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PM 2/21 : Methods for assessing the effects of plant protection products on biodiversity

Lunds universitet fick i uppdrag av Kemikalieinspektionen att kartlägga och beskriva ansatser till metoder som bedömer indirekta effekter av växtskyddsmedel på individer och populationer och studier som utvärderar om nuvarande riskbedömningsmetoder är tillräckliga för att bedöma direkta effekter av växtskyddsmedel på biologisk mångfald. Uppdraget utfördes i två delar. För det första inventerade viLund University was commissioned by the Swedish Chemicals Agency to map and describe emerging methodologies that assess the indirect impact of plant protection products on nontarget organism individuals and populations, and studies that evaluates if current risk assessment methodologies are sufficient to assess direct effects of plant protection products on biodiversity. The commission was perform

Effect of BCG and allogeneic tumour cells on adenovirus type 12 tumorigenesis in mice

HAMSTERS and mice inoculated at birth with tumour viruses have been used in studies of the prophylactic effects of various treatments during the latent period. The incidence of primary tumours in hamsters infected at birth with SV40 is reduced if the virus is inoculated during the latent period1-3. Similar administration of adenovirus type 12 also inhibited the induction of tumours by SV404; this

Higher concordance of PD-L1 expression between biopsies and effusions in epithelioid than in nonepithelioid pleural mesothelioma

BACKGROUND: Malignant mesothelioma (MM) is a therapy-resistant tumor, often causing an effusion. Drugs targeting the programmed cell death 1 (PD-1)/programmed cell death ligand 1 (PD-L1) pathway have shown promising results, but assessment of PD-L1 expression to select patients for therapy has mainly been performed on histologic tissue samples. In a previous study, we showed that MM effusions are

Acute systemic LPS-exposure impairs perivascular CSF distribution in mice

BACKGROUND: The exchange of cerebrospinal (CSF) and interstitial fluid is believed to be vital for waste clearance in the brain. The sleep-dependent glymphatic system, which is comprised of perivascular flow of CSF and is largely dependent on arterial pulsatility and astrocytic aquaporin-4 (AQP4) expression, facilitates much of this brain clearance. During the last decade, several observations hav

Analysis and design of recovery behaviour of autonomous-vehicle avoidance manoeuvres

Autonomous vehicles allow utilisation of new optimal driving approaches that increase vehicle safety by combining optimal all-wheel braking and steering even at the limit of tyre–road friction. One important case is an avoidance manoeuvre that, in previous research, for example, has been approached by different optimisation formulations. An avoidance manoeuvre is typically composed of an evasive p

A technical workforce for regional industrial development? Origin and dispersion of graduates from the technical secondary schools in Malmö and Borås 1855–1930

This article connects to the discussion on skills and knowledge during the early industrialisation. It focuses on how two out of four technical secondary schools in Sweden (Malmö and Borås) lived up to their aims communicated by politicians and other stakeholders: to provide emerging industries and crafts in their regions with technicians and to prepare for studies at the Technological Institute.

Complex Eigenvalue Splitting for the Dirac Operator

We analyze the eigenvalue problem for the semiclassical Dirac (or Zakharov–Shabat) operator on the real line with general analytic potential. We provide Bohr–Sommerfeld quantization conditions near energy levels where the potential exhibits the characteristics of a single or double bump function. From these conditions we infer that near energy levels where the potential (or rather its square) look

Application of lean methods into design process of large power transformers

The paper presents application of lean engineering methods at design process re-engineering. Lean principles are harder to implement in an one-of-a-kind production environment rather than in an environment of a serial production, where there are almost no changes during production process. There are considerable differences in value-added activities that characterize lean production on one hand an

Eco-evolutionary perspectives on emergence, dispersion and dissolution of historical Dutch commons

Historical commons represent self-governed governance regimes that regulate the use and management of natural and man-made shared resources. Despite growing scientific interests, analyses of commons evolution and temporal dynamics are rare and drivers of change (birth, adaptation, dissolution) remain obscure. We apply an interdisciplinary approach and address these issues from an eco-evolutionary