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Background: Acute allergic reactions (AARs) occur shortly after exposure to an allergen, and the severity is on a continuum. Systemic corticosteroids (CS) are mainstay treatment of moderate to severe AARs, whereas those at risk of the most severe AARs (ie, anaphylaxis) are also recommended prescription of epinephrine autoinjectors. There is limited research on the impact of AARs not fulfilling the
Background: ECG abnormalities have been linked to adverse changes in right ventricular (RV) morphology and poor clinical outcomes in repaired Tetralogy of Fallot (rTOF). Our aim was to describe how ECG changes progress in early and intermediate follow-up and whether types of surgical strategy at the time of primary repair affected these changes. Methods: We studied patients with rTOF born 2000–201
To investigate the relationship between gonadotroph function and ultrastructure, we have compared, in parallel in female mice, the effects of several different mutations that perturb the hypothalamic-pituitary-gonadal axis. Specifically, serum and pituitary gonadotrophin concentrations, gonadotrophin gene expression, gonadotroph structure and number were measured. Follicle-stimulating hormone β kn
Currently, both the US and the EU are pursuing industrial policies to support climate mitigation objectives. The climate transition will require increased use of material resources, but the envisioned industrial policies do not sufficiently address resource use, despite the current unsustainable global resource-use trajectory. The lack of industrial policy in this field is therefore relevant and t
Introduction: A well-functioning anti-doping system relies on being perceived by athletes as effective, fair, and practically feasible to implement. While research has highlighted the views of Olympic athletes on anti-doping over the past decade, the experiences and perceptions of Para athletes have not been extensively explored. The purpose of this study was to examine Swedish elite Para athletes
Background: Cartilage oligomeric matrix protein (COMP), an extracellular matrix glycoprotein, is vital in preserving cartilage integrity. Further, its overexpression is associated with the aggressiveness of several types of solid cancers. This study investigated COMP's role in ovarian cancer, exploring clinicopathological links and mechanistic insights.Methods: To study the association of COMP exp
In the dawning era of artificial intelligence (AI), health care stands to undergo a significant transformation with the increasing digitalization of patient data. Digital imaging, in particular, will serve as an important platform for AI to aid decision making and diagnostics. A growing number of studies demonstrate the potential of automatic pre-surgical skin tumor delineation, which could have t
Den här artikeln handlar om hur förtalsbrottet tillämpas på situationer då en person berättar i sociala medier att hen har utsatts för våld eller sexuella övergrepp av en viss person. Inledningsvis diskuteras hur rättighetsskyddet enligt regeringsformen och Europakonventionen inverkar på tillämpningen av förtalsbrottet och de omständigheter som bör beaktas i avvägningen mellan rätten till resp
Background: Growing evidence indicates that young migrants are particularly vulnerable to sexual violence, however most research has focused on instances of sexual violence occurring in conflict zones and during transit. Much less attention has been given to the vulnerabilities to and experiences of sexual violence among young migrants in Europe.Objectives: To understand the scientific evidence re
Background: Well-developed vocabulary skills are crucial for academic success. Students having the language of instruction as a second language and students from lower socioeconomic backgrounds often have lower performance on vocabulary assessments. Teachers play an important role in supporting the vocabulary development of all students, regardless of background and educational needs.Aims: To inve
This article investigates the defence policies of the Nordic and Baltic countries from the perspective of shared security culture. To that end, the article analyses conceptualisations of total defence and resilience in a comparative perspective and inquires into existing and prospective regional cooperation in this area, in order to determine to what degree there exists a common security culture b
In situ gamma-spectrometric measurements were performed at grasslands (45 plots) and forests (6 plots) in the vicinity of the Belarusian nuclear power plant in September–October 2019. The aim of the study was to evaluate the baseline level of ambient dose equivalent rates of gamma radiation from natural radionuclides and 137Cs in the period preceding the commissioning of the NPP. The study reveale
Hydropower is a renewable and reliable energy source that can be utilized to fulfil energy demands and promote energy sustainability. In hydropower plants, Pelton turbines are installed at high-head and low-discharge sites. In Pelton turbines, needle, nozzle, buckets, and splitter are most exposed to silt erosion. An eroded turbine takes more discharge than rated for generating the same amount of
Background: Home haemodialysis (HHD) may be associated with important clinical, social or economic benefits. However, few randomised controlled trials (RCTs) have evaluated HHD versus in-centre HD (ICHD). The relative benefits and harms of these two HD modalities are uncertain. This is an update of a review first published in 2014. This update includes non-randomised studies of interventions (NRSI
A central role for sexual isolation in the formation of new species and establishment of species boundaries has been noticed since Darwin and is frequently emphasized in the modern literature on speciation. However, an objective evaluation of when and how sexual isolation plays a role in speciation has been carried out in few taxa. We discuss three approaches for assessing the importance of sexual
