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Background: The functional impact of breathlessness is assessed using the modified Medical Research Council (mMRC) scale for chronic respiratory disease and with the New York Heart Association Functional Classification (NYHA) scale for heart failure. We evaluated agreement between the scales and their concurrent validity with other clinically relevant patient-reported outcomes in cardiorespiratory

Uppåkra har länge framstått som en solitär i ett tomt landskap. Bakgrunden till denna uppfattning, snarare än realitet, kommer av det faktum att få arkeologiska undersökningar har gjorts i centralplatsens närhet. Inom en fem kilometers radie runt Uppåkra har emellertid flera undersökningar utförts under 2000-talet inom uppdragsarkeologin. Dessa har skapat en hälsosam kontrast till den fyndrika pla

Variations in the phosphorylation and glycosylation patterns of the common κ-casein (CN) variants A and B have been explored, whereas studies on variant E heterogeneity are scarce. This study reports for the first time the detailed phosphorylation and glycosylation pattern of the κ-CN variant E in comparison with variants A and B. Individual cow milk samples representing κ-CN genotype EE (n = 12)

Stephen Graham and Simon Marvin’s Splintering Urbanism: Networked Infrastructures, Tech- nological Mobilities and the Urban Condition (2001) brought the study of infrastructure to the core of urban studies and inspired the “infrastructural turn” in the social sciences more widely. The book catalyzed a rich trove of research on how technology and society are impli- cated in the production of contem

We investigate the effects of offshoring on job security using matched employer-employee data from Sweden. Between 1997 and 2011, the share of offshoring firms fell from around 25 to 22% while offshoring per worker within offshoring firms almost doubled. We use this variation to contribute to the literature by examining the effects of the neighboring firms’ offshoring (external offshoring) on job

Alzheimer’s Disease (AD) is a devastating neurodegenerative disease associated with massive neuronal cell death during its pathology. The involvement of the amyloid β 42 (Aβ42) peptideand its role in neurotoxicity is now well established. It is known that the production of oligomers during the aggregation of Aβ42 into highly ordered fibrils is responsible for neuronal cell death. However, the effo

Objective: Fenestrated endovascular aortic aneurysm repair (FEVAR) for juxtarenal aortic aneurysm (jAAA) disease is safe and effective with good short- and mid-term outcomes. The durability issues have mainly focused on the proximal and distal seal and target vessel (TV) instability, and long-term data are scarce. In previous studies, we have reported the short-term outcomes after FEVAR and compar

Purpose: Early-onset Alzheimer’s disease (EOAD) and late-onset Alzheimer’s disease (LOAD) differ in neuropathological burden and type of cognitive deficits. Assessing tau pathology and relative cerebral blood flow (rCBF) measured with [18F]flortaucipir PET in relation to cognition may help explain these differences between EOAD and LOAD. Methods: Seventy-nine amyloid-positive individuals with a cl

rapidly and on a large scale, judging from the very short introduction phase for late Slavic pottery and the absence of hybrid forms between this tradition and the local Scandinavian ware. Late Slavic ware became a Scanian cultural trait after only one generation; this tradition is today called “Baltic ware”, as it was produced outside the Slavic area by an increasing number of local potters. AfteThe existence of slavery in Viking-Age and high medieval Scandinavia is accepted as a fact. Law codes, literary sources and some few burials vouch for that. It is, however, more complicated to ascertain regional differences in the use of slaves, their ethnic identities and geographical distribution, as well as changes in the intensity of their exploitation over time. A new source, household potter

Nature-based Solutions (NbS) are currently promoted as a panacea for improving human-nature relations. Yet the way of amplifying and mainstreaming NbS beyond scientific demonstrator projects into policy contexts is still bearing shortcomings, in particular in the uncertain futures of a post-COVID-19 world. Successful NbS amplification may be achieved by (1) using multi-scalar action to balance dif

Why, in the midst of the global Coronavirus pandemic, do so many people seem resistant to the recommendations of established medical experts? In this chapter, I explore possible structural causes of this resistance in the U.S. context. I argue that in the “post-truth” era, attempts to encourage people to wear face masks and get vaccinated confront challenges pertaining to how scientific knowledge

This dissertation analyzes and evaluates several major productions by Danish philosopher and theologian Søren Kierkegaard (1813–1855). It focuses on three works Kierkegaard authored under pseudonyms – Either / Or (1843), Fear and Trembling (1843), and Philosophical Fragments (1844) – and the non-pseudonymously authored Works of Love (1847). The dissertation argues that for Kierkegaard, Christian f

In this study, we demonstrate an acoustofluidic device that enables single-file focusing of submicron particles and bacteria using a two-dimensional (2D) acoustic standing wave. The device consists of a 100 μm × 100 μm square channel that supports 2D particle focusing in the channel center at an actuation frequency of 7.39 MHz. This higher actuation frequency compared with conventional bulk acoust

The clinical utility of microfluidic techniques is often hampered by an unsatisfying sample throughput. Here, the effect of inertial forces on acoustofluidic particle sorting at high sample throughputs is investigated experimentally and theoretically. Polystyrene particles are acoustically prefocused to obtain precise trajectories. At increased flow rates it is observed that the particle stream is

While the association between economic freedom and long-term economic growth has been well documented, the parallel research literature on the distributional consequences of economic freedom is full of conflicting findings. In this paper, we take a step toward reconciling these two bodies of literature by exploring the within-quintile growth consequences of changes in three separate elements of ec

In this 20-year anniversary editorial of ephemera, we discuss independent publishing by situating it in a changing academic landscape – one scarred by despair but also leavened by hope. Twenty years ago, the goal of publishing an open access peer-reviewed journal was a radical political gesture in itself. Today, the model of open access publishing has been appropriated, hollowed out, and commodifi