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CD163+ macrophages are associated with a vulnerable plaque phenotype in human carotid plaques

Macrophages are a functionally heterogeneous group of immune cells abundant in atherosclerotic plaques. Macrophages expressing CD163 are associated with intraplaque hemorrhage and have previously been considered atheroprotective. However, in a recent study CD163-deficient atherosclerotic ApoE−/− mice exhibited smaller and less complex plaques, suggesting a proatherogenic role of CD163. Previous sm

Prognosis of Syncope With Head Injury : a Tertiary Center Perspective

Aim: Head injury is the most common trauma occurring in syncope. We aimed to assess whether syncope as cause of head-trauma affects short-and long-term prognosis. Methods: From a database retrospective analysis of 97,014 individuals attending Emergency Department (ED), we selected data of patients with traumatic head injury including age, gender, injury mechanism, brain imaging, multiple traumas,

Safety and health effects in high and ultra-high field MR

Background: More than 70 million magnetic resonance (MR) examinations are produced every year. Patients and personnel are exposed to electromagnetic fields at levels that exceed those normally found in our surroundings or in industry. Three types of electromagnetic field exposure must be considered in regard to MR safety: the strong force of the static magnetic field, the time-varying gradient mag

The American Inventors Protection Act : A Natural Experiment on Innovation Disclosure and the Cost of Debt

We examine the impact of innovation disclosure through patenting on firms' cost of debt, focusing on the American Inventors Protection Act (AIPA) as an exogenous shock in innovation disclosure regulation. Post-AIPA, firms have an incentive to apply for patents only if commercial success is likely. Accordingly, we expect post-AIPA patents to be a better proxy for successful innovation activity, and

Computational Atomic Structure: Applications to Astrophysics and Nuclear Structure

This thesis deals with the modelling of atoms and ions. In heavy systems, where the effect of the nuclear size must be considered, a fully relativistic treatment based on the Dirac-Coulomb Hamiltonian is needed. Chapter two of the thesis provides an introduction to the basic principles of the fully relativistic multiconfiguration Dirac-Hartree-Fock (MCDHF) method, which is a variational approach f

Analysis of the environmental impacts of 218 consumption items : Greenhouse gas emissions, land use and water use per SEK and kg.

A software application combining process and input–output analysis (EAP) was used toanalyze 218 consumer products and services for environmental impacts over their lifecycle. The results are available as carbon dioxide equivalents, land use and water use perkg and per SEK. The products and services were chosen either because they are consumedby many Swedish consumers today or because they may be c