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Socio-economic and occupational risk factors for gastric cancer : A cohort study in Sweden

The effects of socio-economic/occupational factors on gastric cancer at various subsites (including corpus, cardia and unspecified cancers) are not well known. To investigate this issue, we carried out a follow-up study on the economically active Swedish population, based on the Swedish Family-Cancer Database. We calculated standardized incidence ratios and 95% confidence intervals for different o

Obstructive sleep apnea syndrome in siblings : an 8-year Swedish follow-up study

BACKGROUND: Understanding the genetic transmission of obstructive sleep apnea syndrome (OSAS) will help clinicians identify patients at risk and offer opportunities for intervention and treatment at specialist clinics.OBJECTIVE: To estimate familial risk of hospitalization for OSAS in the adult population of Sweden, and to determine if there are any differences by age and sex.DESIGN, SETTING, AND

Synthesis and SAR Studies of Antibacterial Peptidyl Derivatives Based upon the Binding Site of Human Cystatin C

BACKGROUND: Antibacterial peptidyl derivative - Cystapep 1, was previously found to be active both against antibiotic-resistant staphylococci and streptococci as well as antibiotic-susceptible strains of these species. Therefore, it is a promising lead compound to search for new antimicrobial peptidomimetics.OBJECTIVES: We focused on identifying structural elements that are responsible for the bio

Nationwide comparison of long-term survival and cardiovascular morbidity after acute aortic aneurysm repair in patients with and without type 2 diabetes

Objective: Epidemiologic data indicate decreased risk for development, growth, and rupture of abdominal aortic aneurysm (AAA) among patients with type 2 diabetes mellitus (DM). We therefore evaluated mortality and cardiovascular morbidity after acute repair of AAA in diabetic and nondiabetic patients. Methods: In this nationwide observational cohort study of patients registered in the Swedish Vasc

Toward the optimization of an e-tongue system using information visualization : A case study with perylene tetracarboxylic derivative films in the sensing units

The wide variety of molecular architectures used in sensors and biosensors and the large amount of data generated with some principles of detection have motivated the use of computational methods, such as information visualization techniques, not only to handle the data but also to optimize sensing performance. In this study, we combine projection techniques with micro-Raman scattering and atomic

Uncertainty of determination of 158Tb in the RBMK nuclear reactor waste

The activity of 158Tb was measured in waste samples from the Ignalina NPP Unit I RBMK-1500 reactor using gamma-ray spectrometry. The origin of 158Tb and the other observed gamma-ray emitters has been studied by using SCALE 6.1 modeling and comparing radionuclide ratios in the RBMK-1500 radioactive waste. The results of the calculation of the massic activity of gamma-ray emitters were used for inte

Neglected Values of Major Water Engineering Projects: Ecosystem Services, Social Impacts, and Economic Valuation

Major water infrastructure projects like dams can provide substantial benefits such as food and drinking water security, hydropower generation, and flood control. But these benefits may come at a (too) high cost of large scale ecological alterations or adverse social impacts such as involuntary resettlements. If these costs are neglected, an investment decision will hardly be efficient. In this ch

Cardiac Remodeling in Aortic and Mitral Valve Disease - a Simulation Study with Clinical Validation

BACKGROUND: Remodeling is an important long-term determinant of cardiac function throughout the progression of heart disease. Numerous biomolecular pathways for mechanosensing and transduction are involved. However, we hypothesize that biomechanical factors alone can explain changes in myocardial volume and chamber size in valve disease.METHODS: A validated model of the human vasculature and the f

Compact three-dimensional U(1) gauge theory reexamined

Convincing evidence of a nonvanishing string tension in the continuum limit of compact three-dimensional U(1) gauge theory is presented. It is based on Monte Carlo measurements of Wilson loops on a 323 lattice at =2.0 and 2.2. The observed string tensions at these couplings are consistent with the Polyakov theory. Also, a very clean signal of a string vibrational contribution to the potential is o

Template-Assisted Scalable Nanowire Networks

Topological qubits based on Majorana Fermions have the potential to revolutionize the emerging field of quantum computing by making information processing significantly more robust to decoherence. Nanowires are a promising medium for hosting these kinds of qubits, though branched nanowires are needed to perform qubit manipulations. Here we report a gold-free templated growth of III-V nanowires by

Pterin-pigmented nanospheres create the colours of the polymorphic damselfly Ischnura elegans

Animal colours commonly act as signals for mates or predators. In many damselfly species, both sexes go through a developmental colour change as adults, and females often show colour polymorphism, which may have a function in mate choice, avoidance of mating harassment and camouflage. In the blue-tailed damselfly, Ischnura elegans, young males are bright green and turn blue as they reach maturity.

Dally-like protein, a new Drosophila glypican with expression overlapping with wingless

Proteoglycans, the molecules of extracellular matrix, carry a highly negative charge due to their glycosaminoglycan (GAG) chains and large volumes. They were considered to play a secondary role in activities like cell division, adhesion, blood coagulation, etc. until the importance of their sugar chains in the fibroblast growth factor (FGF) signalling was discovered (Science 252 (1991) 1705; Cell

A Drosophila neurexin is required for septate junction and blood-nerve barrier formation and function

Septate and tight junctions are thought to seal neighboring cells together and to function as barriers between epithelial cells. We have characterized a novel member of the neurexin family, Neurexin IV (NRX), which is localized to septate junctions (SJs) of epithelial and glial cells. NRX is a transmembrane protein with a cytoplasmic domain homologous to glycophorin C, a protein required for ancho

Tena, a Drosophila gene related to tenascin, shows selective transcript localization

We report the identification and molecular characterization of tena*, a Drosophila gene located at 11A6-9 on the X-chromosome. The deduced protein of 782 amino acids contains eight tenascin-type EGF-like repeats not described in Drosophila before, but lacks the fibronectin type III repeats and the fibrinogen homology present in the vertebrate tenascin molecules. Tena codes for a large transcript w

Search for Higgs boson pair production in the γγWW∗ channel using pp collision data recorded at √s = 13 TeV with the ATLAS detector

Searches for non-resonant and resonant Higgs boson pair production are performed in the γγWW∗ channel with the final state of γγℓνjj using 36.1 fb - 1 of proton–proton collision data recorded at a centre-of-mass energy of s=13 TeV by the ATLAS detector at the Large Hadron Collider. No significant deviation from the Standard Model prediction is observed. A 95% confidence-level observed upper limit

Anisotropic growth is achieved through the additive mechanical effect of material anisotropy and elastic asymmetry

Fast directional growth is a necessity for the young seedling; after germination, it needs to quickly penetrate the soil to begin its autotrophic life. In most dicot plants, this rapid escape is due to the anisotropic elongation of the hypocotyl, the columnar organ between the root and the shoot meristems. Anisotropic growth is common in plant organs and is canonically attributed to cell wall anis

Sifting segregation of ideal blends in a two-hopper tester : Segregation profiles and segregation magnitudes

The main aims of this work were: 1) to increase the understanding of the segregation process that occurs during a segregation test that follows the ASTM sifting segregation procedure, and 2) to understand the effect of powder load, fines mass fraction and particle diameter ratio on the segregation of ideal blends. Binary blends of microcrystalline cellulose particles (mean diameter ranging from 16