BackgroundWithin the ambulance service, assessment and referral of patients, especially those with non-urgent conditions, is a difficult and complicated task. Studies indicate that 12 to 20 percent of all patients are subjected to non-conveyance and discharged at the scene. There is lack of knowledge of what characterizes conveyed and non-conveyed patients. The aim of this study was to explore non

Analyzes research and innovation in the European Union against the backdrop of the COVID pandemic, Brexit, global challenges and a changing international landscape.

Social desirability may cause spurious relations in self-rating measures. The present study sought to disentangle socially desirable responding and content in the relation between measures of personality traits and well-being. Social desirability was operationalized as the evaluative factor (the tendency to react to evaluative content in questionnaire items). We collected self- and peer-ratings of

BRAF inhibitors (BRAFi) selectively target oncogenic BRAFV600E/K and are effective in 80% of advanced cutaneous malignant melanoma cases carrying the V600 mutation. However, the development of drug resistance limits their clinical efficacy. Better characterization of the underlying molecular processes is needed to further improve treatments. We previously demonstrated that transcription of PTEN is

Background: RORγt is a transcription factor that enables elaboration of Th17-associated cytokines (including IL-17 and IL-22) and is proposed as a pharmacological target for severe asthma. Methods: IL-17 immunohistochemistry was performed in severe asthma bronchial biopsies (specificity confirmed with in situ hybridization). Primary human small airway epithelial cells in air liquid interface and p

According to an increasingly popular view known as non-doxasticism, religious faith need not include belief, but only some cognitively weaker attitude. This view comes with great promises, as it offers a way for the agnostic to partake in religion. My concern is how such a non-doxastic faith might be understood as a rational attitude. I offer three desiderata for any account of rational, non-doxas

As the use of engineered nanomaterials increases, so does the risk of them spreading to natural ecosystems. Hitherto, knowledge regarding the toxic properties of nanoparticles (NP’s) and their potential interactions with natural bio-organic molecules adsorbed to them, and thereby forming surface coronas, is limited. However, we show here that the toxic effect of NPs of tungsten carbide cobalt (WC–

Background: Being an informal carer of a person with dementia (PwD) can have a negative effect on the carer’s health and quality of life, and spouse carers have been found to be especially vulnerable. Yet relatively little is known about the care provided and support received by spouse carers. This study compares spouse carers to other informal carers of PwDs regarding their care provision, the su

The numerical simulation of the induction heating process can be computationally expensive, especially if ferromagnetic materials are studied. There are several analytical models that describe the electromagnetic phenomena. However, these are very limited by the geometry of the coil and the workpiece. Thus, the usual method for computing more complex systems is to use the finite element method to

Background: The aim of this study was to analyze overall survival in endometrial cancer patients’ FIGO stages I-III in relation to surgical approach; minimally invasive (MIS) or open surgery (laparotomy). Methods: A population-based retrospective study of 7275 endometrial cancer patients included in the Swedish Quality Registry for Gynecologic Cancer diagnosed from 2010 to 2018. Cox proportional h

Background: Mast cells (MCs) are known to contribute to both acute and chronic inflammation. Bronchial epithelial cells are the first line of defence against pathogens and a deficient anti-viral response has been suggested to play a role in the pathogenesis of asthma exacerbations. However, effects of MC mediators on bronchial epithelial immune response have been less studied. The aim of this stud