Sökresultat

Filtyp

Din sökning på "*" gav 531332 sökträffar

Mobilizing the Rights of Migrant Workers: Swedish Trade Unions’ Engagement with Law and the Courts

Migrant workers, both regular and irregular, are at particular risk of having their rights violated. At the same time, there has been an absence of support for exploited immigrant workers from Swedish authorities and civil society. Lately, a number of trade unions and semi-union organisations in Sweden have developed methods to mobilize the rights of migrant workers experiencing exploitation on th

Exploring Spatial Heterogeneity of Immune Cells in Nasopharyngeal Cancer

Nasopharyngeal cancer (NPC) is a malignant tumor. In a recent publication, we described the presence and distribution of CD8+ T cells in NPC and used the information to identify ‘inflamed’, ‘immune-excluded’, and ‘desert’ immune phenotypes, where ‘inflamed’ and ‘immune-excluded’ NPCs were correlated with CD8 T cell infiltration and survival. Arguably, more detailed and, in particular, spatially re

Effects of mutant huntingtin in oxytocin neurons on non-motor features of Huntington's disease

Background: Early non-motor features including anxiety, depression and altered social cognition are present in Huntington's disease (HD). The underlying neurobiological mechanisms are not known. Oxytocin (OXT) is involved in the regulation of emotion, social cognition and metabolism, and our previous work showed that the OXT system is affected early in HD. The aim of the study was to investigate t

The most important theoretical developments leading to the current understanding of heavy-element stability : With some personal recollections from the past 55 years (1965–2020)

We discuss the sequence of developments that over the past 90 years led to current insights on heavy-element stability. The semi-empirical mass model, and its extension to deformed shapes, developed in the period 1936–1950 allowed the interpretation of nuclear fission. Around 1950 the spherical single-particle model was developed, soon after with extension to deformed nuclei. Speculations about a

Driving sustainability in emerging markets: The leading role of multinationals.

This paper focuses on the different activities that multinational enterprises (MNEs) can develop to promote sustainability through a market-driving process that shapes market conditions and influences critical stakeholders. Our focus is on interactions with external and internal stakeholders that drive sustainability. Empirically, this study is based on qualitative case studies of two Swedish MNEs

Plasma proteomic changes in response to exercise training are associated with cardiorespiratory fitness adaptations

Regular exercise leads to widespread salutary effects, and there is increasing recognition that exercise-stimulated circulating proteins can impart health benefits. Despite this, limited data exist regarding the plasma proteomic changes that occur in response to regular exercise. Here, we perform large-scale plasma proteomic profiling in 654 healthy human study participants before and after a supe

Creating a Sustainable Competitive Position Through Ethical Behaviour

In this chapter, we discuss the main themes of the book and give examples of how the rest of the chapters are related to these themes. We have identified two main aspects that are partly overlapping and are equally relevant for international firms’ work with ethical questions related to their business. One concerns how ethical behaviour related to sustainability can be applied as a main part of fi

Towards a Global Sustainability Approach: Challenges and Opportunities for Multinationals.

We discuss how multinational enterprises (MNEs) can play a leading role and take more responsibility towards reducing inequalities by developing a global sustainability regime. We especially focus on how this may contribute towards the United Nations’ Sustainable Development Goals (UN SDGs). Our purpose is to identify and discuss the components and activities that are needed to develop such a stra

When Institutional Logics Collide: How International Firms Navigate Sustainability Values in Global Markets

This book chapter takes an institutional perspective on competing logics in global markets concerned with sustainability values and how market actors in the form of buyers and sellers attempt to solve these conflicting situations. We do this by identifying competing institutional logics in global market contexts aiming for sustainability values, together with techniques for navigating these compet

Accounting for long-term motivation and sustained motivated learning : Motivational currents, self-concordant vision, and persistence in language learning

Although temporal conceptualizations of motivational processes have not held center stage in motivation science, the situation is currently changing. Drawing on work in the subfield of language learning motivation, where the motivational endurance needed to master a second language has been a major concern, the aim of this article is to contribute to the body of work currently exploring motivation

Applying Unique Molecular Indices with an Extensive All-in-One Forensic SNP Panel for Improved Genotype Accuracy and Sensitivity

One of the major challenges in forensic genetics is being able to detect very small amounts of DNA. Massively parallel sequencing (MPS) enables sensitive detection; however, genotype errors may exist and could interfere with the interpretation. Common errors in MPS-based analysis are often induced during PCR or sequencing. Unique molecular indices (UMIs) are short random nucleotide sequences ligat

Creating a Sustainable Competitive Position: Ethical Challenges for International Firms

The importance of ethical practices and a sustainable competitive position is being increasingly emphasised by all types of business and across all industries. The chapters collected in Creating a Sustainable Competitive Position discuss how international firms work with sustainable strategies and their relationship with the society and environment while exploring the different opportunities and c

Morphology-Dependent Interactions between α-Synuclein Monomers and Fibrils

Amyloid fibrils may adopt different morphologies depending on the solution conditions and the protein sequence. Here, we show that two chemically identical but morphologically distinct α-synuclein fibrils can form under identical conditions. This was observed by nuclear magnetic resonance (NMR), circular dichroism (CD), and fluorescence spectroscopy, as well as by cryo-transmission electron micros

Genetic evidence implicating natriuretic peptide receptor-3 in cardiovascular disease risk : a Mendelian randomization study

Background: C-type natriuretic peptide (CNP) is a known target for promoting growth and has been implicated as a therapeutic opportunity for the prevention and treatment of cardiovascular disease (CVD). This study aimed to explore the effect of CNP on CVD risk using the Mendelian randomization (MR) framework. Methods: Instrumental variables mimicking the effects of pharmacological intervention on

Modelling natural pest control across the world’s agroecosystems – an archetype approach

Control of crop pests by shifting host plant availability and natural enemy activity at landscape scales has great potential to enhance the sustainability of agriculture. However, mainstreaming natural pest control requires improved understanding of how its benefits can be realized across a variety of agroecologies. Empirical studies suggest significant but highly variable responses of natural pes

No title

I Norge ble en ny modell for beregning av nettleie innført 1. juli 2022. Formålet med den nye nettleien er å motivere husholdninger til å fordele strømforbruket jevnere utover døgnet. På tidspunktet hvor den nye nettleien ble planlagt innført var det liten kunnskap om virkninger av slike virkemidler på forbrukere. Flexeffect-prosjektet startet har undersøkt virkninger virkemidler for fleksibel st

Biofilm formation on endovascular aneurysm repair (EVAR) grafts– a proof of concept in vitro model

ObjectivesAn endovascular aneurysm repair (EVAR) graft is a catheter-implanted vascular prosthesis and is the preferred treatment for patients with aortic aneurysm. If an EVAR graft becomes the focus of infection, the treatment possibilities are limited as it is technically difficult to remove the graft to obtain source control. This study examines whether Pseudomonas aeruginosa and Staphylococcus

The Digitalisation of Swedish Housing : The First Forty Years

So called ‘smart’ built environments operate in a peculiar temporal nexus: they are simultaneously just around the corner, already here, and yesterday’s news. This is usually put down to hype and hyperbole, but it may well be argued that smart built environments do indeed exist across temporal dimensions – only not in the way we imagine them to.Instead of speaking of a digital turn in housing, we

Towards an accurate method for column void volume determination using liquid chromatography-mass spectrometry

Prediction of analyte retention times requires prior knowledge of the column void volume, the measurement of which is still highly contested within the literature and therefore experimental based prediction is often used. In this study, we investigated deuterated acetonitrile as an isotopically labelled mobile phase component to observe its elution behaviour in a binary mixture with water at 25 di

An exploration into the use of Hansen solubility parameters for modelling reversed-phase chromatographic separations

The suitability of Hansen solubility parameters as descriptors for modelling analyte retention during reversed-phase chromatographic experiments was investigated. A novel theoretical model using Hansen solubility parameters as the basis for a complete mathematical derivation of the model was developed. The theoretical model also includes the cavitation volumes of the analytes, which were calculate