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The addition of S100B to guidelines for management of mild head injury is potentially cost saving

Background: Mild traumatic brain injury (TBI) is associated with substantial costs due to over-triage of patients to computed tomography (CT) scanning, despite validated decision rules. Serum biomarker S100B has shown promise for safely omitting CT scans but the economic impact from clinical use has never been reported. In 2007, S100B was adapted into the existing Scandinavian management guideline

Porous silicon microarray for simultaneous fluorometric immunoassay of the biomarkers prostate-specific antigen and human glandular kallikrein 2

The authors have developed a porous silicon (P-Si) based duplex antibody microarray platform for simultaneous quantitation of the biomarkers prostate-specific antigen (PSA) and human glandular kallikrein 2 (hK2) in serum. Pore size-controlled P-Si surfaces have an extremely enlarged surface area that enables high-density immobilization of fluorescently labeled antibodies by physical adsorption. Au

Late Holocene landscape development around a Roman Iron Age mass grave, Alken Enge, Denmark

Sediments from the small lake Ilsø situated in the Illerup/Alken Enge Valley were studied in order to investigate past landscape development at the time of a probably ritual human mass burial following battle during the Roman Iron Age (ad 1–400). A pollen record from Ilsø and a number of other records from Jutland were combined using the Landscape Reconstruction Algorithm to reconstruct local vege

Exploring the Loading Capacity of Generation Six to Eight Dendronized Polymers in Aqueous Solution

Aspects of size, structural (im)perfection, inner density, and guest molecule loading capacity of dendronized polymers (DPs) of high generation (6≤g≤8) in aqueous solution are studied using electron paramagnetic resonance spectroscopy on amphiphilic, spin-labeled guest molecules. The results show that the interior of the charged DPs is strongly polar, especially in comparison to their lower genera

Individual and environmental factors underlying life space of older people - study protocol and design of a cohort study on life-space mobility in old age (LISPE)

Background A crucial issue for the sustainability of societies is how to maintain health and functioning in older people. With increasing age, losses in vision, hearing, balance, mobility and cognitive capacity render older people particularly exposed to environmental barriers. A central building block of human functioning is walking. Walking ifficulties may start to develop in midlife and become

Retinal S-antigen: immunocytochemical and immunochemical studies on distribution in animal photoreceptors and pineal organs

Antiserum against bovine retinal S-antigen, a soluble protein (MW = 50 kDa) thought to be involved in phototransduction, was used in an immunohistochemical and immunochemical study of vertebrate eyes and pineal systems and invertebrate photoreceptor organs. Positive reactions, not seen with antiserum preabsorbed with highly purified S-antigen, were observed in planarian and starfish ocelli; scallo

A Tale of Beauties and Beasts: Testing the Optimal Disclosure Hypothesis

According to the cost-of-capital hypothesis, increased voluntary disclosure should reduce information asymmetries, lower the cost of capital, and increase firm value. The optimal-disclosure hypothesis, however, predicts that costs related to voluntary disclosure lead to the existence of an interior optimum of disclosure that maximizes firm value. These hypotheses are empirically tested using a pre

Laser-induced phosphorescence spectroscopy: development and application of thermographic phosphors (TP) for thermometry in combustion environments

In this chapter a temperature probing technique based on the spectroscopy of inorganic luminescent materials is described and exemplified in experiments related to combustion. The basic features of thermographic phosphors which enable remote temperature diagnostics to be performed with a high degree of sensitivity and accuracy, are outlined. This technique is superior to those based on thermocoupl

Likelihood Ratio Tests for a Unit Root in Panels with Random Effects

Because of the fixed heterogeneity of their models, most panel unit root tests impose restrictions on the rate at which the number of time periods, T, and the number of cross-section units, N, go to infinity. A common example of such a restriction isN/T→0, which in practice means that T≫N, a condition that is not always met. In the current paper the heterogeneity is given a parsimonious random eff

Numerical study of natural convection for Al2O3 and CuO nanofluids inside different enclosures

In this study steady-state natural convection for Al2O3 and CuO nanofluids inside different enclosures are numerically investigated. Natural convection is concerned due to a temperature difference between hot and cold surfaces. Rectangular and curved enclosures are investigated. The Boussinesq approximation is used to form the governing equations and the commercial software package ANSYS Fluent ve

Aggregation behavior of aqueous cellulose nanocrystals : the effect of inorganic salts

Natural anisotropic building-blocks such as cellulose nanocrystals (CNCs) have attracted considerable attention due to their biodegradability and nanometer-size. In this work the colloidal behavior of CNCs, obtained from sulfuric acid hydrolysis of microcrystalline cellulose, has been studied in presence of salts of different valences. The influence on the colloidal stability and nature of aggrega

Smartphone Positioning in Multi-Floor Environments Without Calibration or Added Infrastructure

Indoor positioning for smartphone usershas received a lot of attention in recent years. Whilemany solutions have been developed, most rely on aneed for pre-deployment of infrastructure or collectingground truth data to train on. In this paper we see whatcan be done using existing WiFi-infrastructure andReceived Signal Strength from these to smartphones,not using any calibration of the signal envir

Science and proven experience : a Swedish variety of evidence-based medicine?

A key question for evidence-based medicine (EBM) is how best to model the way in which EBM should “[integrate] individual clinical expertise and the best external evidence” (Sackett et al. 1996). We argue that the formulations and models available in the literature today are modest variations on a common theme and face very similar problems. For example, both the early and updated models of evidenA key question for evidence-based medicine (EBM) is how best to model the way in which EBM should “[integrate] individual clinical expertise and the best external evidence” (Sackett et al. 1996). We argue that the formulations and models available in the literature today are modest variations on a common theme and face very similar problems. For example, both the early and updated models of eviden

Protein-dependent membrane interaction of a partially disordered protein complex with oleic acid : Implications for cancer lipidomics

Bovine α-lactalbumin (BLA) forms cytotoxic complexes with oleic acid (OA) that perturbs tumor cell membranes, but molecular determinants of these membrane-interactions remain poorly understood. Here, we aim to obtain molecular insights into the interaction of BLA/BLA-OA complex with model membranes. We characterized the folding state of BLA-OA complex using tryptophan fluorescence and resolved res

Assessment of diesel-contaminated domestic wastewater treated by constructed wetlands for irrigation of chillies grown in a greenhouse

In order to avoid environmental pollution and eliminate the need for using fertiliser, this study assessed for the first time the optimum performance of mature (in operation since 2011) vertical flow constructed wetlands in treating domestic wastewater (with and without hydrocarbon) and the subsequent recycling of the outflow to irrigate chillies (De Cayenne; Capsicum annuum (Linnaeus) Longum Grou

Betonguttorkning med byggcement

I denna artikel redogörs för uttorkning hos betong med Byggcement jämfört med andra cementsorter: Slite Std-cement samt anläggningscement. Inverkan av silikastoft på uttorkningen hos Slite Std-cement redovisas. För ändamålet studerades 14 betonger upp till ett halvt år. Inverkan av självuttorkning, lufthärdning och vattenlagring fanns med i programmet. Resultaten visar att uttorkningen i huvudsak