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Implementation of an Electric Vehicle fire scenario in the Fire Impact Tool
The Fire Impact Tool uses Life Cycle Assessment (LCA) and Environmental Risk Assessment (ERA) methods to assess the local and global environmental impact of the response of the Fire and Rescue Services (FRS) to enclosure fires and vehicle fires. The tool provides examples of fires and allows responder to compare the impact of different extinguishment techniques.This report presents the methodology
Factors most strongly associated with breathlessness in a population aged 50–64 years
Background: Breathlessness is a troublesome and prevalent symptom in the population, but knowledge of related factors is scarce. The aim of this study was to identify the factors most strongly associated with breathlessness in the general population and to describe the shapes of the associations between the main factors and breathlessness.Methods: a cross-sectional analysis of the multicentre popu
Translating climate service into personalized adaptation strategies to cope with thermal stress (ClimApp)
Climate change has increased the frequency and intensity of extreme weather events. Heat waves and cold spells pose a threat to human health, well-being and productivity. The impact of thermal stress depends on not only climate factors, but also individual factors and vulnerability. Current heat wave early warning systems are mainly based on air temperature. It is necessary to extend and improve c
Pathogen-mediated selection in the immune system of rodents : Exploring selection targets, functional effects and trade-offs
Pathogens cause disease and play an important role in shaping evolution of the host immune system. They create pressure on host immunity to evolve in numerous ways, most commonly by increasing divergence between species (positive selection) or increasing polymorphisms within a population (balancing selection). Especially with balancing selection, trade-offs between different traits, for example re
Method—Setups and Protocols for Operando Batteries Experiments at Variable Temperatures Applied to CaxTiS2 and Na3−xV2(PO4)3
In this paper, we present two thermalized setups for in situ operando X-ray diffraction data collection in temperature ranging from 0° to 100 °C: a modified Leriche cell and a coin cell chamber. Both setups proved proper thermalization and representative electrochemistry. While the coin cell chamber may only be used in transmission mode, the modified Leriche cell can also be used in reflection mod
Sweets and other sugary foods - a scoping review for nordic nutrition recommendations 2023
Background: Sweets, chocolate, and sweet bakery products are generally high in energy and added sugar, whereas the levels of essential nutrients and fibre are low. According to sales statistics, the consumption of sweets and chocolate is high in the Nordic and Baltic countries. Objective: This scoping review describes the totality of evidence for the role of sweets and other sugary foods for healt
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Le Covid-19 a déclenché une vague de confinements à travers le monde, contribuant à un grave ralentissement de l’activité économique. Les gouvernements ont réagi en adoptant des mesures budgétaires et monétaires expansionnistes. Nous comparons les résultats sanitaires et économiques de la Suède, généralement considérée comme une exception qui repose davantage sur des recommandations et des ajustem
Etranacogene dezaparvovec gene therapy for haemophilia B (HOPE-B) : 24-month post-hoc efficacy and safety data from a single-arm, multicentre, phase 3 trial
Background: Etranacogene dezaparvovec, the first gene therapy approved for haemophilia B treatment, was shown to be superior to treatment with continuous prophylactic factor IX in terms of bleeding protection 18 months after gene therapy in a phase 3 trial. We report post-hoc 24-month efficacy and safety data from this trial to evaluate the longer-term effects of etranacogene dezaparvovec in indiv
Toward InSAR-intelligence assessment of groundwater resources in time and space
Poor management and excessive pumping of groundwater (GW) resources can lead to a significant decline in GW level, which may result in land deformation and compaction of compressible fine-grained soils within or adjacent to the aquifer. Soil compaction and resulting land deformation may be permanent if the GW level declines beyond the maximum historical stress. In extreme cases, the aquifer may lo
Clinical care advice for monitoring of islet autoantibody positive individuals with presymptomatic type 1 diabetes
Background/Aim: Type 1 diabetes is an autoimmune disease that involves the development of autoantibodies against pancreatic islet beta-cell antigens, preceding clinical diagnosis by a period of preclinical disease activity. As screening activity to identify autoantibody-positive individuals increases, a rise in presymptomatic type 1 diabetes individuals seeking medical attention is expected. Curre
Peace in a Changing Climate : Caring and Knowing the Climate-Gender-Peace Nexus
Enligt forskare och praktiker innebär klimatförändringarna särskilda utmaningar för freden. För att förstå vilka dessa utmaningar är och hur man ska hantera dem måste man ta hänsyn till kön, eftersom både erfarenheter av och processer för fred, samt drivkrafter bakom klimatförändringar är könsbundna. Exempelvis kan kvinnor och män uppleva förhållandena efter en vapenvila på olika sätt, eller så kaScholars and practitioners argue that climate change poses particular challenges for peace. In order to understand what these challenges are and how to tackle them necessitates attention to gender, since experiences and processes of peace are gendered, as are experiences and drivers of climate change. For instance, women and men may experience conditions after a ceasefire differently, or climate h
Epigenetic Fingerprint of the SARS-CoV-2 Infection in the Lung of Lethal COVID-19
Antibiotic Prescribing in Dental Medicine—Best Practices for Successful Implementation
With rising rates of antimicrobial resistance throughout the world, it is time to revisit antibiotic prescribing policies and practices, and dentistry is an important area for focused intervention, as it accounts for up to 15% of all antimicrobial prescriptions. In this narrative review, we have analyzed the current state of the knowledge, attitudes, and practice regarding antimicrobial use among
Re : Liu et al., Effectiveness and safety of opioids on breathlessness and exercise endurance in patients with chronic obstructive pulmonary disease: A systematic review and meta-analysis of randomised controlled trials
Schisandrin B Suppresses Colon Cancer Growth by Inducing Cell Cycle Arrest and Apoptosis : Molecular Mechanism and Therapeutic Potential
Colon cancer is among the most lethal and prevalent malignant tumors in the world, and the lack of effective therapies highlights the need for novel therapeutic approaches. Schisandrin B (Sch B), a lignan extracted from the fruit ofSchisandra chinensis, has been reported for its anticancer properties. However, to date, no studies have been done to characterize the exact molecular mechanisms underl
Allergic Contact Dermatitis to Linalool Hydroperoxides : Pitfalls in the Diagnostic Process—Findings from a Repeated Open Application Test Study
Background: Increasing trends of oxidized linalool contact allergy have been reported. However, the impact of reactivity and dose in eliciting allergic contact dermatitis caused by linalool hydroperoxides is insufficiently investigated. Objectives: To perform repeated open application tests (ROATs) using the real-world concentrations of linalool hydroperoxides in patients and control participants.
Reducing the Environmental Impact of Large Battery Systems with Conductive Electric Road Systems—A Technical Overview
A radical transformation of the transport industry is required in order to achieve a fossil-fuel-free vehicle fleet and reach the greenhouse gas emissions goals. Electrification plays a crucial role in this radical process. An electric road system (ERS) is a road that supplies power to electric vehicles as they drive on it, offering numerous advantages. These include an extended driving range, dec