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Tissue diagnostics using laser-induced fluorescence

We have performed extensive investigations of laser-induced fluorescence in animal and human tissue aimed at instant tissue characterization. Autofluorescence, as well as specific fluorescence from HPD/DHE and other photosensitizers, has been utilized. The studies have been focused on the demarcation of malignant tumours and atheroscleortic plaques. A nitrogen laser or an excimer-pumped dye laser

Study of SARS-CoV-2 transmission in urban environment by questionnaire and modeling for sustainable risk control

Caused by SARS-CoV-2, COVID-19 has become a severe threaten to society and human health, its epidemic control emerges as long-term issue. A sustainable epidemic and environmental transmission risk control (SEERC) in urban area is urgently needed. This work aims to conduct a new investigation on the transmission risk of SARS-COV-2 as virus/hazardous material through various environmental medias, ro

Promoting the degradation of organic micropollutants in tertiary moving bed biofilm reactors by controlling growth and redox conditions

A novel process configuration was designed to increase biofilm growth in tertiary moving bed biofilm reactors (MBBRs) by providing additional substrate from primary treated wastewater in a sidestream reactor under different redox conditions in order to improve micropollutant removal in MBBRs with low substrate availability. This novel recirculating MBBR was operated on pilot scale for 13 months, a

In situ determination of 137Cs inventory in soil using a field-portable scintillation gamma spectrometer-dosimeter

A new empirical method for in situ determination of the inventory of 137Cs in soil (ACs, kBq m−2) at grasslands and forests using a field-portable NaI(Tl) scintillation spectrometer-dosimeter was developed. The method is based on evaluation of the ambient dose equivalent build-up factor. The practical implementation of the new method with the spectrometer-dosimeter does not require a priori knowle

Novel approach for predicting groundwater storage loss using machine learning

Comprehensive national estimates of groundwater storage loss (GSL) are needed for better management of natural resources. This is especially important for data scarce regions with high pressure on groundwater resources. In Iran, almost all major groundwater aquifers are in a critical state. For this purpose, we introduce a novel approach using Artificial Intelligence (AI) and machine learning (ML)

Influence of operational conditions and wastewater properties on the removal of organic micropollutants through ozonation

The objective of this study was to evaluate the influence of operational conditions and wastewater properties on the removal of pharmaceuticals, contrast media and antibiotics through ozonation, in order to facilitate the optimization of treatment and its implementation on a full scale. Pilot-scale ozone oxidation trials were performed on treated wastewater, before and after post-precipitation, ov

Extraction of natural moisturizing factor from the stratum corneum and its implication on skin molecular mobility

The natural moisturizing factor (NMF) is a mixture of small water-soluble compounds present in the upper layer of the skin, stratum corneum (SC). Soaking of SC in water leads to extraction of the NMF molecules, which may influence the SC molecular properties and lead to brittle and dry skin. In this study, we investigate how the molecular dynamics in SC lipid and protein components are affected by

Related in death? A curious case of a foetus hidden in bishop Peder Winstrup's coffin in Lund, Sweden

When the famous bishop of Lund, Peder Winstrup, died in 1679 he was laid to rest in a family crypt in Lund Cathedral alongside his wife. Following a restoration of the Cathedral in the late 19th century, Peder Winstrup's coffin was moved to the crypt, as the family grave was dismantled. In 2012, a decision was made to move his remains to a different location presenting scientists with an opportuni

Relaxation of electronic excitations in K2GeF6 studied by means of time-resolved luminescence spectroscopy under VUV and pulsed electron beam excitation

Highly crystalline K2GeF6 micropowders were prepared by co-precipitation in the hydrofluoric acid-water-alcohol solution and studied by means of the cathodoluminescence and time-resolved luminescence spectroscopy under synchrotron radiation excitation at 7 K. The nature of various intrinsic emissions was revealed. The luminescence band at 510 nm detected under excitation by photons with the energy

Risk of Rehospitalization and Death in Patients Hospitalized Due to Asthma

Background: Asthma is a heterogeneous inflammatory airway disease that continues to cause considerable morbidity across the world, with poor asthma control leading to hospitalizations. Objective: The present study investigated the risk of rehospitalization, mortality, and the management of patients with asthma who had been hospitalized because of an asthma exacerbation. Methods: National Swedish h

Altered winter conditions impair plant development and yield in oilseed rape

The demand for agricultural products is expected to increase as a result of population growth, changed diets and demands for bioenergy. At the same time, agricultural yields in many regions are expected to be negatively impacted by climate change. Here we show, how altered winter conditions in combination with an extreme weather event impact reproductive development and yield of oilseed rape (Bras

Change patterns of sleep problems predict mental health problems among adolescents : a 10-year cohort study of Chinese Wenchuan earthquake

Background: The predictive effects of change patterns of sleep problems on mental health after a long-term disaster remain poorly known. We examined the change patterns of sleep problems after the Wenchuan earthquake, and tested whether specific sleep-related change patterns could predict mental health problems (posttraumatic stress disorder [PTSD], anxiety, and depression) in the 10 years after W

Evaluating the performance of the OSCORE security protocol in constrained IoT environments

The Constrained Application Protocol (CoAP) is a standard communication protocol for resource-constrained devices in the Internet of Things (IoT). Many IoT deployments require proxies to support asynchronous communication between edge devices and the back-end. This allows (non-trusted) proxies to access sensitive parts of CoAP messages. Object Security for Constrained RESTful Environments (OSCORE)

The screening and evaluation of potential clinically significant HIV drug combinations against the SARS-CoV-2 virus

Spike glycoprotein is essential for the reproduction of the SARS-CoV-2 virus, and its inhibition using already approved antiviral drugs may open new avenues for treatment of patients with the COVID-19 disease. Because of that we analyzed the inhibition of SARS-CoV-2 spike glycoprotein with FDA-approved antiviral drugs and their double and triple combinations. We used the VINI in silico model of ca

A distortional hardening model for finite plasticity

Plastic anisotropy may strongly affect the stress and strain response in metals subjected to multiaxial cyclic loading. This anisotropy evolves due to various microstructural features. We first use simple models to study how such features result in evolving plastic anisotropy. A subsequent analysis of existing distortional hardening models highlights the difference between stress- and strain-drive

Temporal increase in D614G mutation of SARS-CoV-2 in the Middle East and North Africa

Background: Phylogeny construction can help to reveal evolutionary relatedness among molecular sequences. The spike (S) gene of SARS-CoV-2 is the subject of an immune selective pressure which increases the variability in such region. This study aimed to identify mutations in the S gene among SARS-CoV-2 sequences collected in the Middle East and North Africa (MENA), focusing on the D614G mutation,