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The Atiyah--Singer index theorem is a foundational result in mathematics, providing a deep connection between the analytical properties of an elliptic differential operator and the topological properties of its underlying manifold. This thesis focuses on a numerical approach to index theory for generalized Toeplitz operators. Building on the work of Loring and Schulz-Baldes, we utilize the spectra
An exploration of perspectives in art through technology, by way of Graham Harman
Background: Trichotillomania is an understudied psychiatric disorder characterized by repeated hair-pulling resulting in hair loss. Little is known about the risk of problematic substance use in this patient group. In this nationwide matched cohort study, we investigated the association between trichotillomania and substance-related problems. Methods: We linked various nationwide administrative an
The one-particle Green function of a many-electron system is traditionally formulated within the self-energy picture. A different formalism was recently proposed, in which the self-energy is replaced by a dynamical exchange-correlation field, which acts on the Green function locally in both space and time. It was found that there exists a fundamental quantity, referred to as the dynamical exchange
Denna avhandling utforskar möjligheter och utmaningar för bildandet av transnationell feministisk solidaritet i Mellanöstern, med fokus på Egypten och Tunisien. Avhandlingen fokuserar på feministiska organisationers arbete med att bygga transnationella allianser och stödnätverk. Mer konkret utforskas hur detta arbete balanseras med önskan om att förbli förankrade på lokal nivå och centrera lokala This dissertation explores possibilities and challenges to the formation of transnational feminist solidarity in the Middle Eastern context, focusing on Egypt and Tunisia. In particular, it asks how feminist organisations balance the work towards building transnational alliances and support networks with the imperative to remain grounded at the local level and centre local communities in their wor
Air pollution is increasingly discussed as a risk factor for dementia, but the biological mechanisms are not yet fully understood. Biological markers like telomere length are relevant to study with air pollution, as they are associated with aging and dementia. The study aimed to investigate the relationship between source-specific air pollution exposure and telomere length in a low-level air pollu
Background: Amyotrophic lateral sclerosis (ALS) is invariably fatal but there are large variations in the rate of progression. The lack of predictability can make it difficult to plan clinical interventions. This includes the requirement for gastrostomy where early or late placement can adversely impact quality of life and survival. Methods: We designed a model to predict the timing of gastrostomy
Stroke and anemia are both prevalent conditions with significant health burdens, yet their bidirectional relationship remains poorly understood. Anemia affects up to 29 % of stroke patients and is associated with increased worse outcomes. However, the causal nature of this association, particularly concerning different anemia subtypes, remains controversial, and there is a lack of clear targets an
Previous studies identified atrophy-based Alzheimer's disease(AD) subtypes linked to distinct clinical symptoms, but their consistency across subtyping approaches remains unclear. This large-scale study evaluates subtype concordance using two data-driven approaches. In this work, we analyzed data from n=10,011 patients across 10 AD cohorts spanning Europe, the US, and Australia, extracting regiona
Background: Fiducial markers in image-guided prostate cancer radiotherapy reduce geometric uncertainty during daily patient setup and enable assessment of target position changes. Diffusion-weighted magnetic resonance imaging (MRI) for target delineation improves prostate cancer localization, beneficial for intraprostatic focal boost. Artifacts from fiducial markers on prostate diffusion-weighted
