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YKL-40, a mammalian member of the chitinase family, is a matrix protein of specific granules in human neutrophils

YKL-40, also called human cartilage glycoprotein-39 (HC gp-39), is a member of family 18 glycosyl hydrolases. YKL-40 is secreted by chondrocytes, synovial cells, and macrophages, and recently it has been reported that YKL-40 has a role as an autoantigen in rheumatoid arthritis (RA). The function of YKL-40 is unknown, but the pattern of its expression in normal and disease states suggests that it c

Patient outcomes following GPs’ educations about COPD : a cluster randomized controlled trial

This study aimed to compare patient outcomes following case method learning and traditional lectures as methods for continuing medical education (CME) about chronic obstructive pulmonary disease (COPD) for general practitioners (GPs) in Sweden. In a pragmatic cluster randomized controlled trial, COPD patients (n = 425; case method group n = 209, traditional lectures group n = 216) from 24 primary

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In this article we review the legal regulation of an obligation to self-isolate in Ukraine. For the period from 22 April 2020 till 22 June 2020 four groups of persons were obliged to self-isolate due to COVID-19. These groups are: persons diagnosed with or suspected to have COVID-19, persons that have been in contact with those diagnosed with COVID-19, those who consented to self-isolation when en

Multimethod characterization of a chlorinated solvents contaminated site and geoelectrical monitoring of in-situ bioremediation

Soil contamination is a widespread problem and actions need to be taken in order toprevent damage to the groundwater and the life around the contaminated sites. InSweden more than 80.000 sites are potentially contaminated, therefore there is ademand for accurate and efficient methods for site characterization and soilremediation. In the past, the preferred methodology for soil remediation involved

Failure of responsive regulation? : Pharmaceutical marketing, corporate impression management and off-label promotion of enzalutamide in Europe

“Responsive regulation” has been proposed to offset pharmaceutical industry illicit behaviour in areas such as drug marketing based on self- regulation backed up with threats of government sanctions. We explore the efficacy of responsive regulation by tracing recent investigations by the UK pharmaceutical industry self-regulatory authority into the firm Astellas’s illicit promotion of a top-sellin

The importance of biomechanical restoration for total hip arthroplasty

Höftprotesoperationer har blivit ett säkert och mycket framgångsrikt kirurgiskt ingrepp och lever upp till mycket av de förväntningar som patienterna har. Förbättring av material, protesdesign och kirurgiska tekniker har förlängt protesöverlevnaden påtagligt. Emellertid är icke optimal protesplacering och felaktigt val av komponentstorlekar känt för att öka risken för biomekaniska problem och ökatTotal hip arthroplasty (THA) has become a safe and very successful surgical intervention. A vast majority of patients get their expectations met. Improvement of materials, implant designs, and surgical techniques, have extended prosthetic survival. However, inferior placement and sizing of a hip prosthesis are known to increase the risk of mechanical failure, wear, and early loosening as well as p

Situerad flerspråkighet : Exemplet Caroline Bergvalls Drift

Den flerspråkiga texten bör studeras och förstås som en situerad händelse. Det är utgångspunkten i denna artikel, som med Caroline Bergvall och hennes ensembles framförande av Drift i norra Italien i september 2018 – och hennes bok med samma namn från 2014 – som exempel undersöker hur och ifall Roman Jakobsons kommunikationsmodell från 1958 kan bidra till en djupare förståelse av verket. Genom att

Plågsamt aktuell läsning

Recension av nyöversättningen av Harper Lees To kill a mockingbird.Title in web version: Harper Lees ”Att döda en härmtrast” är plågsamt aktuellReviewed work: Att döda en härmtrast / Harper Lee, ISBN 9789100168186.

Multinational companies’ roles in start-up incubation ecosystems: The case of Microsoft Innovation Centers in Brazil

This chapter analyses the roles and activities of multinational companies (MNCs) in an entrepreneurial ecosystem (EE) and local start-up incubation. Drawing from literature regarding EEs and incubation policy, we present an example of a type of intervention under-theorized to date: incubation efforts stemming from MNCs rather than government or universities. Presenting the case of Microsoft Innova

Variation in microbial biomass and community composition based on long-term fertilization regimes in paddy soil profiles

Fertilization is a common approach to increase or sustain soil fertility, but its impact on microbial biomass and community structure remains controversial, particularly in paddy soils. In this study, we investigated the effect of different long-term fertilization strategies, beginning in 1986, namely no fertilization, mineral fertilization, mineral fertilization combined with rice straw or chicke