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Principal Component Analyses (PCA)-based findings in population genetic studies are highly biased and must be reevaluated

Principal Component Analysis (PCA) is a multivariate analysis that reduces the complexity of datasets while preserving data covariance. The outcome can be visualized on colorful scatterplots, ideally with only a minimal loss of information. PCA applications, implemented in well-cited packages like EIGENSOFT and PLINK, are extensively used as the foremost analyses in population genetics and related

Temporal population structure, a genetic dating method for ancient Eurasian genomes from the past 10,000 years

Radiocarbon dating is the gold standard in archeology to estimate the age of skeletons, a key to studying their origins. Many published ancient genomes lack reliable and direct dates, which results in obscure and contradictory reports. We developed the temporal population structure (TPS), a DNA-based dating method for genomes ranging from the Late Mesolithic to today, and applied it to 3,591 ancie

Transnational England : Home and Abroad, 1780-1860

The rise of the modern English nation coincided with England’s increased encounters with other peoples, both at home and abroad. Their cultures and ideas—artistic, religious, political, and philosophical—contributed, in turn, to the composition of England’s own domestic identity. Transnational England sheds light on this exchange through a close investigation of the literatures of the time, from d

A Retrospective Study on Clinical Assessment of Cognitive Impairment in a Swedish Cohort : Is There Inequality Between Natives and Foreign-Born?

BACKGROUND: People with a migration background are underrepresented in dementia research and disfavored in assessment and treatment, and many foreign-born individuals with dementia remain undiagnosed.OBJECTIVE: The aim of this study was to examine whether there is inequality in the clinical assessment of dementia between native and foreign-born individuals in Sweden.METHODS: Information was gather