On α-synuclein cooperativity in lipidic membranes binding
α-Synuclein is an intrinsically disordered protein implied in still not-well-known healthy function and also found as the main component of aggregates in Lewy bodies and Lewy neurites, hallmarks of the Parkinson’s disease. In both of cases, the interaction with lipid membranes is crucial. In this study we propose the investigation of the interaction between α-Synuclein and model systems made of DO
