Doxorubicin (DOX), a potent and broad-spectrum antineoplastic agent, causes an irreversible, cumulative and dose-dependent cardiomyopathy that ultimately leads to congestive heart failure. The mechanisms responsible for DOX cardiotoxicity remain poorly understood, but seem to involve mitochondrial dysfunction on several levels. Epigenetics may explain a portion of this effect. Since mitochondrial

Although the benefits of moderate intake of red wine in decreasing incidence of cardiovascular diseases associated to hypercholesterolemia are well recognized, there are still widespread misconceptions about its effects on the hypercholesterolemia-related cognitive impairments. Herein we investigated the putative benefits of regular red wine consumption on cognitive performance of low-density lipo

Our aesthetic response to the Universe, and the complexity of concepts through which we understand it, are inherently bound together in how we meaningfully interpret its nature. Over millennia the abstracted and intangible concepts of science have been developed and communicated through a rich array of representations across a variety of modes. The interpretation of such representations is a compl

The sharing economy is a novel way of distributing physical resources facilitated by online platforms where temporary access is given to goods owned by peers or organisations. It has become prominent in urban areas where a large accumulation of resources in close proximity and the ubiquity of information and communications technology enable it to grow. Its emergence has had various impacts on exis

Diffusion MRI uses magnetic field gradients to sensitize the signal to the random motion of spins. In addition to the prescribed gradient waveforms, background field gradients contribute to the diffusion weighting and thereby cause an error in the measured signal and consequent parameterization. The most prominent contribution to the error comes from so-called ‘cross-terms.’ In this work we presen

Models where dark matter is a part of an electroweak multiplet feature charged particles with macroscopic lifetimes due to the charged-neutral mass split of the order of pion mass. At the Large Hadron Collider, the ATLAS and CMS experiments will identify these charged particles as disappearing tracks, since they decay into a massive invisible dark matter candidate and a very soft charged Standard-

Exercise can improve health among adolescents with depression. Understanding facilitators for and barriers to maintaining exercise among adolescents with depression may increase adherence to exercise and consequently improve health. The aim was to explore adolescents’ experiences of facilitators for and barriers to maintaining exercise after a group-based exercise intervention for depression. Inte

The idea of this special issue on Spoken language in time and across time emerged at an international symposium on this topic that we organised at Lund University on 20 September 2019. The purpose of the symposium was to celebrate important past and present achievements of spoken language research as well as past and present corpora available for such research. Some speakers reported on academic a

Introduction: Occupational balance (OB) is an important concept in occupational therapy and is considered as an essential component of health and well-being. The aim of this study was to show differences in OB and quality of life (QoL) between mothers of children with cerebral palsy (CP) and typically developing children. Methods: Thirty-six mothers of children with CP and 36 mothers of typically

I anmälan presenteras huvuddragen i boken följtav en kort kommentar om hur studien kan användas inom ramen för detfinansrättsliga ämnet. I anslutning därtill presenteras även en personlig reflektionöver bokens förtjänster och brister.

Hovering insects are divided into two categories: ‘normal’ hoverers that move the wing symmetrically in a horizontal stroke plane, and those with an inclined stroke plane. Normal hoverers have been suggested to support their weight during both downstroke and upstroke, shedding vortex rings each half-stroke. Insects with an inclined stroke plane should, according to theory, produce flight forces on

This paper describes a case study at an automotive company with the purpose of developing an economically based decision support tool, for strategic decision about whether to chose grinding or shaving as a finishing method in gear manufacturing. In the study different cost models are compared regarding input parameters in alignment with the required input data required to make a decision. With the

In 2010, the Swedish Civil Contingencies Agency (MSB) announced a “vision zero” of zero fire deaths in Sweden by 2050. Studies into fire deaths have identified that certain risk groups, including but not limited to older people, are overrepresented in fire death statistics in Sweden. The MSB has developed guidelines for how individualised fire safety (IFS) can be implemented in local communities f

Low-grade inflammation and arterial stiffness are key factors in the development of vascular aging. However, the interplay between arterial stiffness and inflammation for cardiovascular (CV) disease is unclear. Aortic pulse wave velocity (aPWV) and the inflammatory markers, high-sensitivity C-reactive protein (CRP) and orosomucoid, were measured in 2710 participants (median age: 72 years). These p