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The complement system plays a pivotal protective role in the innate immune response to many pathogens including flaviviruses. Flavivirus nonstructural protein 1 (NS1) is a secreted nonstructural glycoprotein that accumulates in plasma to high levels and is displayed on the surface of infected cells but absent from viral particles. Previous work has defined an immune evasion role of flavivirus NS1

Pt-TiO2-C composites with different titanium oxide loading were synthesized by photo-deposition and chemical vapor deposition methods. The changes in their electronic properties improve the electrochemical activity toward the oxygen reduction reaction (ORR) compared to the Pt-C catalyst synthesized at the same conditions. The platinum samples were physically characterized by means of Transmission

This thesis aimed to investigate possibilities to utilize death certificates in cancer epidemiology by analyzing nationwide databases from Sweden. Excessive information is available when investigating causes of death in cancer patients, including comorbidities and metastatic patterns. We used the Swedish Family- Cancer Database, which includes data from e.g. the Cause of Death Register and the Can

We report a genome-wide association study for melanoma that was conducted by the GenoMEL Consortium. Our discovery phase included 2,981 individuals with melanoma and 1,982 study-specific control individuals of European ancestry, as well as an additional 6,426 control subjects from French or British populations, all of whom were genotyped for 317,000 or 610,000 single-nucleotide polymorphisms (SNPs

Skeletal muscle is a dynamic tissue with a remarkable ability to continuously respond to environmental stimuli. Among its adaptive responses is the widely investigated ability of skeletal muscle to regenerate after loading or injury or both. Although significant basic science efforts have been dedicated to better understand the underlying mechanism controlling skeletal muscle regeneration, there h

The collective wobbling mode, the strongest signature for the rotation of a triaxial nucleus, has previously been seen only in a few Lu isotopes in spite of extensive searches in nearby isotopes. A sequence of transitions in the N = 94 Ta-167 nucleus exhibiting features similar to those attributed to the wobbling bands in the Lu nuclei has now been found. This band feeds into the pi i(13/2) band a

The proportion of hand injuries in Swedish children is the second highest in relation to other parts of the body. The incidence of hand injuries in these children has not yet been estimated. In addition, aetiologies, injury patterns and costs among Swedish children have not been presented on a regional or national level. Also, very few studies have focused on hand injuries within specific ages for

Recent studies on young men from the general population have demonstrated geographic and ethnic differences in semen quality. The aim of this study was to investigate whether reported ethnic differences in semen quality might be associated with the maternally derived CAG and GGN polymorphisms in the androgen receptor gene or paternal ethnicity. In total 114 military conscripts from Latvia were inc

Popular Abstract in Swedish Biologiska organismer har en fantastisk förmåga att anpassa sig till alla möjliga miljöer. Människans aktiviteter på jorden har skapat många nya habitat för olika typer av organismer; t ex kan vissa organismer växa på sten och vertikala klippor och när människor bygger hus så kan dessa organismer flytta över till väggar och tak som blir nya biotoper att leva på. Några aBiological organisms have an incredible ability to adapt to almost any environment and the humans activities on earth have created many new habitats for different kinds of organisms. For example can certain organisms grow on rocks and vertical cliffs, and when humans started building houses with mineral based façades, some organisms found that these were new habitats to live on. Some of these expa

A measurement of event shape variables is presented for large momentum transfer proton-proton collisions using the ATLAS detector at the Large Hadron Collider. Six event shape variables calculated using hadronic jets are studied in inclusive multi-jet events in 35 pb(-1) of integrated luminosity at a center-of-mass energy of root s = 7 TeV. These measurements are compared to predictions by three M

The HIV-1 epidemic in West Africa has been dominated by subtype A and the recombinant form CRF02_AG. Little is known about the origins and the evolutionary history of HIV-1 in this region. We employed Maximum likelihood and Bayesian methods in combination with temporal and spatial information to reconstruct the HIV-1 subtype distribution, demographic history and migration patterns over time in Gui

A search for new interactions and resonances produced in LHC proton-proton (pp) collisions at a centre-of-mass energy root s = 7 TeV was performed with the ATLAS detector. Using a dataset with an integrated luminosity of 36 pb(-1), dijet mass and angular distributions were measured up to dijet masses of similar to 3.5 TeV and were found to be in good agreement with Standard Model predictions. This

Giant bamboo plantations are currently being established in the Southern Africa region and can be considered as potential lignocellulosic feedstock for the production of second generation bioethanol. In this study, giant bamboo internodal material was subjected to sulphur dioxide (SO2) impregnated steam pretreatment prior to enzymatic hydrolysis. The effect of temperature, residence time, and acid

The aim of this single-case study was to describe the staff's collaborative work process for a period of 3.5 years caring for an adolescent boy with autism and intellectual disabilities living in an apartment of his own together with his caregivers. The longitudinal data included the staff's (two men and two women) common open diary, repeated individual interviews and focus group interviews. Detai

Hyaluronan is an unsulfated linear glycosaminoglycan with the ability to nucleate extracellular matrices by the formation of aggregates with lecticans. These matrices are essential during development of the central nervous system. In the prospective white matter of the developing brain hyaluronan is organized into fiber-like structures according to confocal microscopy of fixed slices which may gui

III-V semiconductors have attractive transport properties suitable for low-power, high-speed complementary metal oxide-semiconductor (CMOS) implementation, but major challenges related to cointegration of III-V n- and p-type metal-oxide-semiconductor field-effect transistors (MOSFETs) on low-cost Si substrates have so far hindered their use for large scale logic circuits. By using a novel approach