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Att leva med cancer som äldre - livskvalitet och upplevelse av mening

Hur påverkas livssituationen för äldre som drabbas av cancer? Oftast blir sjukdomen ytterligare en belastning i en redan komplex situation. I denna artikel sammanfattas resultat från en undersökning av en grupp äldre (över 75 år) personer med cancer. Livskvaliteten påverkades mest hos yngre äldre, men gruppen är heterogen och personerna kräver ett individuellt bemötande.

Diabetic retinopathy, visual acuity, and medical risk indicators: a continuous 10-year follow-up study in Type 1 diabetic patients under routine care

The objective of this study was to describe incidence and progression of diabetic retinopathy in relation to medical risk indicators as well as visual acuity outcome after a continuous follow-up period of 10 years in a Type 1 diabetic population treated under routine care. The incidence and progression of retinopathy and their association to HbA(1c), blood pressure, urinary albumin, serum creatini

Skuld och oskuld : barnamord och barnkvävning i rättslig diskurs och praxis omkring 1680–1800

Syftet med denna avhandling är att analysera hur berättelser om skyldiga och oskyldiga mödrar konstruerades under perioden ca. 1680-1800. De två brottskategorierna barnamord och barnkvävning har undersökts. Källmaterialet har huvudsakligen bestått av protokoll från hovrätten, underrätter och sockenstämmor. Jag har klarlagt vilka omständigheter som utreddes vid brottsutredningarna och fick betydelsThe objective of this thesis is to analyse how judicial texts concerning guilty and innocent mothers were constructed during the period of c. 1680-1800. The two crimes of infanticide and overlaying have been examined. Source materials have primarily consisted of proceedings from the appeals court, courts of first instance, and parish meetings. The aim has been to survey the judicial discourse, tha

A Simple Slab Temperature Model

The model presented in this paper has been used for predicting the slab core temperature in several applications at The Danish Steel Works Ltd. The model has the advantages that it is simple and only contains a minimum of physical parameters, which makes it easy use and adapt to slab temperature measurements. The model has been verified using 11 data sets covering three different slab thicknesses

Prediction of bone loss using biochemical markers of bone turnover.

The association between baseline levels of eleven bone turnover markers and 5-year rate of bone density change was prospectively studied in a population-based sample of 601 75-year-old women. Several bone formation and resorption markers as well as urinary osteocalcin were modestly correlated to rate of bone density change. Introduction Prediction of bone loss by bone turnover markers (BTMs) has b

Natural killer T cell subsets and regulation of autoimmune diabetes

This thesis is focused on natural killer (NK) T cells. NKT cells recognize lipids and glycolipids, rather than peptides, in the contents of the antigen presenting molecule CD1d. NKT cells have a surface phenotype reminiscent of memory cells, and have been shown to rapidly produce large amounts of cytokines, such as IL-4 and IFN-gamma, upon activation. Because of their rapid response to activation,

Use of nanoparticles in capillary and microchip electrochromatography

Applications of nanoparticles are of rising interest in separation science, due to their favorable surface-to-volume ratio as well as their applicability in miniaturization. A stationary phase with large surface area in combination with an electroosmotic flow-driven system has great potential in a highly efficient separation system. This review covers the use of various nanoparticles as stationary

Tender or not tender: Test-retest repeatability of pressure pain thresholds in the trapezius and deltoid muscles of healthy women

Objective: To examine the test-retest repeatability of pressure pain thresholds in the shoulder muscles of healthy women. Design: Four experimental sessions (days 1, 3, 28, 30), each including 4 consecutive pressure pain threshold measurements at 10-minute intervals. Subjects: Twenty-four healthy female volunteers, mean age 42 years. Methods: Two examiners measured pressure pain thresholds bilater

Hög tid att pröva hypotermi i behandlingen av slaganfall

There is a revived clinical interest in hypothermia as a neuroprotective intervention in brain ischemia. This originates from the experimental finding that hypothermia of only 3 degrees C-4 degrees C below normal body temperature completely abolishes neuronal damage from an ischemic insult that is lethal in normothermia. The idea that hypothermia protects cells from ischemic damage mainly by lower

A study of exercise-induced microalbuminuria in type I (insulin-dependent) diabetes mellitus

Microalbuminuria is thought to be an important prognostic factor in diabetes mellitus. To study the influence of changes in blood pressure on the development of microalbuminuria during exercise, two exercise tests were carried out. A total of 32 insulin dependent diabetic men whose age at onset was less than 30 years, mean duration of diabetes 14 years (range 7 to 21) and mean age 29 years (range

Effect of alpha-ketoglutarate (AKG) on mineralisation, morphology and mechanical endurance of femur and tibia in turkey

The aim of this study was to determine the influence of alpha-ketoglutarate (AKG) on volumetric bone density, geometrical and mechanical properties of femur and tibia in farm turkeys. All animals were kept under standard rearing conditions with constant access to water and appropriate feed, supplied in accordance with the stage of production cycle. Bone samples were collected 14 weeks after beginn

Corneal surface changes in keratoconjunctivitis sicca. Part I: the surface proper. A non-contact photomicrographic in vivo study in the human cornea

Purpose To describe corneal surface changes in keratoconjunctivitis sicca (KCS). Methods In all 23 patients with KCS were examined with the slit lamp and photographed by non-contact photomicrography. Results Without staining, grey surface cells and small epithelial cysts were visible. Application of fluorescein sodium resulted in two types of micropunctuate (15-30 mum) staining, a nonfluorescent (