Background: As the placental vessels are dependent on the normal balance of procoagulant and anticoagulant mechanisms, inherited thrombophilia may be associated with fetal loss. Objectives: We performed a prospective study to investigate the relation between inherited thrombophilia and fetal loss, and the influence of thromboprophylaxis on pregnancy outcome. Patients and methods: Women were enroll

The legacy of Nisbett and Wilson's classic article, Telling More Than We Can Know: Verbal Reports on Mental Processes (1977), is mixed. It is perhaps the most cited article in the recent history of consciousness studies, yet no empirical research program currently exists that continues the work presented in the article. To remedy this, we have introduced an experimental paradigm we call choice bli

A missense mutation, FV-IIe359Thr (FV Liverpool), associated with thrombosis has recently been described. This mutation creates an additional potential N-linked glycosylation site (Asn-X-Ser/Thr) in factor V (FV) at Asn357 that could interfere with secretion and/or protein interactions. To investigate the molecular pathology of FV-IIe359Thr, the mutation was created by site-directed mutagenesis an

Cystihalysites sp. from the Ludfordian Eke Formation on Gotland, Sweden, is the youngest halysitid coral found in Baltoscandia. Halysitids had earlier been considered as absent at this level and were thought to have disappeared in the Gorstian-lower Ludfordian Hemse Group. The new material indicates that at least one species survived the early parts of the Lau extinction event.

A parametric study is reported where a femtosecond prepulse is used to change the target properties before the interaction with a multi-terawatt laser pulse which accelerates protons from a foil target. The proton spectrum as function of the prepulse delay and intensity, up to 1.5 ns and up to 3x106 W/cm2, respectively, shows a global decrease of the maximum proton energy with delay and intensity.

Protein C inhibitor (PCI) is a member of the serpin family that has many biological functions. In blood it acts as a procoagulant, and, in the seminal vesicles, it is required for spermatogenesis. The activity of PCI is affected by heparin binding in a manner unique among the heparin binding serpins, and, in addition, PCI binds hydrophobic hormones with apparent specificity for retinoids. Here we

Twenty-one males underwent an interview, clinical investigation, and measurement of urine flow and residual volume 15-25 years after surgery. Although surgical techniques have been improved during recent decades, the results of hypospadias repair made 20 years ago are nethertheless acceptable and most patients regard the outcome as satisfactory.

Cut-off levels for serum retinol levels of 20 micrograms/dl for marginal and 10 micrograms/dl for definite deficiency have been advocated and extensively used in population studies. However, the blood serum levels of retinol of the newborn are known to be very low and although the age dependency of the retinol binding protein has been described, the normal levels of serum retinol at different ages

Chemotherapy resistance remains a major obstacle to successful treatment of ovarian cancer patients. Therefore, increased knowledge of underlying mechanisms and identification of predictive factors are of great importance. Standard treatment for ovarian carcinoma is surgery followed by platinum-based chemotherapy. In this study, we aimed to search for genes or genomic regions involved in platinum

Photodynamic therapy for the treatment of cancer relies on the presence of light, sensitizer and oxygen. By monitoring these three parameters during the treatment a better understanding and treatment control could possibly be achieved. Here we present data from in vivo treatments of solid skin tumors using an instrument for interstitial photodynamic therapy with integrated dosimetric monitoring. B

Purpose: Rollators are used in order to make mobility possible for people with restricted walking ability. The use of rollators is increasing, but little is known about outcomes. The aim of this study was to investigate users' satisfaction with rollators. Method: A follow-up study was carried out in seven Danish municipalities. One month after they got their device, 89 users of rollators were inte

To evaluate the relative importance of climatic factors and the level of natural canopy disturbance on sapling growth rates, terminal shoot increment of Norway spruce (Picea abies (L.) Karst.) saplings was analyzed in old-growth Sphagnum-Myrtillus forests of the European southern boreal zone (Tver Region, Russia). For a 5-year period, terminal increments were retrospectively measured in 225 saplin

We show that the travelling salesman problem in bounded-degree graphs can be solved in tune O((2 - epsilon)(n)), where epsilon > 0 depends only on the degree bound but not on the number of cities, n. The algorithm is a variant of the classical dynamic programming solution due to Bellman, and, independently; Held and Karp. In the case of bounded integer weights on the edges, we also present a polyn

This study uses aggregate data for 23 Organization for Economic Cooperation and Development (OECD) countries over the 1960-1997 period to examine the relationship between macroeconomic conditions and deaths. The main finding is that total mortality and deaths from several common causes rise when labor markets strengthen. For instance, controlling for year effects, location fixed-effects (FE), coun

This study aimed to characterize the ST-recovery loop and assess which range of heart rates (HRs) best discriminates between patients with and without significant coronary artery stenosis. Bicycle exercise tests were undertaken in 44 men and IS women with coronary artery disease (CAD) and in 59 controls (26 men, 33 women) in the same age range with no signs of CAD. The ST level and the ST-segment

We report a theoretical study of the electronic structure and optical properties of free-standing semiconductor nanowires, based on an atomistic tight-binding approach. It is shown that the optical transition between the valence-band maximum and conduction-band minimum of an intrinsic nanowire is fully polarized along the wire axis, and this giant polarization anisotropy can be explained in terms

PURPOSE: In an experimental study in rats a correlation between nutritional status and hepatic attenuation in CT and signal intensities in MR imaging was shown. Is physiological nutritional status of importance in clinical CT and MR imaging? MATERIAL AND METHODS: In a cross-over study including 12 healthy volunteers (6 women and 6 men, mean age 34 years), CT and MR imaging of the liver were perfor