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A Theory of Value for Value-Based Feature Selection in Software Engineering

Value-Based Software Engineering stresses the role of value in software related decisions. In the context of feature selection, software features judged to provide higher value take priority in the development process. This paper focuses on what value means when selecting software features. Using grounded theory, we conducted and analyzed semi-structured interviews with 21 key stakeholders (decisi

Time for some changes to ICIS? Reflections on our highest-quality conference

In this commentary, we reflect on the program chair experience of ICIS 2015 to pass on some useful organizational memory for the IS community at large. We also reflect on volunteer effort required for a high-quality conference and the challenges of maintaining quality over a diverse and dispersed reviewing effort. We ask whether we can count on this volunteer effort in a changing higher education

Amidst an Urban Archive and Rustling Wind: Of Mediation in Digital and Nonsite Performance Environments.

This presentation departs from two recent collaborative projects. The former An Urban Archive as an English Garden (Franzson, 2019) was instigated by Davíð Brynjar Franzson and revolved around a sonic hologram and performance therein. The second project, Violin with Þytur (Olofsson & Stefánsdóttir, 2021) was a collaboration with Kent Olofsson which resulted in a performance within the nine mon

Cyclosporine as Therapy for Traumatic Brain Injury

Drug development in traumatic brain injury (TBI) has been impeded by the complexity and heterogeneity of the disease pathology, as well as limited understanding of the secondary injury cascade that follows the initial trauma. As a result, patients with TBI have an unmet need for effective pharmacological therapies. One promising drug candidate is cyclosporine, a polypeptide traditionally used to a

Do central bank speeches help predict monetary policy?

This paper studies the information contained in central bank speeches, focusing on predicting future monetary policy. Departing from previous papers which use mainly dictionary-based methods, we employ the deep transfer learning technique to process the text data. We find that central bank speeches can be used to predict policy rate change over the next three months (with an accuracy of 71.4%). In

FDML versus GMM for Dynamic Panel Models with Roots Near Unity

This paper evaluates the first-differenced maximum likelihood (FDML) and the continuously updating system generalized method of moments (CU-GMM) estimators of dynamic panel models when the data is close to non-stationary. This case is far from trivial, as a high degree of persistence is the norm rather than the exception in economic panels, particularly in financial management. While the CU-GMM is

Altered brain metabolism in frontotemporal dementia and psychiatric disorders : involvement of the anterior cingulate cortex

Background: Behavioural symptoms and frontotemporal hypometabolism overlap between behavioural variant of frontotemporal dementia (bvFTD) and primary psychiatric disorders (PPD), hampering diagnostic distinction. Voxel-wise comparisons of brain metabolism might identify specific frontotemporal-(hypo)metabolic regions between bvFTD and PPD. We investigated brain metabolism in bvFTD and PPD and its

An atlas of genetic determinants of forearm fracture

Osteoporotic fracture is among the most common and costly of diseases. While reasonably heritable, its genetic determinants have remained elusive. Forearm fractures are the most common clinically recognized osteoporotic fractures with a relatively high heritability. To establish an atlas of the genetic determinants of forearm fractures, we performed genome-wide association analyses including 100,0

A search for new resonances in multiple final states with a high transverse momentum Z boson in √s = 13 TeV pp collisions with the ATLAS detector

A generic search for resonances is performed with events containing a Z boson with transverse momentum greater than 100 GeV, decaying into e + e − or μ + μ −. The analysed data collected with the ATLAS detector in proton-proton collisions at a centre-of-mass energy of 13 TeV at the Large Hadron Collider correspond to an integrated luminosity of 139 fb −1. Two invariant mass distributions are exami

Riskfylld socialisering i området som policyproblem: Policyn CTC som rumskapande biopolitisk maktteknologi

In this thesis I use a feminist poststructuralist framework to analyse a policy document within the program Communities That Care, implemented in Malmö, Sweden. This urban security initiative makes the socialization of children and youth its object, and problematizes the social and built organisation of local areas as a root cause of urban insecurity. It creates spaces for intervention (CTC-areas)

Caffeine Intake, Plasma Caffeine Level, and Kidney Function : A Mendelian Randomization Study

Caffeine is a psychoactive substance widely consumed worldwide, mainly via sources such as coffee and tea. The effects of caffeine on kidney function remain unclear. We leveraged the genetic variants in the CYP1A2 and AHR genes via the two-sample Mendelian randomization (MR) framework to estimate the association of genetically predicted plasma caffeine and caffeine intake on kidney traits. Genetic

Tumour origin, diagnostic accuracy and histopathological evaluation in patients with periampullary cancer : nationwide cohort study

Background: The prevalence of different periampullary cancers (pancreatic ductal adenocarcinoma, distal cholangiocarcinoma, ampullary cancer and duodenal cancer) is heterogeneous in the literature. During the 2010s, a standardized histopathological protocol for pancreatoduodenectomy specimens based on axial slicing was adopted in Sweden. The present study sought to provide information about periam

A plant-based milk powder that functions as a substitution for regular milk powder

This project tested the potential of plant based milk powders to function as an animal-based milk powder by testing them on multiple characteristics. The powders were produced using spray drying techniques, obtained using formulations differentiating in protein amount, ratio of maltodextrin:sucrose and two different protein sources. The different ratios were 100% sucrose; 100% maltodextrin; 50% ma

[18F]PSMA-1007 PET is comparable to [99mTc]Tc-DMSA SPECT for renal cortical imaging.

BACKGROUND: Scintigraphy using technetium-99m labelled dimercaptosuccinic acid ([99mTc]Tc-DMSA), taken up in the proximal tubules, is the standard in functional imaging of the renal cortex. Recent guidelines recommend performing [99mTc]Tc-DMSA scintigraphy with single photon emission computed tomography (SPECT). Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET)

Longitudinal changes in hippocampal texture from healthy aging to Alzheimer's disease

Early detection of Alzheimer's disease is essential to develop preventive treatment strategies. Detectible change in brain volume emerges relatively late in the pathogenic progression of disease, but microstructural changes caused by early neuropathology may cause subtle changes in the MR signal, quantifiable using texture analysis. Texture analysis quantifies spatial patterns in an image, such as

Exploring the relationship between social jetlag with gut microbial composition, diet and cardiometabolic health, in the ZOE PREDICT 1 cohort

Purpose: In this study, we explore the relationship between social jetlag (SJL), a parameter of circadian misalignment, and gut microbial composition, diet and cardiometabolic health in the ZOE PREDICT 1 cohort (NCT03479866). Methods: We assessed demographic, diet, cardiometabolic, stool metagenomics and postprandial metabolic measures (n = 1002). We used self-reported habitual sleep (n = 934) to