The Swedish national guidelines for treatment of acute myeloid leukemia (AML) recommend analysis of measurable residual disease (MRD) by multiparameter flow cytometry (MFC) in bone marrow in the routine clinical setting. The Swedish AML registry contains such MRD data in AML patients diagnosed 2011-2019. Of 327 patients with AML (non-APL) with MRD-results reported in complete remission after two c

It is composed following the Common European Framework of Reference for Languages (A1-B2 levels, understanding of oral and written texts). It turns to good account the composition exercises of Norwegian, Czech, Swedish and Arab students of the previous ten years teaching experience; it promotes Romanian culture and civilization landmarks; it considers probable day-to-day language understanding sit

Most of the drugs currently prescribed for cancer treatment are riddled with substantial side effects. In order to develop more effective and specific strategies to treat cancer, it is of importance to understand the biology of drug targets, particularly the newly emerging ones. A comprehensive evaluation of these targets will benefit drug development with increased likelihood for success in clini

We present results from neutron-imaging studies of slow, vacuum pyrolysis of beech, poplar and conifer wood, and pelletized biomass from room temperature up to 1000 °C. A detailed and quantitative method to extract 2D (in situ neutron radiography, NR) and 3D (ex situ neutron computed tomography, NCT) information on structural transformation and elemental hydrogen content has been developed. NCT an

Surrogate measures of safety (SMoS) can enable quick, pro-active, and detailed safety evaluations by studying near-crashes. A critical concern regarding SMoS is their validity. This study focused on the validity of two commonly used SMoS indicators—minimum time to collision and post-encroachment time—with a specific focus on bicyclist–motor vehicle interactions. The study was divided into two main

The ‘planetary boundaries’ framework identifies Earth system processes that contribute to the stability and resilience of the planet (Rockström et al., 2009a), setting out the limits to changes the Earth can support for remaining in a Holocene-like state. A key question for global sustainable development that emerges from this framework is how to secure social equity while respecting planetary bou

Recent literature has recognised the value of food sovereignty and human rights frameworks in agrarian struggles. Relatively little attention has gone toward how agrarian movements develop and apply their own rights discourses to further demands for social justice. This study considers Brazil's landless movement (MST) between 1984 and 1995, revealing three distinct rights discourses that recruited

Pebbles of millimeter sizes are abundant in protoplanetary discs around young stars. Chondrules inside primitive meteorites - formed by melting of dust aggregate pebbles or in impacts between planetesimals - have similar sizes. The role of pebble accretion for terrestrial planet formation is nevertheless unclear. Here, we present a model where inward-drifting pebbles feed the growth of terrestrial

Background: Concurrent chemoradiotherapy is standard treatment for limited stage small-cell lung cancer (SCLC). Twice-daily thoracic radiotherapy of 45 Gy in 30 fractions is considered to be the most effective schedule. The aim of this study was to investigate whether high-dose, twice-daily thoracic radiotherapy of 60 Gy in 40 fractions improves survival. Methods: This open-label, randomised, phas

In vehicular communications systems the channel estimation filter suppresses the additive noise in channel estimates obtained from pilot symbols. Vehicular channels show local stationarity for a finite region in time and frequency, only. Such a process can be divided into consecutive stationarity regions, allowing to calculate a Wiener filter. We analyze the increase of the mean square error (MSE)

Tungsten (W) and niobium (Nb) belong to the refractory metal group and are used as alloying elements in steels and superalloys for high demand products. These metals are also used in a high purity single-phase state for products within nuclear, space, military and research facilities.In the current study, tool wear development and surface quality at different cutting conditions have been evaluated

Recension av Poitr Wawrzeniuk, Med polska ögon: försvarsförmåga och hotbilder kring Östersjön i polsk militärrapportering 1919-1939

In recent years, nonhuman ancient DNA studies have begun to focus on larger sample sizes and whole genomes, offering the potential to reveal exciting and hitherto unknown answers to ongoing biological and archaeological questions. However, one major limitation to such studies is the substantial financial and time investments still required during sample screening, due to uncertainty regarding succ

Background: Early detection of renal cell carcinoma (RCC) has the potential to improve disease outcomes. No screening program for sporadic RCC is in place. Given relatively low incidence, screening would need to focus on people at high risk of clinically meaningful disease so as to limit overdiagnosis and screen-detected false positives. Methods: Among 192,172 participants from the European Prospe

We report here the complete genome sequence and characterization of Yersinia bacteriophage vB_YenP_ϕ80-18. ϕ80-18 was isolated in 1991 using a Y. enterocolitica serotype O:8 strain 8081 as a host from a sewage sample in Turku, Finland, and based on its morphological and genomic features is classified as a podovirus. The genome is 42 kb in size and has 325 bp direct terminal repeats characteristic