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Oxford meniscal bearing knee versus the Marmor knee in unicompartmental arthroplasty for arthrosis. A Swedish multicenter survival study

In the Swedish Knee Arthroplasty Study, all 699 Oxford meniscal bearing cemented unicompartmental prostheses (Biomet, Bridgend, UK) were identified and analyzed regarding failure pattern and compared with all Marmor prostheses (Smith & Nephew Richards, Orthez, France) and with a time-, age-, and sex-matched subset of Marmor prostheses using survival statistics expressed as cumulative revision

Mother's Genome or Maternally-Inherited Genes Acting in the Fetus Influence Gestational Age in Familial Preterm Birth

Objective: While multiple lines of evidence suggest the importance of genetic contributors to risk of preterm birth, the nature of the genetic component has not been identified. We perform segregation analyses to identify the best fitting genetic model for gestational age, a quantitative proxy for preterm birth. Methods: Because either mother or infant can be considered the proband from a preterm

Thermo gravimetric study of calcination of dolomite at pressurised conditions

Calcination and carbonation behaviour of dolomite has been studied in a pressurised thermo balance at pressures in the range of 1.1 to 2.3 MPa and for temperatures ranging from 730 to 840 degrees C. The atmosphere consisted of nitrogen containing up to 20 vol.-% carbon dioxide. The calcination of dolomite has been studied as a function of temperature, particle size, and P-CO2. An investigation con

Polarization spectroscopy applied to the detection of trace constituents in sooting combustion

The potential of polarization spectroscopy for the detection of trace constituents in sooting combustion was investigated. It was demonstrated that the directionality of the polarization spectroscopy signal can be exploited to efficiently suppress incoherent interferences, e.g., Rayleigh scattering at soot particles. We also show how polarization spectroscopy compares with laser-induced fluorescen

Significance of hyphal diameter in calculation of fungal bio-volume

Three ways to calculate average hyphal cross section in agarfilm slides were compared in a field study including 5 soil horizons sampled 4 times. The method of calculation strongly affected the estimated value for soil fungal biovolume. Biovolume estimated with the different methods varied by more than 30%. Great differences in average cross section were found between the soil horizons, stressing

Copper-dependent autocleavage of glypican-1heparan sulfate by nitric oxide derived fromintrinsic nitrosothiols.

Cell-surface heparan sulfate proteoglycans facilitate uptake of growth-promoting polyamines [ [Belting, M., Borsig, L., Fuster, M.M., Brown, J.R., Persson, L., Fransson,L.-. and Esko, J.D. (2002) Proc. Natl. Acad. Sci. U.S.A., 99, 371-376] ]. Increased polyamine uptake correlates with an increased number of positively charged N-unsubstituted glucosamine units in the otherwise polyanionic heparan s

Genetic differentiation and hybridization between greater and lesser spotted eagles (Accipitriformes : Aquila clanga, A-pomarina)

Greater and lesser spotted eagles (Aquila clanga, A. pomarina) are two closely related forest eagles overlapping in breeding range in east-central Europe. In recent years a number of mixed pairs have been observed, some of which fledged hybrid young. Here we use mitochondrial (control region) DNA sequences and AFLP markers to estimate genetic differentiation and possible gene flow between these sp

Oligomerization of amyloid A beta(16-22) peptides using hydrogen bonds and hydrophobicity forces

The 16 - 22 amino-acid fragment of the beta-amyloid peptide associated with the Alzheimer's disease, Abeta, is capable of forming amyloid fibrils. Here we study the aggregation mechanism of Abeta(16-22) peptides by unbiased thermodynamic simulations at the atomic level for systems of one, three, and six Abeta(16-22) peptides. We find that the isolated Abeta(16-22) peptide is mainly a random coil i

A 59-kd renal antigen as a new target for rapidly progressive glomerulonephritis

Anti-glomerular basement membrane (anti-GBM) antibodies are the hallmark of anti-GBM disease, which is characterized by rapidly progressive glomerulonephritis. We describe the case of a 58-year-old woman who presented with rapidly progressive glomerulonephritis with typical anti-GBM staining found by means of direct immunofluorescence microscopy, associated with linear immunoglobin G deposits on t

The lycaenid butterfly Polyommatus icarus uses a duplicated blue opsin to see green

The functional significance of gene duplication is rarely addressed at the level of animal behavior. Butterflies are excellent models in this regard because they can be trained and the use of their opsin-based visual pigments in color vision can be assessed. In the present study, we demonstrate that the lycaenid Polyommatus icarus uses its duplicate blue (B2) opsin, BRh2, in conjunction with its l

The von Hippel-Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

Deletions of the short arm of chromosome 3 are often observed in a specific subset of aggressive neuroblastomas (NBs) with loss of distal 11q and without MYCN amplification. The critical deleted region encompasses the locus of the von Hippel-Lindau gene (VHL, 3p25). Constitutional loss of function mutations in the VHL gene are responsible for the VHL syndrome, a dominantly inherited familial cance

Extraction of rosavin from Rhodiola rosea root using supercritical carbon dioxide with water

In this study, a new extraction method for the isolation of rosavin from dried crushed roots of Rhodiola rosea is being developed using supercritical CO2 and water. Rosavin extracts quantitatively and qualitatively were compared to commonly used solvents such as methanol, ethanol and ethyl acetate. By HPLC analysis rosavin was found to be the dominant compound in extracts obtained by both extracti

A simple algorithm for fast correlation attacks on stream ciphers

A new simple algorithm for fast correlation attacks on stream ciphers is presented. The advantages of the new approach are at least two. Firstly, the new algorithm significantly reduces the memory requirements compared with some recent proposals [2],[3]. This allows more powerful attacks than previously. Secondly, the simplicity of the algorithm allows us to derive theoretical results. We determin

Bacterial growth inhibited by a synthetic inhibitor based upon the structure of a human proteinase inhibitor

Cysteine proteinases are important not only in the intracellular catabolism of peptides and proteins1 and in the processing of prohormones and proenzymes2,3, but also in the penetration of normal human tissue by malignant cells4 and possibly microorganisms5, including viruses. Cystatin C is a human cysteine proteinase inhibitor present in extracellular fluids6. We have synthesized peptide derivati