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The growth-promoting polyamines are polybasic compounds that efficiently enter cancer cells by as yet incompletely defined mechanisms. Strategies to inhibit their internalization may have important implications in the management of tumor disease. Here, we show that cellular binding and uptake of polyamines are inhibited by a single chain variable fragment anti-heparan sulfate (HS) antibody. Polyam

The life chart offers rich information that provides a broader picture of the lives of women who have experienced abuse. Life charts could be useful for nurses identifying women in general psychiatric care who have experienced abuse. Despite experiences of abuse and stressful events during childhood, there were only a few indications of them receiving support in the life charts. Many of the women

The paper discusses the generally limited of use of animal bones in Swedish medieval archaeology and the potential of osteological remains as a source of information about social, ideological and economic conditions in the past. Results from analysis of animal bones from the quarter Blekhagen in Lund are used as examples of how osteological remains can be used to identify social and economic condi

CREB3L2, a member of the CREB3 family of transcription factors, spans >120 kbp and is composed of 12 exons. We characterized a widely expressed transcript of CREB3L2 generated by an intronic polyadenylation site in intron 4 of the gene. It could be translated to a CREB3L2 variant which is localized both in the nucleus and the endoplasmatic reticulum. The protein retains the N-terminal transactivat

We use simulations to investigate the effect of sampling frequency on common dependent variables in eye-tracking. We identify two large groups of measures that behave differently, but consistently. The effect of sampling frequency on these two groups of measures are explored and simulations are performed to estimate how much data are required to overcome the uncertainty of a limited sampling frequ

The dorsal-side-up body posture of standing quadrupeds is maintained by coordinated activity of all limbs. Somatosensory input from the limbs evokes postural responses when the supporting surface is perturbed. The aim of this study was to reveal the contribution of sensory inputs from individual limbs to the posture-related modulation of pyramidal tract neurons (PTNs) arising in the primary motor

Instruments related to work are commonly illuminated from an ill-health perspective. The need for a concise and useable instrument in workplace health promotion governed the aim of this paper which is to present the development process and quality assessment of the Work Experience Measurement Scale (WEMS). A survey, using a questionnaire based on established theories regarding work and health, and

Liberalismen är under förändring. Traditionellt var liberalismen en politisk position som hävdade den enskildes rätt mot staten eller majoriteten. Friheten att uttrycka sina politiska åsikter, organisera sig politiskt eller utöva sin religion sågs som demokratins kärna. Liberalismen värnade ofta gränsen mellan det privata och det offentliga samt individens rättigheter gentemot staten och kollektiv