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Burden of malignant mesothelioma in China during 1990-2019 and the projections through 2029

ObjectiveTo provide the most up-to-date data on the burden of malignant mesothelioma (MM) and the projections through 2029 in China.MethodsData on patients diagnosed with MM from China during 1990-2019 were obtained from the Global Burden of Disease (GBD) 2019 database, including annual cases and deaths data and age-standardized rates of incidence, mortality, and disability-adjusted life-years (DA

Informing Static Mapping and Local Scheduling of Stream Programs with Trace Analysis

Due to their natural and inherent way of capturing concurrency, dataflow descriptions of stream programs have seen prevalent usage in fields such as video processing, networks and scientific computing. They are often deployed on manycore, heterogeneous and distributed architectures. Despite robust research on the topic, obstacles still exist in evaluating the performance of stream programs accurat

Deep learning-based auditory attention decoding in listeners with hearing impairment

This study develops a deep learning method for fast auditory attention decoding (AAD) using electroencephalography (EEG) from listeners with hearing impairment. It addresses three classification tasks: differentiating noise from speech-in-noise, classifying the direction of attended speech (left vs. right) and identifying the activation status of hearing aid noise reduction (NR) algorithms (OFF vs

Diagnostic Yield From a Nationwide Implementation of Precision Medicine for all Children With Cancer

PURPOSE: Several studies have indicated that broad genomic characterization of childhood cancer provides diagnostically and/or therapeutically relevant information in selected high-risk cases. However, the extent to which such characterization offers clinically actionable data in a prospective broadly inclusive setting remains largely unexplored.METHODS: We implemented prospective whole-genome seq

Cross-cultural insights from two global mental health studies: self-enhancement and ingroup biases

This commentary highlights two cross-cultural issues identified from our global mental health (GMH) research, RECOLLECT (Recovery Colleges Characterisation and Testing) 2: self-enhancement and ingroup biases. Self-enhancement is a tendency to maintain and express unrealistically positive self-views. Ingroup biases are differences in one’s evaluation of others belonging to the same social group. Th

Global area boom for greenhouse cultivation revealed by satellite mapping

Greenhouse cultivation has been expanding rapidly in recent years, yet little knowledge exists on its global extent and expansion. Using commercial and freely available satellite data combined with artificial intelligence techniques, we present a global assessment of greenhouse cultivation coverage and map 1.3 million hectares of greenhouse infrastructures in 2019, a much larger extent than previo

We Overfeed Our Heroes Until They Explode. A public artwork forty years in the making

Text discussing the 40-year history of the artwork We Overfeed Our Heroes Until They Explode. Originally created as an unsanctioned stencil painting by American artists John Fekner and Don Leicht in Lund, Sweden, in 1984, the work was recently revisited by Fekner together with American artist Brad Downey as part of a commissioned art project for LundART. A central point raised in the text is the d

Multi-objective Optimization and GIS to Improve Climate Change Induced Disaster Risk Management in Africa

We live in an era that suffers from climate change issues, not least disaster risks induced by climate change. While measures, such as proper evacuation plans, are required to reduce the negative impacts of disasters when they hit, actions should also be taken to reduce climate change effects by e.g. increasing the use of renewable energies or proper urban land-use allocation, where climate change

El Robaperas (The Pear Thief)

With a point of departure in the creation of an unsanctioned street installation in Granada, Spain, in 2005 - which colloquially became known by residents in its vicinity as "El Robaperas" (English: "The Pear Thief") - this essay considers some of the central characteristics of street art. It further discusses some of the conditions under which urban environs may become places for autonomous inter

Brief admission by self-referral for individuals with self-harm and suicidal ideation : a qualitative study based on focus groups exploring relatives' experiences

PURPOSE: Brief Admission by self-referral (BA) is a standardized crisis-management intervention for individuals with self-harm and risk for suicide. This study explored relatives' experiences of BA. Relatives' perspectives may contribute to an increased understanding of the effects of BA given the relatives' role as support and informal caregivers as well as being co-sufferers.METHODS: Fourteen re

GC-biased gene conversion conceals the prediction of the nearly neutral theory in avian genomes

BACKGROUND: The nearly neutral theory of molecular evolution predicts that the efficacy of natural selection increases with the effective population size. This prediction has been verified by independent observations in diverse taxa, which show that life-history traits are strongly correlated with measures of the efficacy of selection, such as the dN/dS ratio. Surprisingly, avian taxa are an excep

Biased Inference of Selection Due to GC-Biased Gene Conversion and the Rate of Protein Evolution in Flycatchers When Accounting for It

The rate of recombination impacts on rates of protein evolution for at least two reasons: it affects the efficacy of selection due to linkage and influences sequence evolution through the process of GC-biased gene conversion (gBGC). We studied how recombination, via gBGC, affects inferences of selection in gene sequences using comparative genomic and population genomic data from the collared flyca

Sex-biased gene expression, sexual antagonism and levels of genetic diversity in the collared flycatcher (Ficedula albicollis) genome

Theoretical work suggests that sexual conflict should promote the maintenance of genetic diversity by the opposing directions of selection on males and females. If such conflict is pervasive, it could potentially lead to genomic heterogeneity in levels of genetic diversity an idea that so far has not been empirically tested on a genomewide scale. We used large-scale population genomic and transcri