Humans have an irresistible inclination to coordinate actions with others, leading to species-unique forms of cooperation. According to the highly influential Shared intentionality theory (SITh), human cooperation is made possible by shared intentionality (SI), typically defined as a suite of socio-cognitive and motivational traits for sharing psychological states with others, thereby enabling ind

Protein-DNA interactions are involved in many biological processes essential for gene expression and regulation. To understand the molecular mechanisms of protein-DNA recognition, it is crucial to analyze and identify DNA-binding residues of protein-DNA complexes. Here, we proposed a novel descriptor shape string and another two related features shape string PSSM and shape string pair composition

This text deals with the analysis of the removal of the monument to Soviet Marshal Ivan Konev from the Prague 6 district, an important part of the capital of the Czech Republic. The given monument was built during the Soviet occupation of Czechoslovakia in 1980 and removed in 2020. The primary reason for the removal was the dissatisfaction of the political representation of Prague 6 and the leader

Background: Tuberculosis (TB) and diabetes mellitus (DM) have negative synergistic impact on each other. Global guidelines recommend collaborative efforts to address this synergy, but implementation has been slow. Part of the reason is lack of adequate evidence on the operational feasibility of existing tools and mechanisms of collaboration. The objective of this study was to assess the yield of D

To end the global tuberculosis (TB) epidemic and eliminate TB, countries around the world committed to significantly expanding the scope of their efforts, including rapid uptake of new tools, interventions, and strategies, and envisioned a world free of TB. Between 2010 and 2020, Ethiopia experienced a 5% average annual decline in TB incidence. However, at that current rate, ending the TB epidemic

OBJECTIVES: Our objective was to evaluate the impact of a service delivery model led by membership-based associations called Iddirs formed by women on tuberculosis preventive treatment (TPT) initiation and completion rates among children.DESIGN: Comparative, before-and-after study design.SETTING: Three intervention and two control districts in Ethiopia.PARTICIPANTS: Children who had a history of c

BACKGROUND: The Xpert MTB/RIF Ultra (Xpert-Ultra) assay provides timely results with good sensitivity and acceptable specificity with stool specimens in children for bacteriological confirmation of tuberculosis (TB). This study aims to optimize the Simple One-Step (SOS) stool processing method for testing stool specimens using the Xpert-Ultra in children and adults in selected health facilities in

INTRODUCTION: Successful treatment of tuberculosis depends to a large extent on good adherence to treatment regimens, which relies on directly observed treatment (DOT). This in turn requires frequent visits to health facilities. High costs to patients, stigma and burden to the health system challenged the DOT approach. Digital adherence technologies (DATs) have emerged as possibly more feasible al

BACKGROUND: Patients with diabetes mellitus (DM) are at increased risk of developing TB, but the best screening algorithm for early detection and treatment of TB remains unknown. Our objective was to determine if combining routine chest X-ray screening could have a better yield compared with symptom-based screening alone.METHODS: We conducted this cross-sectional study between September 2020 and S

Early detection of breast cancer is important to reduce morbidity and mortality. Access to breast imaging is limited in low- and middle-income countries compared to high-income countries. This contributes to advance-stage breast cancer presentation with poor survival. Pocket-sized portable ultrasound device, also known as point-of-care ultrasound (POCUS), aided by decision support using deep learn

How do politicians use moral appeals in their rhetoric? Previous research suggests that morality plays an important role in elite communication and that the endorsement of specific values varies systematically across the ideological spectrum. We argue that this view is incomplete since it only focuses on whether certain values are endorsed and not how they are contextualized by politicians. Using

Power dissipation has been the major challenge in the downscaling of transistor technology. Metal-Oxide-Semiconductor Field-Effect Transistors (MOSFETs) have struggled to keep a low power consumption while still maintaining a high performance due to the low carrier mobilities of Si but also due to their inherent minimum inverse subthreshold slope (S ≥ 60 mV/dec) which is limited by thermionic emis