Caffeine is a psychoactive substance widely consumed worldwide, mainly via sources such as coffee and tea. The effects of caffeine on kidney function remain unclear. We leveraged the genetic variants in the CYP1A2 and AHR genes via the two-sample Mendelian randomization (MR) framework to estimate the association of genetically predicted plasma caffeine and caffeine intake on kidney traits. Genetic

Background: The prevalence of different periampullary cancers (pancreatic ductal adenocarcinoma, distal cholangiocarcinoma, ampullary cancer and duodenal cancer) is heterogeneous in the literature. During the 2010s, a standardized histopathological protocol for pancreatoduodenectomy specimens based on axial slicing was adopted in Sweden. The present study sought to provide information about periam

This project tested the potential of plant based milk powders to function as an animal-based milk powder by testing them on multiple characteristics. The powders were produced using spray drying techniques, obtained using formulations differentiating in protein amount, ratio of maltodextrin:sucrose and two different protein sources. The different ratios were 100% sucrose; 100% maltodextrin; 50% ma

BACKGROUND: Scintigraphy using technetium-99m labelled dimercaptosuccinic acid ([99mTc]Tc-DMSA), taken up in the proximal tubules, is the standard in functional imaging of the renal cortex. Recent guidelines recommend performing [99mTc]Tc-DMSA scintigraphy with single photon emission computed tomography (SPECT). Prostate-specific membrane antigen (PSMA) targeted positron emission tomography (PET)

Early detection of Alzheimer's disease is essential to develop preventive treatment strategies. Detectible change in brain volume emerges relatively late in the pathogenic progression of disease, but microstructural changes caused by early neuropathology may cause subtle changes in the MR signal, quantifiable using texture analysis. Texture analysis quantifies spatial patterns in an image, such as

Purpose: In this study, we explore the relationship between social jetlag (SJL), a parameter of circadian misalignment, and gut microbial composition, diet and cardiometabolic health in the ZOE PREDICT 1 cohort (NCT03479866). Methods: We assessed demographic, diet, cardiometabolic, stool metagenomics and postprandial metabolic measures (n = 1002). We used self-reported habitual sleep (n = 934) to

The use of protective gloves is of importance in workplaces where hazardous chemicals are handled, including the chemical industry, the plastic industry, as well as in environments such as dental practices, hairdressing, and beauty salons. Occupational dermatology can provide crucial advice regarding how to avoid or protect the patient against allergens found in the work environment and provide th

Systemic risk management is always of vital importance for financial stability, meanwhile Environmental (E), Social (S) and Governance (G) are a popular framework on a global scale which is used to assess business risks and opportunities. However, there is relatively little research about the relationship between ESG and systemic risk, especially in developing markets. Therefore, this study aims t

This Letter reports on the first measurements of transverse momentum dependent flow angle ψn and flow magnitude vn fluctuations determined using new four-particle correlators. The measurements are performed for various centralities in Pb-Pb collisions at a center-of-mass energy per nucleon pair of sNN = 5.02 TeV with ALICE at the CERN Large Hadron Collider. Both flow angle and flow magnitude fluct

Molecular junctions offer significant potential for enhancing thermoelectric power generation. Quantum interference effects and associated sharp features in electron transmission are expected to enable the tuning and enhancement of thermoelectric properties in molecular junctions. To systematically explore the effect of quantum interferences, we designed and synthesized two new classes of porphyri

This article investigates the emergence and early use of possessive HAVEgot in English. Two hypotheses about its emergence are tested on historical data (c.1460–1760). One hypothesis is based on communicative functionality, suggesting that got was inserted as a ‘pattern preserver’ to compensate for the increased reduction of HAVE. The other hypothesis invokes the conventionalization of an invited This article investigates the emergence and early use of possessive havegot in English. Two hypotheses about its emergence are tested on historical data (c.1460–1760). One hypothesis is based on communicative functionality, suggesting that got was inserted as a ‘pattern preserver’ to compensate for the increased reduction of have. The other hypothesis invokes the conventionalization of an invited

The XUV beams generated via high order harmonic generation (HHG) in gases have spatial properties evolving with the harmonic order. It leads to chromatic aberrations when the harmonics are focussed so that, locally, the spectral content can change significantly during propagation [1-3] especially near focus.

Nancy Frasers arbete är ett exempel på kritik som en rad teoretiker har riktat mot Marshall, och inte minst mot hans förgivettagande att nationen är den givna ram inom vilken medborgarskap, det vill säga rättigheter av olika slag, anordnas och tillhandahålls. Även om vi i dag lever i en tid av globalisering och världsomspännande migration där rörlighet är mer regel än undantag, så är nationalismen

Desk lamps were originally designed for reading and craftsmanship. However, with the increasing prevalence of com- puter-based work and the rise of remote and hybrid work arrangements due to the COVID-19 pandemic, our needs for lighting have evolved. This project aimed to create a versatile desk lamp suitable for both traditional tasks like reading and writing, as well as modern computer

Vad krävs för att lyckas och trivas som forskare? Den här bloggen ger verktyg för att navigera en akademisk karriär utan att försaka fritid och familj.