Predicting in vivo therapeutic efficacy of probiotics in a mouse model of Multiple Sclerosis, based on a novel in vitro Peyer’s Patch cell culture system
There is a great interest in trying to pin-point strain specific effects of probiotics on the immune system. The present study compared desirable immunomodulatory properties of newly isolated, novel probiotic strains of different species in a mouse Peyer’s Patch (PP) cell model in vitro, mainly focusing on their ability to affect the population of CD4+FoxP3+ regulatory T cells (Treg), and in incre