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Drug Dependent Circadian Variations in AV-nodal Properties During Atrial Fibrillation

The heart rate during atrial fibrillation (AF) is highly dependent on the conduction properties of the atrioventricular (AV) node, which can be affected using β-blockers or calcium channel blockers, often chosen empirically. Thus, characterization of the AV nodal conduction properties could contribute to personalized treatment of AF. We have created a mathematical network model of the AV node wher

Identification and validation of NFIA as a novel prognostic marker in renal cell carcinoma

Prognostic tools are an essential component of the clinical management of patients with renal cell carcinoma (RCC). Although tumour stage and grade can provide important information, they fail to consider patient- and tumour-specific biology. In this study, we set out to find a novel molecular marker of RCC by using hepatocyte nuclear factor 4A (HNF4A), a transcription factor implicated in RCC pro

Impact of pulp chemical composition and fiber morphology on hygroexpansion and strength properties of kraftliner

Kraftliner is the unbleached pulp used in the outermost layer of corrugated cardboard. Like other types of paper, it is produced from wood chips as a raw material. Kraftliner is known for its high tensile strength, tear resistance, compressive strength, etc., making it suitable for packaging material for heavy objects. When paper is exposed to moisture, there is usually a dimensional change within

Hand-arm vibration : Swedish carpenters' perceptions of health and safety management

Background: Workers in the construction industry are highly exposed to vibration from handheld equipment, which can have negative effects on the nerves and blood vessels in the hands. Employers in this industry often fail to comply with legislation regarding vibration exposure. Aims: To assess carpenters' perceptions of proactive health and safety (H&S) management regarding hand-arm vibration

"It is something that gives us hope" : Lived experience among parents to children with cerebral palsy who are non-ambulant of the phenomenon physical activity, with or without the use of a novel dynamic standing device

INTRODUCTION: Regular physical activity confers health benefits for all. Parents commonly want their children to be physically active, and want to be physically active themselves, but children with cerebral palsy (CP) who are non-ambulant face challenges, and they need support to be physically active. Dynamic standing in the novel motorized assistive device Innowalk has positive effects in childre

Arbetsterapeutiska interventioner och deras påverkan på aktivitet och delaktighet för vuxna med schizofreni - en litteraturstudie

Bakgrund: Majoriteten av personer med schizofreni upplever begränsningar relaterat till aktivitet och delaktighet i vardagliga aktiviteter. Symtombilden består till stor del av positiva och negativa symtom och en bristande sjukdomsinsikt. Det råder begränsad evidens kring hur arbetsterapeutiska interventioner påverkar aktivitet och delaktighet för personer med schizofreni. Syfte: Att kartlägga arbBackground: Most people with schizophrenia experience limitations related to activity and participation in everyday activities. The symptoms largely consist of positive and negative symptoms and a lack of disease insight. There is limited evidence on how occupational therapy interventions affect people with schizophrenia. Aim: To map occupational therapy interventions that affect activity and part

Deformation dependence of magnetic dipole strength below 4 MeV in doubly even rare earth nuclei

We show: (1) In the presence of the pair correlation the M1 transition strength calculated in the deformed oscillator model has a dependence on the quadrupole deformation parameter δ which is considerably stronger than linear and, in fact, it varies quadratically with δ in the limit of small deformation; (2) The deformation dependence in samarium isotopes calculated using the quasiparticle random

Introduction : Images in the Making

In the book’s introductory chapter long-held assumptions concerning archaeological art and images are addressed and challenged, particularly representationalism, and new ways to approach and understand them are offered. Specifically, it is argued that art and images continuously emerge in processes of making and engagement, both in the past and in the present. Hence, art and images are always in m

Parental Leave Reforms in South Korea, 1995–2021: Policy Translation and Institutional Legacies

This article aims to explore how policy translation and institutional legacies have shaped South Korean parental leave policies between 1995 and 2021. It draws on a document analysis of central political documents and interviews with a number of key policy actors in South Korea. The findings show that reforms of parental leave policies were implemented according to four major rationales: maternityThis article aims to explore how policy translation and institutional legacies have shaped South Korean parental leave policies between 1995 and 2021. It draws on a document analysis of central political documents and interviews with a number of key policy actors in South Korea. The findings show that reforms of parental leave policies were implemented according to four major rationales: maternity

Predicting Turns in Proteins with a Unified Model

Motivation: Turns are a critical element of the structure of a protein; turns play a crucial role in loops, folds, and interactions. Current prediction methods are well developed for the prediction of individual turn types, including α-turn, β-turn, and γ-turn, etc. However, for further protein structure and function prediction it is necessary to develop a uniform model that can accurately predict

Predictors of loss to follow-up among adult tuberculosis patients in Southern Ethiopia : a retrospective follow-up study.

BackgroundLoss to follow-up (LTFU) from tuberculosis (TB) treatment and care is a major public health problem as patients can be infectious and also may develop a multi-drug resistant TB (MDR-TB). The study aimed to assess whether LTFU differs by the distance TB patients travelled to receive care from the nearest health facility.MethodsA total of 402 patient cards of TB patients who received care

Mitigating Product and Packaging Damage in the Supply Chain

I en alltmer instabil global ekonomi är kostnadseffektivitet och eliminering av onödiga utgifter avgörande för överlevnad inom företagsvärlden. Förpackning och transport av produkter är potentiella områden för sådana utgifter och kan utgöra en betydande brist i den moderna försörjningskedjan. Denna rapport syftar till att ge en nyanserad förståelse för utmaningarna med att bedriva verksamhet över Amid an increasingly unstable global economy, cost-efficiency and elimination of unnecessary expenses are critical for survival in the corporate world. The packaging and transportation of products present potential areas for such expenses and can constitute a significant flaw in the modern supply chain. This report seeks to provide a nuanced understanding of the challenges involved in conducting b

Quantitative neuroimaging measures of myelin in the healthy brain and in multiple sclerosis

Quantitative magnetic resonance imaging (MRI) techniques have been developed as imaging biomarkers, aiming to improve the specificity of MRI to underlying pathology compared to conventional weighted MRI. For assessing the integrity of white matter (WM), myelin, in particular, several techniques have been proposed and investigated individually. However, comparisons between these methods are lacking

Antenna Arrays for Dual-Frequency Harmonic Radar Application

The aim of this thesis is to design two patch antenna arrays for dual-frequency harmonic radar application, one for the transmitter and the other for the receiver. The arrays are used to track the Bogong moth that migrates from the countryside to the Australian Alps during spring. The tracking is done at the radar by operating the transmitter at one frequency and the receiver at twice the frequenc

Response to dietary l-glutamine supplementation in weaned piglets : A serum metabolomic comparison and hepatic metabolic regulation analysis

A novel metabolomic method based on gas chromatography-mass spectrometry was applied to investigate serum metabolites in response to dietary Gln supplementation in piglets. Sixteen, 21-d-old pigs were weaned and assigned randomly to 2 isonitrogenous diets: 1) Gln diet, which contained 1% L-Gln (as-fed basis), and 2) control diet, which contained LAla to make this diet isonitrogenous with the Gln d

The Storage Location Assignment Problem An optimized simulated annealing algorithm - solving the storage location assignment problem with correlated batched orders

The main topic of this thesis is the storage location assignment problem, which can also be seen as a traveling salesman problem. The objective is to find the shortest path between items to be picked at a medium-sized warehouse. Orders come in batches consisting of items that will be assembled in-house. Therefore, it is essential to pick up all the items contained in the batch before they are drop