We study diffusion of cooperation in a two-population game in continuous time. At each instant, the game involves two random individuals, one from each population. The game has the structure of a Prisoner's dilemma where each player can choose either to cooperate (c) or to defect (d), and is reframed within the field of approachability in two-player repeated game with vector payoffs. We turn the g

The clinical success of targeted cancer therapies is limited by the emergence of drug resistance often due to pre-existing tumor genetic heterogeneity and acquired, therapy-induced resistance. Targeted therapies have varied success in addressing metastatic disease, due to their ability to penetrate certain physiological compartments. This paper considers an evolutionary cancer model that incorpora

No abstract in Web of Sci

Climatic fire danger will likely increase because more droughts and heat-waves are caused by climate change. Climate change can shift fires from occurring only rarely to regularly in ecosystems not until now adapted to fire. We applied dynamic vegetation-fire models to investigate these future responses. The future of fire in Mediterranean-type ecosystems depends strongly on changes in vegetation

Geochronologies of intramontane depression (basin) fluvial sedimentation enable to identify through time periods of alluviation and river erosion, and date fault movement. For these purposes the optically stimulated luminescence (OSL) dating has been applied to evaluate and to develop a geochronological framework of river terraces. We study the age of river terrace deposits of the Czarny Dunajec R

This material was evaluated for genotoxicity, repeated dose toxicity, developmental toxicity, reproductive toxicity, local respiratory toxicity, phototoxicity/photoallergenicity, skin sensitization potential, as well as, environmental safety. Data from the suitable read across analog isobornyl acetate (CAS # 125-12-2) show that this material is not genotoxic, provided a MOE> 100 for the repeated d

There has been an increased interest in ways of measuring the value of new therapeutic options in oncology. An example of this in a European context is the ESMO Magnitude of Clinical Benefit Scale (ESMO-MCBS). The purpose of this study is to analyse how the value scales, exemplified with ESMO-MCBS, developed mainly to assist decisions by physicians, relate to other measures of clinical benefit and

Investigating epidemiology of metastatic colon and rectal cancer is challenging, because cancer registries seldom record metastatic sites. We used a population based approach to assess metastatic spread in colon and rectal cancers. 49,096 patients with colorectal cancer were identified from the nationwide Swedish Cancer Registry. Metastatic sites were identified from the National Patient Register

Current manuscript gives a synopsis of tumor heterogeneity related to patient samples analyzed by proteomics, protein expression analysis and imaging mass spectrometry.First, we discuss the pathophysiologocal background of cancer biology as a multifactorial and challenging diseases. Disease pathology forms the basis for protein target selection. Therefore, histopathological diagnostics and grading

Nine species in five genera of the family Axinellidae, including three new species, Axinella badungensis sp. nov., A. ba-linensis sp. nov. and Phycopsis pesgalli sp. nov. are recorded from Indonesian waters within the limits of the Western Coral Triangle province. Descriptions and discussion of those species are presented here. Four new combinations, Pha-kettia arbora (Sim, Kim & Byeon, 1990)

Atmospheric particulate matter is one of the main factors governing the Earth's radiative budget, but its exact effects on the global climate are still uncertain. Knowledge on the molecular-scale surface phenomena as well as interactions between atmospheric organic and inorganic compounds is necessary for understanding the role of airborne nanoparticles in the Earth system. In this work, surface c

Two world-class research facilities, the European Spallation Source, ESS, and the light-source facility MAX-IV, are being built in southern Sweden. They will primarily, when completed, be used for research in the fields of material sciences, life sciences, medicine and pharmacology. Their construction and the operation and maintenance of them for many years will create new business opportunities f

Inthispaper,wedescribeanovelsystemthatidentifiesrelationsbetweentheobjectsextractedfromanimage. We started from the idea that in addition to the geometric and visual properties of the image objects, we could exploit lexical and semantic information from the text accompanying the image. As experimental set up, we gathered a corpus of images from Wikipedia as well as their associated articles. We ext

The massive amounts of text data made available through the Google Books digitization project have inspired a new field of big-data textual research. Named culturomics, this field has attracted the attention of a growing number of scholars over recent years. However, initial studies based on these data have been criticized for not referring to relevant work in linguistics and language technology.

Using the combination of high resolution core level spectroscopy and density functional theory we present adetailed spectroscopic study for all clean and hydrogen covered phases of Ir(100). The results are complementedby an investigation of the hydrogen desorption process from various phases using temperature programmeddesorption spectroscopy and scanning tunneling microscopy. In total, all experi

High-dose melphalan and autologous stem cell transplantation (HDM/ASCT) is widely used in immunoglobulin light chain (AL) amyloidosis, but the benefit is debated mainly because of the high treatment-related mortality (24% in a randomised study comparing HDM/ASCT with oral melphalan/dexamethasone). We report here on the long-term outcome of all patients treated with HDM/ASCT for AL amyloidosis in S