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Sputum culture yields after antibiotic therapy – a retrospective cohort study

ObjectiveSputum cultures can guide antibiotic therapy, particularly in severe pneumonia or when resistant pathogens are suspected. However, data on how prior and ongoing antibiotic exposure affects microbial detection are limited. This study aimed to evaluate this impact, stratified by timing and route of administration.MethodsIn- and outpatients from nine hospitals in Skåne, Sweden, who submitted

Revealing memory mechanisms in active vision through EEG-eye movement coregistration

Contemporary experimental psychology is shifting away from constrained laboratory settings to tasks that more closely resemble real-world behavior. Traditional experiments often present stimuli at fixed screen locations, which restricts the use of active vision involving eye movements integral to the neural processes underlying perception, attention, and memory. Recent research has highlighted the

Overcoming the Limitations of Forward Osmosis and Membrane Distillation in Sustainable Hybrid Processes Managing the Water–Energy Nexus

Energy-efficient and cost-effective water desalination systems can significantly replenish freshwater reserves without further stressing limited energy resources. Currently, the majority of the desalination systems are operated by non-renewable energy sources such as fossil fuel power plants. The viability of any desalination process depends primarily on the type and amount of energy it utilizes a

Channel Orthogonalization With Reconfigurable Surfaces : General Models, Theoretical Limits, and Effective Configuration

We envision a future in which multi-antenna technology effectively exploits the spatial domain as a set of non-interfering orthogonal resources, allowing for flexible resource allocation and efficient modulation/demodulation. We may refer to this paradigm as orthogonal space-division multiplexing (OSDM). On the other hand, reconfigurable intelligent surface (RIS) has emerged as a promising technol

Between green and safety : navigating sustainability and public health risks in growing media

Production and use of growing media involve a trade-off between sustainability and public health. We claim that a paradigm shift is needed, focusing on properties supporting environmental sustainability and human health, with a holistic approach involving One Health expertise. We use Legionella in growing media, soil, and gardening as an example to highlight key knowledge gaps.

Towards the Development of an Intelligent Control for LED lighting with Solar Energy and Energy Storage for a Jogging Track in the Countryside

Our research aims to develop an intelligent control system for optimizing the operation of lighting systems for a jogging track in the countryside by using adaptive control methods, and optimization of built-in lighting control. Through this, lighting systems will be optimized, energy consumption will be minimized and the lighting system will be adapted to be able to handle a larger amount of loca

Growth Hormone Improves Ovarian Follicle Health in Premature Ovarian Failure Mice by Reducing Apoptosis : (GH Improves Ovarian Follicle Health in POF Mice by Reducing Apoptosis)

Premature ovarian failure (POF) is a perplexing condition in women characterized by cessation of oocyte production in the ovaries. Despite numerous proposed causes for the development of POF, the actual cause of the most POF cases remains unknown. Given that POF significantly affects fertility and is a devastating diagnosis for women, there is an urgent need for the development of new therapies ai

Do standard weather conditions and flower density affect the results of butterfly monitoring schemes? A field test in three bio-geographic regions in Europe

Butterflies and moths have often been suggested as suitable indicators for monitoring environmental effects on biodiversity, land use changes and management practices, and many butterfly monitoring schemes are established and run in Europe. In these monitoring programmes, the field counts are only carried out when certain, standard weather conditions considered favourable for butterflies are met.

Experiments and Large Eddy Simulation of Supersonic Combustion in the Small-Scale Flight Experiment

Supersonic combustion is a critical area of research for advancing high-speed flight technologies, particularly for the development of scramjet engines for hypersonic vehicles. This study employs Finite Rate Chemistry (FRC) Large Eddy Simulation (LES) together with different experimental techniques to study the supersonic flow and thermochemical processes in the Small Scale Flight Experiment (SSFE

Rare MTNR1B variants causing diminished MT2 signalling associate with elevated HbA1c levels but not with type 2 diabetes

Aims/hypothesis: An intronic variant (rs10830963) in MTNR1B (encoding the melatonin receptor type 2 [MT2]) has been shown to strongly associate with impaired glucose regulation and elevated type 2 diabetes prevalence. However, MTNR1B missense variants have shown conflicting results on type 2 diabetes. Thus, we aimed to gain further insights into the impact of MTNR1B coding variants on type 2 diabe

Securing reconfigurable scan networks against data sniffing and data alteration attacks

It is common for a system integrator to make use of third party intellectual property (IP) blocks from multiple vendors in the design of a circuit. These IPs may include test features, known as instruments, which are connected to a reconfigurable scan network, such as an IEEE Std. 1687 (IJTAG) network, for efficient on-chip integration and communication.Using third party instruments this way becom

Model-based animal cognition slips through the sequence bottleneck

In a recent article in TiCS, Lind and Jon-And [1] argued that the sequence memory of animals constitutes a cognitive bottleneck, the ‘sequence bottleneck’, and that mental simulations require faithful representation of sequential information. They therefore concluded that animals cannot perform mental simulations, and that behavioral and neurobiological studies suggesting otherwise are best interp

Secure and efficient sharing of on-chip resources

Semiconductors use on-chip components, referred to as instruments, for test, debugging, firmware programming, configuration and other important functions. The instruments are needed to ensure proper device operation, however, they may be exploited by an adversary in an attack. With many different actors involved in semiconductor development and manufacturing, it becomes important to restrict acces