary network. Methods and sample: In a qualitative study, semistructured interviews were conducted with RNs regarding their experience of providing health care to undocumented migrants within a voluntary network. The interview transcripts were analysed using the inductive method of content anal

Pictorial and multimodal metaphors of DISTRUST in subverted BP logos from Greenpeace’s ‘Behind the logo’ competition

Trust is a valuable relational asset for companies. A high level of public trust can bring a number of benefits to business organizations, including increased customer satisfaction, higher investor confidence, and fewer regulatory restrictions (Barney and Hansen, 1994; García-Marzá, 2005; Ingenhoff and Sommer, 2010; Pirson and Malhotra, 2011). But trust is also a fragile commodity; it takes a lo

Killing the cMSSM softly

We investigate the constrained Minimal Supersymmetric Standard Model (cMSSM) in the light of constraining experimental and observational data from precision measurements, astrophysics, direct supersymmetry searches at the LHC and measurements of the properties of the Higgs boson, by means of a global fit using the program Fittino. As in previous studies, we find rather poor agreement of the best f

(1)H and hyperpolarized (3)He MR imaging of mouse with LPS-induced inflammation

PURPOSE: To evaluate the lipopolysaccharide (LPS) model of chronic obstructive pulmonary disease (COPD) in mouse with (1)H and hyperpolarized (HP) (3)He MR imaging.MATERIALS AND METHODS: Axial slices of the lung volume were acquired with HP (3)He and (1)H MRI at 4, 24, and 48 h after LPS exposure. A quantitative ventilation index was calculated from two HP (3)He acquisitions. A bronchoalveolar lav

Interleaved echo-planar imaging for fast multiplanar magnetic resonance temperature imaging of ultrasound thermal ablation therapy

PURPOSE: To develop a multiplanar magnetic resonance temperature imaging (MRTI) technique based on interleaved gradient-echo echo-planar imaging (EPI), verify in phantom, develop software tools to process and display data on a clinical scanner in near real-time, and demonstrate feasibility to monitor ultrasound thermal ablation therapy in vivo.MATERIALS AND METHODS: Temperature estimation used com

Verification of single beam treatment planning using a ferrous dosimeter gel and MRI (FeMRI)

A method for analysing and comparing treatment planning system (TPS) data and ferrous dosimeter gel measurements evaluated with MRI (FeMRI) was developed, including image processing to final absorbed dose images. Measurements were analysed according to this method and FeMRI data were thereby compared with the TPS-calculated dose distribution. For photons, differences between FeMRI- and TPS dose da

Improvements in absorbed dose measurements for external radiation therapy using ferrous dosimeter gel and MR imaging (FeMRI)

A ferrous gel, based on ferrous (Fe) sulphate and agarose, was used with a clinical magnetic resonance imaging (MRI) scanner to obtain relative dose distribution data from therapeutic photon and electron beams. The FeMRI gel was scanned using a new MRI acquisition protocol optimized for T1 measurements. Thorough comparisons with silicon semiconductor detector and ionization chamber measurements, a

Three-dimensional dose mapping from gamma knife treatment using a dosimeter gel and MR-imaging

A new method has been investigated for the mapping of dose distributions in three dimensions delivered by the Leksell gamma knife. The irradiation unit is used to selectively treat small volumes in the brain with single high doses of ionising radiation--a treatment procedure known as radiosurgery. The dosimetry method investigated utilises a dosimeter gel consisting of ferrous sulphate solution an

Local interactions and protein folding : A three-dimensional off-lattice approach

The thermodynamic behavior of a three-dimensional off-lattice model for protein folding is probed. The model has only two types of residues, hydrophobia and hydrophilic. In absence of local interactions, native structure formation does not occur for the temperatures considered. By including sequence independent local interactions, which qualitatively reproduce local properties of functional protei

Human echolocation using click trains and continuous noise

Blind people may detect objects from the information in reflected sounds, echolocation. Detection as a function of the number of clicks compared to a continuous noise was tested by presenting clicks of 5 ms with rates from 1 to 64 clicks during a 500 ms period and a 500-ms continuous white noise. The sounds were recorded in an ordinary room through an artificial binaural head. The reflecting objec

The use of operator factorization for linear control and estimation

The linear filtering, prediction and smoothing problems as well as the linear quadratic control problems can very generally be formulated as operator equations using basic linear algebra.The equations are of Fredholm type II, and they are difficult to solve directly.It is shown how the operator can be factorized into two Volterra operators using a matrix Riccati equation. Recursive solution of the

Steady-state performance of an infinitely fast reaction in a three-dimensional open Stokes flow

We investigate the steady-state performance of a single irreversible mixing-controlled reaction between segregated reactant streams entering the annular gap between coaxial cylinders that can rotate independently. The three-dimensional Stokes flow results from the superposition of a pressure-driven Poiseuille flow along the mixer axis, and a cross-sectional Couette flow generated by the steady rot