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Flow cytometry evaluation of red blood cells mimicking naturally occurring ABO subgroups after modification with variable amounts of function-spacer-lipid A and B constructs.

BACKGROUND: Kodecytes bearing synthetic blood group A and B antigens are increasingly being used in transfusion laboratories as serologic mimics of red blood cell (RBC) A(weak) and B(weak) subtypes. The aim of this study was to compare the flow cytometry profile of kodecytes with native ABO subgroups. STUDY DESIGN AND METHODS: A series of A/B kodecytes, each with decreasing A or B antigen express

Med datorn spåras själens boning

Den mänskliga intelligensen går inte att isolera till enbart hjärnans aktiviteter. Tanken gror och frodas i social gemenskap och kultur. Men var finns då själen? Filosofen Ingar Brinck funderar kring den amerikanske komplexitetsforskaren John L Castis bok The Cambridge Quintet.

Hematopoietic reconstitution by multipotent adult progenitor cells: precursors to long-term hematopoietic stem cells

For decades, in vitro expansion of transplantable hematopoietic stem cells (HSCs) has been an elusive goal. Here, we demonstrate that multipotent adult progenitor cells (MAPCs), isolated from green fluorescent protein (GFP)-transgenic mice and expanded in vitro for >40-80 population doublings, are capable of multilineage hematopoietic engraftment of immunodeficient mice. Among MAPC-derived GFP+CD4

Backward Compatibility of the COST259 Directional Channel Model

We consider the COST259 directional channel model (DCM) in relation to other existing channel models. The COST259 DCM is a general model for the mobile radio channel that includes narrowband power (field strength), power delay profiles, and directions of arrival. For comparison purposes, it is desirable that the channel models forming the basis of earlier simulations are contained as special cases

Evaluation of an algorithm for arterial lumen diameter measurements by means of ultrasound.

We have developed an algorithm for arterial luminal diameter measurement by means of ultrasound and evaluated the algorithm on agar vessel phantoms and in vivo. The algorithm utilises relative threshold detection on the inner slopes of the arterial walls before the resolution is improved by solving the equation of a straight line between the samples around the threshold value. Further, correction

Failure disjoint paths

Given a weighted directed graph where some arcs can fail while others are reliable, we aim to compute a shortest pair of failure-disjoint paths. If a reliable arc is used by both paths, its cost is counted only once. We present a polynomial time algorithm to solve the problem.

Liberty, Law and Leviathan. Of Being Free from Impediments by Artifice

The argument in this paper is that Hobbes’ theory of freedom in Leviathan allows for four ways of being free to act – corporal freedom by nature, freedom from obligation by nature, the freedom to disobey, and the freedom of no-rule – each corresponding to a particular absence, some of which make sense only in the civil state. Contrary to what some have claimed, this complexity does not commit Hobb

Solar symbolism in Gebel el Silsila’

Continuing on the topic presented in the last number of Ancient Planet Online (2012/2), which introduced the topic of pseudo script in the ancient quarries at Gebel el Silsila in Egypt, this article will look closer at one group of quarry marks and their symbolic association with solar religion during the Ptolemaic and early Roman periods.

A novel approach to measure local cerebral haematocrit using MRI.

The percentage blood volume occupied by red blood cells is known as haematocrit. While it is straightforward to measure haematocrit in large arteries, it is very challenging to do it in microvasculature (cerebral haematocrit). Currently, this can only be done using invasive methods (e.g. PET), but their use is very limited. Local variations in cerebral haematocrit have been reported in various bra