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Minimal clinically important differences for Dyspnea-12 and MDP scores are similar at 2 weeks and 6 months : follow-up of a longitudinal clinical study

Chronic breathlessness is a dominating symptom that restricts daily life for many people with cardiorespiratory disease [1]. Different dimensions of the symptom, such as the intensity, sensory qualities and emotional responses, can be assessed using the instruments Dyspnea-12 (D-12) [2] and the Multidimensional Dyspnea Profile (MDP) [3], which share similarities in the underlying constructs of wha

Xylooligosaccharides Increase Bifidobacteria and Lachnospiraceae in Mice on a High-Fat Diet, with a Concomitant Increase in Short-Chain Fatty Acids, Especially Butyric Acid

Effects of xylooligosaccharides (XOSs) as well as a mixture of XOS, inulin, oligofructose, and partially hydrolyzed guar gum (MIX) in mice fed a high-fat diet (HFD) were studied. Control groups were fed an HFD or a low-fat diet. Special attention was paid to the cecal composition of the gut microbiota and formation of short-chain fatty acids, but metabolic parameters were also documented. The XOS

Blodkomponenter och helblod – så framställs och används de

Krav på innehåll i blodkomponenter, virustest och kvalitetskriterier regleras i ett EU-direktiv och i Socialstyrelsens föreskrifter. Blodtransfusioner är en vanlig och viktig medicinsk behandling.Det saknas nationella riktlinjer för transfusionsindikationer och uppföljning av blodtransfusioner i Sverige.Det finns medicinsk evidens för en generellt restriktiv transfusionsstrategi.Vid stora blödningSweden does not have a national blood authority and guidelines for blood transfusions are lacking, leading to varying routines of production and usage of blood in the different regions. The minimum quality requirements are defined in EU Directive 2002/98/EG and in the Swedish SOSFS 2009:28. The standard blood components are red blood cells, plasma and platelets, while special components such as ir

Chimera states in mechanical oscillator networks

The synchronization of coupled oscillators is a fascinating manifestation of self-organization that nature uses to orchestrate essential processes of life, such as the beating of the heart. Although it was long thought that synchrony and disorder were mutually exclusive steady states for a network of identical oscillators, numerous theoretical studies in recent years have revealed the intriguing p

A Comparison between Indoor and Outdoor Rape Suspects in Sweden

As the number of rapes is increasing in Sweden, and the number of individuals convicted of these crimes is decreasing, it is of importance to study offender characteristics of those committing these crimes and the circumstances in which these crimes are conducted, such as indoors or outdoors. Data from Swedish population-based registers were used to identify individuals suspected of rape, aggravat

Abnormal vital signs are strong predictors for intensive care unit admission and in-hospital mortality in adults triaged in the emergency department-a prospective cohort study

BackgroundAssessment and treatment of the acutely ill patient have improved by introducing systematic assessment and accelerated protocols for specific patient groups. Triage systems are widely used, but few studies have investigated the ability of the triage systems in predicting outcome in the unselected acute population. The aim of this study was to quantify the association between the main com

Machine learning compared with rule-in/rule-out algorithms and logistic regression to predict acute myocardial infarction based on troponin T concentrations

ObjectiveComputerized decision‐support tools may improve diagnosis of acute myocardial infarction (AMI) among patients presenting with chest pain at the emergency department (ED). The primary aim was to assess the predictive accuracy of machine learning algorithms based on paired high‐sensitivity cardiac troponin T (hs‐cTnT) concentrations with varying sampling times, age, and sex in order to rule

A molecular phylogeny of forktail damselflies (genus Ischnura) reveals a dynamic macroevolutionary history of female colour polymorphisms

Colour polymorphisms are popular study systems among biologists interested in evolutionary dynamics, genomics, sexual selection and sexual conflict. In many damselfly groups, such as in the globally distributed genus Ischnura (forktails), sex-limited female colour polymorphisms occur in multiple species. Female-polymorphic species contain two or three female morphs, one of which phenotypically mat

A European Registry Evaluating Symptomatic Effectiveness of Pharmacologically Treated Patients with Lower Urinary Tract Symptoms due to Benign Prostatic Enlargement : Lessons Learned

PURPOSE: We evaluated unmet needs of lower urinary tract symptoms-benign prostatic enlargement pharmacological treatment by measuring symptom improvement, persistence and deterioration in real life. A prospective registry was conducted for 24 months in 5 European countries and analyzed by the European Association of Urology Research Foundation. MATERIALS AND METHODS: Previously untreated and treat

A SET route to Ethyl Carboxylic Acid from Ethanol and Carbon Monoxide

As a hypothetical experiment the reaction between carbon monoxide and ethanol to form an ethyl carboxylic acid has been considered. The SET model for catalysis is used. The effect of the catalyst COS on the reactivity of these two species is found to lead to the expected result.

Cardiac arrest in COVID-19 : characteristics and outcomes of in- and out-of-hospital cardiac arrest. A report from the Swedish Registry for Cardiopulmonary Resuscitation

AIM: To study the characteristics and outcome among cardiac arrest cases with COVID-19 and differences between the pre-pandemic and the pandemic period in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA). METHOD AND RESULTS: We included all patients reported to the Swedish Registry for Cardiopulmonary Resuscitation from 1 January to 20 July 2020. We defined 16 March 2020

Body Temperature and Activity Rhythms Under Different Photoperiods in High Arctic Svalbard ptarmigan (Lagopus muta hyperborea)

Organisms use circadian rhythms to anticipate and exploit daily environmental oscillations. While circadian rhythms are of clear importance for inhabitants of tropic and temperate latitudes, its role for permanent residents of the polar regions is less well understood. The high Arctic Svalbard ptarmigan shows behavioral rhythmicity in presence of light-dark cycles but is arrhythmic during the pola

Moths are strongly attracted to ultraviolet and blue radiation

We carried out three choice experiments with 6116 nocturnal lepidopteran individuals (95 species, 7 families, 32 075 counts), each replicated 105 times during the seasons of 2 years. Moths were released indoors at the centre of a 10 × 10 m area with different lamps placed at each corner. In experiment 1, lamps emitted ultraviolet (UV) (peak at 365 nm), blue (450 nm), green (520 nm) or cool white (

Erövringen : Muslimska brödraskapets infiltration av Sverige

Hur mycket naivitet har präglat svenska politiska partier då de trott att de skulle kunna omvända islamister till demokrater och inkludera dem i det sekulära mångkulturella samhället? Hur mycket naivitet har präglat islamister att tro att de skulle kunna erövra Sverige med infiltration inifrån? Kan islamister förvandlas till demokrater samtidigt som de är textbundna till en fundamentalistisk tolkn

Review: Hansen, E.S. 2020. Bornholms laver [The lichens of Bornholm]

Hansen, E.S. 2020. Bornholms laver [The lichens of Bornholm]. Edited by R. L. Vilsholm, published by NaturBornholm and printed by H. Holm Grafisk ApS, Rønne, ISBN 978-87-91122-30-9, 96 pages.Hansen, E.S. 2020. Bornholms laver [The lichens of Bornholm]. Edited by R. L. Vilsholm, published by NaturBornholm and printed by H. Holm Grafisk ApS, Rønne, ISBN 978-87-91122-30-9, 96 pages.

Untangling the association of amyloid-β and tau with synaptic and axonal loss in Alzheimer's disease

It is currently unclear how amyloid-β and tau deposition are linked to changes in synaptic function and axonal structure over the course of Alzheimer's disease. Here, we assessed these relationships by measuring presynaptic (synaptosomal-associated protein 25, SNAP25; growth-associated protein 43, GAP43), postsynaptic (neurogranin, NRGN) and axonal (neurofilament light chain) markers in the CSF of

Weak Sustainability Trends in the Andean and Nordic Countries: A Historical Perspective

This chapter traces the main sustainability trends of the five countries analyzed in this book. The starting point is to understand sustainability as main measure of development, diminishing the role of GDP or Income. In order to address these concerns the chapter utilizes mainstream indicators such as NaturalResources Intensity and energy consumption, and adding new comprehensive measures of deve

Discourse Analysis —A Critical or Relativistic Perspective in Music Education?

The purpose of this paper is to discuss the problems I have encountered under the development of the theoretical perspective of my thesis. First, discourse analysis is founded in social constructionism and post-structuralistic theory. Second, discourse analysis is a concept including different perspectives, where both more critical approaches with focus on discourses as determining and more relati