Sökresultat
Filtrera
Filtyp
Din sökning på "*" gav 530993 sökträffar
Research and development practices in the transnational company: A study of a Norwegian based aluminum company
The Influence of Sea Waves on Offshore Wind Turbine Aerodynamics
The impacts of swells on the atmospheric boundary layer (ABL) flows and by this on the standalone offshore wind turbine (WT) performance are investigated by using large eddy simulations (LES) and actuator-line techniques. At high swell to wind speed ratio, the swell-induced stress reduces the total wind stress resulting in higher wind velocity, less wind shear, and lower turbulence intensity level
Accelerating crystal plasticity simulations using GPU multiprocessors
Crystal plasticity models are often used to model the deformation behavior of polycrystalline materials. One major drawback with such models is that they are computationally very demanding. Adopting the common Taylor assumption requires calculation of the response of several hundreds of individual grains to obtain the stress in a single integration point in the overlying FEM structure. However, a
Moving beyond short-term coping and adaptation
Throughout human history, people have coped with, and adapted to, their environment. This accumulated capacity at local level is increasingly recognized to be critical in improving resilience and transformation. Nevertheless, city dwellers’ coping and adaptive practices are little known, poorly documented and often not taken into account in the work of municipal authorities and aid organizations.
Impact of cardiac dysfunction on health-related quality of life in cirrhotic liver transplant candidates
Objective Cardiac dysfunction, in particular left ventricular diastolic dysfunction, is common in cirrhosis. We aimed to investigate the impact of cardiac dysfunction on health-related quality of life (QoL) in liver cirrhosis. Materials and methods A total of 88 cirrhotic liver transplant candidates with an available echocardiogram and ECG completed the Short form-36 (SF-36) and Fatigue Impact Sca
Smoking and the risk of prostate cancer in the European Prospective Investigation into Cancer and Nutrition
Background: Smoking is not associated with prostate cancer incidence in most studies, but associations between smoking and fatal prostate cancer have been reported. Methods: During 1992 and 2000, lifestyle information was assessed via questionnaires and personal interview in a cohort of 145112 European men. Until 2009, 4623 incident cases of prostate cancer were identified, including 1517 cases of
Increased risk of cirrhosis and hepatocellular cancer during long-term follow-up of patients with biopsy-proven NAFLD.
Abstract Objective. Our aims were to investigate the natural history of biopsy-proven non-alcoholic fatty liver disease (NAFLD) in Sweden, its associated complications, the clinical and biochemical factors associated with more advanced liver disease and the survival rate with a mean follow-up time of 27 years. Material and methods. All subjects participating in the population-based prospective coh
Interfering with histone demethylases in HSCs.
Catalytically Active Silica Nanoparticle-Based Supramolecular Architectures of Two Proteins - Cellobiose Dehydrogenase and Cytochrome c on Electrodes
Artificial nanobiomolecular architectures that follow natural examples in protein assembly become more and more important from basic and applied points of view. Our study describes the investigation on cellobiose dehydrogenase (CDH), cytochrome c (cyt c), and silica nanoparticles (SiNP's) for the construction of fully catalytically active supramolecular architectures on electrodes. We report on in
Conductance Enhancement of InAs/InP Heterostructure Nanowires by Surface Functionalization with Oligo(phenylene vinylene)s
We have investigated the electronic transport through 3 mu m long, 45 nm diameter InAs nanowires comprising a 5 nm long InP segment as electronic barrier. After assembly of 12 nm long oligo(phenylene vinylene) derivative molecules onto these InAs/InP nanowires, we observed a pronounced, nonlinear I-V characteristic with significantly increased currents of up to 1 mu A at 1 V bias, for a back-gate
Sorting cells by size, shape and deformability.
While size has been widely used as a parameter in cellular separations, in this communication we show how shape and deformability, a mainly untapped source of specificity in preparative and analytical microfluidic devices can be measured and used to separate cells.
Inactivation of promoter 1B of APC causes partial gene silencing: evidence for a significant role of the promoter in regulation and causative of familial adenomatous polyposis
Familial adenomatous polyposis (FAP) is caused by germline mutations in the adenomatous polyposis coli (APC) gene. Two promoters, 1A and 1B, have been recognized in APC, and 1B is thought to have a minor role in the regulation of the gene. We have identified a novel deletion encompassing half of this promoter in the largest family (Family 1) of the Swedish Polyposis Registry. The mutation leads to
Standardized marketing strategies in retailing? IKEA’s marketing strategies in Sweden, the UK and China
The role of entrepreneurship education and start-up experience for handling communication and liability of newness
Purpose – The aim of this study is to test the assumption that ability to handle communication and liability of newness (LoN) is enhanced by academic entrepreneurship education and/or previous start‐up experience. Design/methodology/approach – The data collection includes a questionnaire with a total sample of 392 responding entrepreneurs in Sweden. Statistical analyses are made between entrepren
Zero, one, or in between : Evaluation of alternative national and entity-level accounting for bioenergy
Accounting for bioenergy's carbon dioxide (CO2) emissions, as done under the Kyoto Protocol (KP) and European Union (EU) Emissions Trading Scheme, fails to capture the full extent of these emissions. As a consequence, other approaches have been suggested. Both the EU and United States already use value-chain approaches to determine emissions due to biofuels - an approach quite different from that
User Image Mismatch in Anesthesia Alarms: A Cognitive Systems Analysis
In this study, principles of Cognitive Systems Engineering are used to better understand the human–machine interaction manifesting in the use of anaesthesia alarms. The hypothesis is that the design of the machine incorporates built-in assumptions of the user that are discrepant with the anaesthesiologist's self-assessment, creating ‘user image mismatch’. Mismatch was interpreted by focusing on th
Chronic widespread pain is associated with slower cognitive processing speed in middle-aged and older European men
Evidence from clinic-based studies suggests that the fibromyalgia syndrome (FMS) is associated with impairment in cognitive function though the mechanism is unclear. The aim of this analysis was to determine whether there is a similar association between chronic widespread pain (CWP), a cardinal feature of FMS, and impaired cognition in a community setting. Men (n = 3369, 40-79 years) were recruit
Near-infrared spectroscopy for intracoronary detection of lipid-rich plaques to understand atherosclerotic plaque biology in man and guide clinical therapy.
Ischaemic heart disease is the leading cause of death worldwide. The common denominator for plaques causing acute coronary syndrome (ACS) is lipid accumulation, either as a lipid core or lipid pools. An intracoronary imaging device to detect lipid-rich plaques (LRPs) could therefore identify most of the plaques causing ACS and sudden death. Near-infrared spectroscopy combined with intravascular ul
High frequency ultrasound of skin involvement in systemic sclerosis - a follow-up study.
High-frequency ultrasound offers a potential for objective and quantitative assessment of skin thickness and skin echogenicity in systemic sclerosis (SSc). Few studies have however assessed the longitudinal changes of skin involvement using ultrasound. The aim of the study was to investigate changes in skin thickness in early SSc using high frequency ultrasound during one year of follow-up in comp