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The level of glucose-6-phosphate dehydrogenase activity strongly influences xylose fermentation and inhibitor sensitivity in recombinant Saccharomyces cerevisiae strains.

Disruption of the ZWF1 gene encoding glucose-6-phosphate dehydrogenase (G6PDH) has been shown to reduce the xylitol yield and the xylose consumption in the xylose-utilizing recombinant Saccharomyces cerevisiae strain TMB3255. In the present investigation we have studied the influence of different production levels of G6PDH on xylose fermentation. We used a synthetic promoter library and the copper

Tunneling through nanosystems: Combining broadening with many-particle states

We suggest an approach for transport through finite systems based on the Liouville equation. By working in a basis of many-particle states for the finite system, Coulomb interactions are taken fully into account and correlated transitions by up to two different contact states are included. This latter extends standard rate equation models by including level-broadening effects. The main result of t

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Abstract in Spanish Inger Enkvist, catedrática de español de la Universidad de Lund, Suecia, trabajó durante tres años en un proyecto de investigación junto con Ángel Sahuquillo, de la Universidad de Sodertorn, también en Suecia, en un proyecto titulado "Identidad e ideología en la literatura hispánica: un estudio basado en la obra de Juan Goytisolo". El presente artículo demuestra que el resultad

Amoxicillin treatment of experimental acute otitis media caused by Haemophilus influenzae with non-beta-lactamase-mediated resistance to beta-lactams: aspects of virulence and treatment

Through alterations primarily in the penicillin-binding proteins, a non-beta-lactamase-mediated resistance to beta-lactams has evolved in Haemophilus influenzae. The virulence of these chromosomally changed strains has been questioned. To ascertain whether these alterations involve a reduction in virulence of H. influenzae and whether they could be advantageous for the bacterium during amoxicillin

Educating the compassionate water engineer - a remedy to avoid future water management failures?

The number of local and regional-scale water management failures appears steadily to increase despite an apparently higher level of engineering solutions at hand. The objective of this paper is to examine the challenges the existing education system needs to meet in order to produce water engineers capable of responding to the complexity of contemporary and future water problems in relation to soc

Analysis of Adaptive Interference Cancellation Using Common-Mode Information in Wireline Communications

Joint processing of common-mode (CM) and differential-mode (DM) signals in wireline transmission can yield significant improvements in terms of throughput compared to using only the DM signal. Recent work proposed the employment of an adaptive CM-reference-based interference canceller and reported performance improvements based on simulation results. This paper presents a thorough investigation of

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Abstract is not available. Author's Reply to correspondence about article "Glomerular endotheliosis in normal pregnancy and pre-eclampsia"

Effects of palatable diets on appetite regulation, appetite peptides and neurogenesis.

Popular Abstract in Swedish Fetma ökar epidemilikt i hela världen, delvis på grund av en ökad konsumption av dieter som innehåller mycket fett och/eller socker. Ghrelin och leptin är hormoner som produceras perifert med effekter på födointag och energihomeostas. Ghrelin i cirkulationen ökar vid energibrist, t ex vid fasta och signalerar därmed hunger. Leptin ökar vid födointag och signalerar mättnObesity is increasing throughout the world at an epidemic rate, partly due to increased consumption of diets rich in fat and/or sugar. Ghrelin and leptin are hormones, originating from the periphery, involved in the regulation of food intake and of maintaining energy homeostasis. Circulating ghrelin levels increase in times of energy deficiency, such as fasting, signalling hunger whereas circulati

Impacts and responsibilities for sustainable tourism: a tour operator's perspective

Tourism is currently responsible for the largest, annual human migration in history. This great movement of people has significant positive and negative consequences on nature, societies, cultures and economies. Desired worldwide for its economic benefits, tourism is anticipated to double during the next 20 years, and the multiple consequences of such rapid growth,,call for a preventative approach

Automated flow enzyme-linked immunosorbent assay (ELISA) system for analysis of methyl parathion

sensitive detection of pesticides is of utmost importance in environment pesticides in agricultural and environmental samples wherein antibodies are employed against the target molecules. Accurate diagnosis depends on the affinity and specificity of the antibody preparation used, and high affinity antibodies are essential for the detection of very small amounts of pesticides. Enzyme linked immuno

A Market-driven Requirements Engineering Process - Results from an Industrial Improvement Programme

In market-driven software evolution, the objectives of a requirements engineering process include the envisioning and fostering of new requirements on existing packaged software products in a way that ensures competitiveness in the market place. This paper describes an industrial, market-driven requirements engineering process which incorporates continuous requirements elicitation and prioritisati