Filtyp
Context: Prostate cancer (PCa) is one of the most common human malignancies and arises through genetic and epigenetic alterations. Epigenetic modifications include DNA methylation, histone modifications, and microRNAs (miRNA) and produce heritable changes in gene expression without altering the DNA coding sequence. Objective: To review progress in the understanding of PCa epigenetics and to focus
An unconventional system for separate collection of food waste was investigated through evaluation of three full-scale systems in the city of Malmö, Sweden. Ground food waste is led to a separate settling tank where food waste sludge is collected regularly with a tank-vehicle. These tank-connected systems can be seen as a promising method for separate collection of food waste from both households
Background About 30% of cases of chronic lymphocytic leukaemia (CLL) carry quasi-identical B-cell receptor immunoglobulins and can be assigned to distinct stereotyped subsets. Although preliminary evidence suggests that B-cell receptor immunoglobulin stereotypy is relevant from a clinical viewpoint, this aspect has never been explored in a systematic manner or in a cohort of adequate size that wou
Several studies have found protective effects of low/moderate (hereafter 'light') alcohol consumption compared with 'abstinence' on mortality, health and wage. Some of these studies have been criticised because former drinkers have been included among the abstainers, which may overstate the protective effect of light alcohol consumption. It has also been proposed, but not shown, that the commonly
Background: The majority of non-syndromic colorectal cancers (CRCs) can be described as a complex disease. A two-stage case-control study on CRC susceptibility was conducted to assess the influence of the ancestral alleles in the polymorphisms previously associated with nutrition-related complex diseases. Methods: In stage I, 28 single nucleotide polymorphisms (SNPs) were genotyped in a hospital-b
Popular Abstract in Swedish Epigenetik handlar om hur avläsning av informationen i arvsmassan kan styras och nedärvas mellan cellgenerationer. Förmågan att kunna ändra genuttrycksmönster som svar på signaler från omgivningen och sedan bibehålla dessa genom efterföljande celldelningar ligger till grund för korrekt funktion av vävnaderna och organen som våra kroppar är uppbyggda av. Samtliga sjukdomPrecise spatial and temporal regulation of gene expression programs is a prerequisite for multicellular life. Since the discovery of DNA as the carrier of genetic information, a key question in biology has been how these hard coded instructions are read and regulated to maintain cellular and organismal homeostasis. Understanding the mechanisms and processes governing gene and genome regulation are
En artikel om betydelser av ljud och tystnad för studier och välbefinnande.
Background. Foam and gauze are two types of wound fillers used for negative pressure wound therapy (NPWT). Differences in the wound healing effects of foam and gauze have been observed clinically. The aim of the present study was to examine the effects of NPWT on the wound bed using foam and gauze. Methods. A porcine peripheral wound model was treated with NPWT at 0, -75 mmHg, or -125 mmHg for 72
This paper summarises a RACR solution of The TTC 2015 Model Execution Case. RACR is a metacompiler library for Scheme. Its most distinguished feature is the seamless combination of reference attribute grammars and graph rewriting combined with incremental evaluation semantics. The presented solution sketches how these integrated analyses and rewriting facilities are used to transform fUML Activity
The forefield of the Solheimajokull outlet glacier, South Iceland, has a variety of glacial landforms and sediments that are products of late Holocene and modern glacier oscillations. Several sets of moraine ridges reflect past ice front positions and river-cut sedimentary sections provide information about past environments. Here, we describe sediments and landforms deposited during the late Holo
The Cd rich part of the Cd-Pd phase diagram was reassessed by means of synthesis and single crystal and powder X-ray diffraction. The region contains two phases that have been reported to have substantial compositional widths, Cd11Pd2 and Cd4Pd. The phase Cd11Pd2 that has previously been reported to be a disordered gamma-brass crystallizing is space group P (4) over bar 3m is here shown to crystal
