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Hip and Spine in Cerebral Palsy

Popular Abstract in Swedish Cerebral Pares (CP) är en övergripande benämning på ett rörelsehinder som orsakas av en skada som inträffat i en omogen hjärna. Graden av rörelsehinder varierar. Det föds cirka 200 barn årligen i Sverige med CP. Hög muskelspänning i kombination med muskelförsvagning och svårigheter att ändra ställning kan leda till att höften går ur led (höftledsluxation) och att ryggenAbstract Background: Children with cerebral palsy (CP) have an increased risk of scoliosis, contractures including windswept hip deformity (WS), and hip dislocation. In 1994, a follow-up program and registry for children and adolescents with CP (CPUP) was initiated in Sweden to allow the early detection and prevention of hip dislocations and other musculoskeletal deformities. Purpose: To analyze t

CysLT1R Antagonists Inhibit Tumor Growth in a Xenograft Model of Colon Cancer.

The expression of the inflammatory G-protein coupled receptor CysLT1R has been shown to be upregulated in colon cancer patients and associated with poor prognosis. The present study investigated the correlation between CysLT1R and colon cancer development in vivo using CysLT1R antagonists (ZM198,615 or Montelukast) and the nude mouse xenograft model. Two drug administration regimens were establish

On the mechanisms that limit oxygen uptake during exercise in acute and chronic hypoxia: role of muscle mass

Peak aerobic power in humans ((V) over dot(O2), peak) is markedly affected by inspired O-2 tension (F-IO2). The question to be answered in this study is what factor plays a major role in the limitation of muscle peak. (V) over dot(O2) in hypoxia: arterial O-2 partial pressure (P-a,(O2)) or O-2 content (C-a,C-O2)? Thus, cardiac output (dye dilution with Cardio-green), leg blood flow (thermodilution

Visualisation on supersonic flow over backward-facing step with or without roughness

At Mach number 3.4, visualisation experiments of flowover backward-facing step (BFS) with or without roughness band attached on upstream wall are carried out via traditional schlieren and newly developed nano-tracer-based planar laser scattering (NPLS). The time-averaged flow characteristic of the reattachment region and the instantaneous rich structures of the redeveloping boundary layer in the s

Stress analysis around a through crack shaped void in a single crystal copper strip coated on an infinitely stiff material using molecular dynamics

A small rectangular strip of fcc Cu, containing a through crack on the nanoscale and subjected to loading under displacement control, is simulated using molecular dynamics (MD). The geometry is highly constrained and chosen to mimic that of a thin film between two stiff layers. The Lennard Jones pair potential is used for the inter-atomic forces. The centrally placed crack-shaped void is created b

Amplitudes, rates, periodicities and causes of temperature variations in the past 2485 years and future trends over the central-eastern Tibetan Plateau

Amplitudes, rates, periodicities, causes and future trends of temperature variations based on tree rings for the past 2485 years on the central-eastern Tibetan Plateau were analyzed. The results showed that extreme climatic events on the Plateau, such as the Medieval Warm Period, Little Ice Age and 20th Century Warming appeared synchronously with those in other places worldwide. The largest amplit

Road Traffic Noise - Factors modifying its relation to annoyance and cardiovascular disease

Popular Abstract in Swedish Minst en miljon friska levnadsår går förlorade varje år på grund av trafikbuller i Västeuropa. Buller stör vardagsaktiviteter och sömn, samt har kopplats samman med flera andra dåliga effekter på livskvalitet och hälsa, bland annat ökad risk för högt blodtryck och hjärtinfarkt. Vi vet från tidigare forskning att de dåliga effekterna av trafikbuller kan ändras av socialaTraffic noise causes annoyance and sleep disturbance and has been linked with several other adverse effects on life quality and health, including increased risk of hypertension and myocardial infarction. Conservative estimates assume that at least one million healthy life years are lost every year from traffic related noise in the western part of Europe. We know from earlier studies that the adver

Identification and energy calibration of hadronically decaying tau leptons with the ATLAS experiment in pp collisions at root s=8 TeV

This paper describes the trigger and offline reconstruction, identification and energy calibration algorithms for hadronic decays of tau leptons employed for the data collected from pp collisions in 2012 with the ATLAS detector at the LHC center-of-mass energy root s = 8 TeV. The performance of these algorithms is measured in most cases with Z decays to tau leptons using the full 2012 dataset, cor

ASPECTS OF FLUID THERAPY: An experimental study of the effects of systemic inflammation, microvascular permeability, blood pressure and plasma volume

Adequate circulating blood volume is a prerequisite for circulatory stability. Fluid therapy aims at correcting hypovolaemia, and is an important part of the haemodynamic management of perioperative and critically ill patients. The efficacy of plasma volume substitution largely depends on the pharmacological properties of the colloid solutions used. However, according to the 2-pore theory for tran

Building Physics Tools: Needs, Use and the Lack of Use in the Building Process. Modelling Non-Isothermal Moisture Flow and Frost Penetration

Popular Abstract in Swedish Trots utvecklingen inom materialvetenskap, datorkapacitet och byggnadsteknik, fortsätter fel relaterade till byggnadsfysik att inträffa i våra byggnader. Dessa byggnadsfel spänner mellan att byggnader inte möter kraven på energianvändning till att byggnader orsakar hälsoproblem hos de människor som vistas i byggnaden till följd av att de utsätts för kemikalier eller bioDespite advances in material science, computers and building technology, building failures related to building physics continue to occur. These failures range from a building not meeting its energy use target to a building causing people to become ill from exposure to various chemicals or biological organisms. These failures cost society considerable amounts of money each year and many of these fa

Statistical modelling of spike libraries for simulation of extracellular recordings in the cerebellum

Brain machine interfaces with chronically implanted microelectrode arrays for signal acquisition require algorithms for successful detection and classification of neural spikes. During the design of such algorithms, signals with a priori known characteristics need to be present. A common way to establish such signals is to model the recording environment, simulate the recordings and store ground t

Relationship between commuting and health outcomes in a cross-sectional population survey in southern Sweden

Background: The need for a mobile workforce inevitably means that the length of the total work day (working and traveling time) will increase, but the health effects of commuting have been surprisingly little studied apart from perceived stress and the benefits of physically active commuting. Methods: We used data from two cross-sectional population-based public health surveys performed in 2004 an

Scaling analyses of high-resolution dye tracer experiments

Four unsaturated solute transport experiments with different water fluxes were conducted in a Hele-Shaw cell filled with uniform sand. The transport of the dye tracer used was recorded with a camera and the dye concentration was calculated using image analysis. The concentrations fields were analysed in terms of time moments and converted into vertical solute transport velocity V. Both mean value

Recent discoveries widen the basis for future research in Alzheimer´s disease.

Abstract. Intended as food for thought this revue offers a general orientation on Alzheimer’s disease (AD) with comments on the brain changes and clinical features. But more importantly, it points out recent research findings which may offer new alleys for AD research pertinent to the etiology and pathogenesis of AD and alternatives to the so far rather unfruitful and costly amyloid research trail