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Background: Human intratumoral T cell infiltrates can be defined by quantitative or qualitative features, such as their ability to recognize autologous tumor antigens. In this study, we reproduced the tumor-T cell interactions of individual patients to determine and compared the qualitative characteristics of intratumoral T cell infiltrates across multiple tumor types. Methods: We employed 187 pai

In the 1920s and 1930s, the Swedish labour market was characterized by strikes and lockouts. Violent confron-tations sometimes occured during these strikes, as striking workers clashed with strikebreakers recruited by the employers. Workers useda variety of protest methods, creating a repertoire of contention including for example bombs and mock trials.One of the more prevalent methods was to “fol

Droughts are often suspected to increase the risk of violent conflict through agricultural production shocks, and existing studies often explore these links through meteorological proxies. In Syria, an alleged agricultural collapse caused by drought is assumed to have contributed to increased migration and the conflict outbreak in 2011. Here we use satellite derived cropland and climate data to st

We have characterized and compared the structures of ergosterol- and cholesterol-containing 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) membranes before and after interaction with the amphiphilic antifungal drug amphotericin B (AmB) using neutron reflection. AmB inserts into both pure POPC and sterol-containing membranes in the lipid chain region and does not significantly perturb the

We investigate error propagation in sliding window decoding of braided convolutional codes (BCCs). Previous studies of BCCs have focused on iterative decoding thresholds, minimum distance properties, and their bit error rate (BER) performance at small to moderate frame length. Here, we consider a sliding window decoder in the context of large frame length or one that continuously outputs blocks in

Even though the European Union has promoted multilingualism for long, it has proven difficult to achieve widespread multilingual language competence beyond English through formal education in Europe. In Sweden, high dropout rates have been recorded in second foreign language (SFL) classes and French is currently the most vulnerable language among the major SFLs with respect to number of pupils and

This paper presents a search for direct top squark pair production in events with missing transverse momentum plus either a pair of jets consistent with Standard Model Higgs boson decay into b-quarks or a same-flavour opposite-sign dilepton pair with an invariant mass consistent with a Z boson. The analysis is performed using the proton–proton collision data at s=13 TeV collected with the ATLAS de

A search is presented for four-top-quark production using an integrated luminosity of 139 fb- 1 of proton–proton collision data at a centre-of-mass energy of 13TeV collected by the ATLAS detector at the LHC. Events are selected if they contain a same-sign lepton pair or at least three leptons (electrons or muons). Jet multiplicity, jet flavour and event kinematics are used to separate signal from

In animal contests, resource value (the quality of a given resource) and resource holding potential (a male's absolute fighting ability) are two important factors determining the level of engagement and outcome of contests. Few studies have tested these factors simultaneously. Here, we investigated whether natural, seasonal differences in cactus phenology (fruit quality) influence interactions bet

The ambrosia fungus Flavodon ambrosius is the primary nutritional mutualist of ambrosia beetles Ambrosiodmus and Ambrosiophilus in North America. F. ambrosius is the only known ambrosial basidiomycete, unique in its efficient lignocellulose degradation. F. ambrosius is associated with both native American beetle species and species introduced from Asia. It remains unknown whether F. ambrosius is s

Theoretical and empirical studies have shown that species radiations are facilitated when a trait under divergent natural selection is also involved in sexual selection. It is yet unclear how quick and effective radiations are where assortative mating is unrelated to the ecological environment and primarily results from sexual selection. We address this question using sympatric grasshopper species

Contaminated ground is a severe problem which is present in many countries, and it is of great importance to find efficient solutions to deal with it. In Sweden, there is a trend in the industry to move towards alternate remediation methods and on that scope in-situ bioremediation has received a lot of attention. The main challenge with in-situ bioremediation is to verify that the treatment has th

The PreProcessor of the ATLAS Level-1 Calorimeter Trigger prepares the analogue trigger signals sent from the ATLAS calorimeters by digitising, synchronising, and calibrating them to reconstruct transverse energy deposits, which are then used in further processing to identify event features. During the first long shutdown of the LHC from 2013 to 2014, the central components of the PreProcessor, th

The PHENIX experiment has measured the spin alignment for inclusive J/ψ→e+e- decays in proton-proton collisions at s=510 GeV at midrapidity. The angular distributions have been measured in three different polarization frames, and the three decay angular coefficients have been extracted in a full two-dimensional analysis. Previously, PHENIX saw large longitudinal net polarization at forward rapidit

The ammonia oxidation reaction over a PtRh binary alloy has been studied with a surface science approach by operando techniques such as near-ambient pressure X-ray photoemission spectroscopy (NAP-XPS) and surface X-ray diffraction (SXRD) combined with mass spectrometry. The article will explore the surface evolution across five different oxygen to ammonia ratios in the millibar regime for two diff

This chapter briefly reviews how bibliometric indicators are used for allocating resources in academia. How these measures can be understood in relation to different evaluation systems is discussed, and various types of applications - including individual level use - are outlined. Furthermore, attention is given to the effect of evaluation in terms of incentives and possible adverse effects. The i

Introduction: due to increasing coverage of antiretroviral therapy (ART), more women living with HIV have improved health condition which also increases their chances of getting pregnant. However, the knowledge about pregnancy among women receiving ART in resource-constrained settings, like Ethiopia, is limited. The aim was to assess factors associated with pregnancy among women living with HIV in

The digital transformation of the retailing industry in recent years has had a profound effect on consumers’ behaviour on a global scale. When shopping and browsing online, consumers are not able to “touch and feel”, which means that product returns are inevitable. The fashion industry has particularly suffered from high return rates, which fluctuate between 30% and 50%. The industry has been stru