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Popular Abstract in Swedish Alltsedan expansionen av den högre utbildningen tog fart i Sverige, i slutet av 60-talet, har universitet och högskolor arbetat för att utveckla utbildningskvaliteten. Detta har bland annat gjorts genom satsningar på policys som reglerar exempelvis arbete med kursvärderingar, mångfald, och kurs- och utbildningsplaner. Satsningar har också gjorts på pedagogisk utbildningThe focus in this thesis is to explore theoretical perspectives and strategies for academic development, particularly in a research-intensive university. The purpose is to investigate academic development that aims to support and influence individual academic teachers and groups of teachers, in the different social collegial contexts that they work in, here called microcultures. Building on litera

A measurement of the differential cross-section for the inclusive production of isolated prompt photons in pp collisions at a center-of-mass energy root s = 7 TeV is presented. The measurement covers the pseudorapidity ranges vertical bar eta vertical bar < 1.37 and 1.52 <= vertical bar eta vertical bar < 2.37 in the transverse energy range 45 <= E(T) < 400 GeV. The results are based on an integra

The biodegradability of dissolved organic carbon (DOC) in different fractions from the forest floor was studied. Soil leachate (SI, the soil solution in macropores which is freely drained from forest floor after rainfall), the soil matrix solution (SMS, the soil solution in meso-/micropores of the soil matrix), and soil water extracts (SWE) from two different beech forest floors were compared. Zer

Inflammation is a response to injury or pathogen invasion. A large proportion of the bodie's immune system is centred in the gastrointestinal tract (GI). Prolonged inflammatory conditions of the GI have been suggested to increase the risk for developing colon cancer. The cysteinyl leukotrienes (CysLTs), LTC4, LTD4 and LTE4 are inflammatory mediators that can bind to four known receptors, two of wh

In recent years, the 'river basin as a management unit' approach has been adopted as a solution to water management. The situation between Swaziland, Mozambique and South Africa regarding managing the water resources of the Incomati, Maputo, and Umbeluzi shared river basins is an interesting case that might need a different approach. These rivers flow downstream to the Maputo estuary where their w

We present a conceptual model for supercontinent cycles in the Proterozoic-Phanerozoic Eons. It is based on the repetitive behavior of C and Sr isotopes in marine carbonates and U–Pb ages and εHf of detrital zircons seen during the Neoproterozoic-Paleozoic and Paleoproterozoic Eras, respectively. These records are considered to reflect secular changes in global tectonics, and it is hypothesized th

Popular Abstract in Swedish Socioekonomiska mönster av övervikt och fetma i Skåne, Sverige I världen idag är fetma och övervikt ett av de största hoten mot människors goda hälsa. Den här avhandlingen har försökt beskriva och öka kunskapen om hur olika faktorer, som levnadsvillkor och levnadsvanor, bidragit till ökningen av övervikt och fetma i befolkningen. Övervikt och fetma ökar risken för en rOverweight and obesity are major social and public health concerns globally. The obesity epidemic is caused by a widespread chronic energy imbalance between high-energy intake and low-energy expenditure, but this mechanism appears to be modified by a number of other biological, behavioral, and social factors that interact in a complicated manner. It has become a great challenge to understand the e

Participating in physical activity promotes physical and mental health. Children with physical disabilities are not as physically active as other children. They tend to participate in lower intensity physical activity, choose more passive activities with less variety and have more sedentary time. The overall aim of this thesis was to gain knowledge about participation in physical activities, to i

Multifunctional proteins, which play a critical role in many biological processes, have typically evolved through the recruitment of different domains that have the required functional diversity. Thus the different activities displayed by these proteins are mediated by spatially distinct domains, consistent with the specific chemical requirements of each activity. Indeed, current evolutionary theo

In poeciliid fish the male anal fin has been transformed into a gonopodium, an intromittent organ required for internal fertilization. Elevated testosterone levels induce metamorphosis of a subset of anal fin rays to grow and form the specialized terminal structures of the gonopodium. The molecular mechanisms underlying these processes are largely unknown. Here, we investigated whether retinoic ac

A dye-binding method using Acid Orange 12 was investigated regarding its suitability for the quantification of available lysine, as a means of monitoring the Maillard reaction in skim milk powders. The method was evaluated by analyzing a wide range of milk powders produced by three different drying methods and stored under various conditions. A pilot-scale freeze-dryer, spray-dryer and drum-dryer

Myocardial perfusion scintigraphy (MPS) is a clinically useful noninvasive imaging modality for diagnosing patients with suspected coronary artery disease. By utilizing gated MPS, the end diastolic volume (EDV) and end systolic volume (ESV) can be measured and the ejection fraction (EF) calculated, which gives incremental prognostic value compared with assessment of perfusion only. The aim of this

Snow, water, ice, and permafrost are showing evidence of substantial change in the Arctic, with large variations among different geographical areas. As a result of these changes, some habitats and their associated ecosystems are expanding, while others are undergoing rapid contraction. The warming of the Arctic cryosphere is limiting the range for cold-adapted biota, and less specialized taxa incl

A series of 1-phenyl-3-(1-phenylethyl)urea derivatives were identified as novel and potent complement inhibitors through structural modification of the original compound from high-throughput screening. Various analogues (7 and 13-15) were synthesized and identified as complement inhibitors, with the introduction of a five- or six-carbon chain (7c, 7d, 7k, 7I, and 7o) greatly improving their activi

We study a one-dimensional random walk whose expected drift depends both on time and the position of a particle. We establish a non-trivial phase transition for the recurrence vs. transience of the walk, and show some interesting applications to Friedman's urn, as well as showing the connection with Lamperti's walk with asymptotically zero drift.

Systemic instigation is a process by which endocrine signals sent from certain tumors (instigators) stimulate BM cells (BMCs), which are mobilized into the circulation and subsequently foster the growth of otherwise indolent carcinoma cells (responders) residing at distant anatomical sites. The identity of the BMCs and their specific contribution or contributions to responder tumor growth have bee

Expression of mutant huntingtin (htt) protein has been shown to cause metabolic imbalance in animal models of Huntington disease (HD). The pathways involved are not fully understood but dysfunction of both the hypothalamus and brown adipose tissue (BAT) has been implicated. Here we show that targeted expression of mutant HTT in the hypothalamus leads to loss of the A13 dopaminergic cell group loca