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Sentinel lymph node biopsy staging for cutaneous malignant melanoma of the head and neck.

Conclusion Sentinel lymph node biopsies (SLNBs) can be performed safely and with reasonable accuracy in HNM patients. The outcome provides important prognostic information concerning DFS and further treatment. However, one must recognize that SLNB is a multidisciplinary procedure with a learning curve for all. Objectives To evaluate efficacy of performing SLNBs in a series of consecutive patients

Empirical studies of financial asset returns

This dissertation aims at understanding differences in rates of returns on financial assets, both in the cross-section and over time. It contains four chapters. The first paper is "Non-separable preferences and risk aversion: Results from the UK". Due to poor empirical support of the Consumption Capital Asset Pricing Model it has been suggested that the model should be specified as being non-separ

A multicentre, randomised, controlled, open-label pilot study on the feasibility of discontinuation of adalimumab in established patients with rheumatoid arthritis in stable clinical remission.

Treatment with tumour necrosis factor (TNF) blockers, once started as therapy for rheumatoid arthritis (RA), is usually continued indefinitely. The aim of this trial was to assess the possibility of discontinuing treatment with adalimumab (ADA) while maintaining remission in patients with RA with established disease in stable remission on combination therapy with ADA and methotrexate (MTX).

Apolipoprotein M affecting lipid metabolism or just catching a ride with lipoproteins in the circulation?

Apolipoprotein M (apoM) is a novel apolipoprotein found mainly in high-density lipoproteins (HDL). Its function is yet to be defined. ApoM (25 kDa) has a typical lipocalin beta-barrel fold and a hydrophobic pocket. Retinoids bind apoM but with low affinity and may not be the natural ligands. ApoM retains its signal peptide, which serves as a hydrophobic anchor to the lipoproteins. This prevents ap

Contentious Politics Studies : Forskningsfältet social och politisk konfrontation på frammarsch i Skandinavien

In the last decade or so an increasing number of researchers in Scandinavia have become interested in the research field of contentious politics studies (CPS). The result has been a growing number of publications focusing on political contention. We have now reached the point where international research networks are being set up. Several interesting workshops and book projects are underway unders

Sustainable Development in the Context of Education; Swedish Realities and Russian Potential

The goal of this paper is to discuss current problems of education for sustainable development, i.e. a global educational innovation that is actively growing in the new century. In Sweden, which has extensive experience in ecological education, education for sustainable development is considered a national model for the creation of the foundation for SD. In Russia, difficulties exist in defining a

Förort i fokus - interventioner för miljoner : nordisk forskning om interventioner i "utsatta" bostadsområden : en kunskapsöversikt

De utsatta bostadsområdena har under årens lopp varit föremål för ett varierande tvärvetenskapligt intresse med inriktning allt ifrån arkitektur, byggteknik och allmänna kommunikationer, till samhällsvetenskapliga studier av bostadspolitikens effekter: befolkningssammansättningar, demokrati, segregation, osv. Forskningsfältet är således i sig mångfasetterat och kan sägas spegla olika perspektiv på

High-Level GPU Programming: Domain-Specific Optimization and Inference

When writing computer software one is often forced to balance the need for high run-time performance with high programmer productivity. By using a high-level language it is often possible to cut development times, but this typically comes at the cost of reduced run-time performance. Using a lower-level language, programs can be made very efficient but at the cost of increased development time. Re

Motivation och metoder. Två ingredienser i förbättringsarbete enligt Ständiga Förbättringar - Kaizen

Smågruppsverksamhet och ett systematiskt användande av förbättringsverktyg brukar räknas till förutsättningarna för en varaktig förbättringsprocess. Det räcker emellertid inte med att bilda grupper och utbilda i förbättringsverktyg, det måste finnas en motivation hos medarbetarna att vara aktivt delaktiga i förbättringsarbetet. I denna avhandling presenteras en studie där medlemmar i förbättringsg

Elastic wave scattering by a three-dimensional inhomogeneity in an elastic half space

In this paper we will consider scattering of elastic waves in a half space. The half space is an isotropic, linear and homogeneous medium except for a finite inhomogeneity. The T-matrix method (also called the “extended boundary condition method” or “null field approach”) is extended to derive expressions for the elastic field inside the half space and the surface field on the interface. The assum