Recently, epidemiological evidence has suggested that hypopituitarism with untreated growth hormone deficiency (GHD) is associated with a high incidence of cardiovascular mortality and that women are particularly at risk. In the present study, the incidence of cardiovascular disease and prevalence of cardiovascular risk factors in 33 such women was assessed and compared with matched controls. A si

The first experiment using radioactive beams post-accelerated by the HIE-ISOLDE facility has enabled to obtain a precise set of B(E2) transition probabilities in neutron-rich 74,76Zn isotopes. The resulting B(E2; 2+1→0+1) values are consistent with those determined in earlier REX-ISOLDE measurements. While the B(E2; 4+1→2+1) transition probability in 76Zn is also in agreement with earlier Coulomb-

This is the first volume of a three-volume collection of primary sources examines philosophy and literature in the nineteenth-century Britain. Accompanied by extensive editorial commentary, this collection will be of great interest to students and scholars of British Literature and Philosophy.

This study investigates the interplay between morality, impoliteness, and moral order in the online harassment of Swedish journalists on Twitter. It reveals how impoliteness serves as a tool to harm the media's epistemic credibility, rooted in anti-press and populist rhetoric, and exert destructive informal social control. The highlighted paradox is that provisions for freedom of speech, designed

This study sought to evaluate the historical impact of changes to an ordering page of an online travel agency on its conversion rates. Data gathered from the website over a year, detailing aspects such as travel dates, prices, itineraries, number of passengers, travel time, and carriers, was analyzed. External data sources were also included, with the dataset covering 12 changes to the website'

BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) can be associated with mutations, deletions, or hybrid genes in factor H-related (FHR) proteins.METHODS: A child with aHUS was investigated. Genetics was assessed by Sanger and next generation sequencing. Serum FHR5 was evaluated by immunoblotting, ELISA, and by induction of rabbit red blood cell hemolysis in the presence/absence of recombinant

AbstractSevere perineal trauma (SPT) is a serious complication following vaginal birth. To reduce its incidence rate, various preventive strategies have been implemented in Swedish obstetric units. Collegial midwifery assistance (CMA), involving an additional midwife being present during the active second stage of labour, is a clinical practice that was evaluated in the Oneplus trial, which proved

Objective: To study the impact of GH dose and age at GH start in girls with Turner syndrome (TS), aiming for normal height and age at pubertal onset (PO) and at adult height (AH). However, age at diagnosis will limit treatment possibilities. Methods: National multicenter investigator-initiated studies (TNR 87-052-01 and TNR 88-072) in girls with TS, age 3–16 years at GH start during year 1987–1998

The Rieger syndrome is an autosomal dominant disease characterized by ocular, craniofacial, and umbilical defects. Patients have mutations in PITX2, a paired-bicoid homeobox gene, also involved in left/right polarity determination. In this study we have identified a family of genes for enzymes responsible for hydroxylizing lysines in collagens as one group of likely cognate targets of PITX2 transc

Naturally occurring antisense RNAs in prokaryotes are generally short, highly structured and untranslated. Stem-loops are always present, and loop regions serve as primary recognition structures in most cases. Single-stranded tails or internal unstructured regions are required for initiation of stable pairing between antisense and target RNA. Most antisense RNAs contain bulged-out nucleotides or s

The BARX genes 1 and 2 are Bar class homeobox genes expressed in craniofacial structures during development. In this report, we present the genomic structure, chromosomal localization, and polymorphic markers in BARX2. The gene has four exons, ranging in size from 85 to 1099 bp. BARX2 is localized on human chromosome 11q25, as determined by radiation hybrid mapping. In the mouse, Barx2 is coexpres

Objectives. Postural orthostatic tachycardia syndrome (POTS) is characterized by cardiovascular autonomic dysfunction of unknown etiology with high a prevalence of gastrointestinal symptoms. The aim of the present study was to examine sociodemographic, lifestyle, and nutritional factors as well as inflammatory markers in patients with POTS. Materials and Methods. Forty-three patients with POTS and

Technology is increasingly being integrated into Age-Friendly Environments (AFEs). This study explores how technology is manifested in AFE policies in China. We conducted a content analysis of 176 policies spanning seven years to identify the relationship between technology and AFEs, and the characteristics of policy development. The findings indicate that technology plays a role in advancing a sm

The present dissertation concerns typologically unusual ways of encoding manner information, namely verbal affixes (manner affixes), incorporated constituents (incorporated manner modifiers) and auxiliary verbs (manner adverbial verbs). A key proposal is that all three are overt realizations of syntactic heads merged in the clausal spine, thereby presenting novel data that can be used to probe int

It is well known that the intensive biogeochemical activity in hyporheic zone of groundwater and antibiotic contaminated river water induced the pollution diffusion and variation of biogeochemical transformation. However, the complex interaction process caused by water level fluctuation is difficult to accurately depict on a larger, catchment scale. Therefore, a loosely coupled HYDRUS-3D/GMS was e