Background: The molecular out of Africa hypothesis, OOAH, has been considered as an established fact amid population geneticists for some 25–30 years despite the early concern with it among phylogeneticists with experience beyond that of Homo. The palaeontological support for the hypothesis is also questionable, a circumstance that in the light of expanding Eurasian palaeontological knowledge has

Alzheimer’s disease affects millions of lives worldwide. This terminal disease is characterized by the formation of amyloid aggregates, so-called amyloid oligomers. These oligomers are composed of β-sheet structures, which are believed to be neurotoxic. However, the actual secondary structure that contributes most to neurotoxicity remains unknown. This lack of knowledge is due to the challenging n

The SET theory implies that energy is transferred from the catalyst system via infrared radiation to the molecules that are supposed to react. In previous investigations it has been demonstrated that the activation of the reacting species-as long as the molecules are infrared active-can occur at low adsorption strength. However, for molecules that are IR inactive, e.g. dinitrogen, this is not poss

This study attempts to apply computational methods to the Twitter Election Integrity Datasets in order to derive a basic descriptive overview of this disinformation data, and to suggest some possible routes for developing these methods to address future research questions. The results indicate substantial variations in tweet frequency over time and geographical regions, as well as differences in r

Background: Obesity and associated metabolic conditions impact adipocyte functionality with potential consequences for breast cancer risk and prognosis, but contributing mechanisms remain to be understood. The adipokine receptor adenylyl cyclase-associated protein-1 (CAP1) has been implicated in the progression of breast cancer, but results are conflicting and the underlying molecular mechanisms a

Tanken på ansikte-mot-ansikte-undervisningens överlägsenhet må ha ett starktfäste, men när vi summerar ett år av distansundervisning på universitetsnivå ärdet tydligt att det gått över förväntan.

Contribution to a forum on "Global Eco-Social Policy: Contestation within an Emerging Policy Era?"

Background/Aims Post-filter ionized calcium (iCa) measured on a blood gas analyzer (BGA) during regional citrate anticoagulated continuous renal replacement therapy (CRRT) are needed to control the regime. This increases the workload and requires attention including interpretation of blood analyses. Two algorithms were developed to calculate the post-filter iCa instead. The first algorithm used me

Survival in aquatic environments requires organisms to have effective means of collecting information from their surroundings through various sensing strategies. In this study, we explore how sensing mode and range depend on body size. We find a hierarchy of sensing modes determined by body size. With increasing body size, a larger battery of modes becomes available (chemosensing, mechanosensing,

Introduction: The treatment strategies for a 42-year-old female index patient with moderate Graves’ disease (GD) vary according to several international surveys. The important question whether surveys of treatment preferences in theoretical patient cases also match how real patients are treated has not yet been addressed. Materials and Methods: From a Swedish cohort of 1186 GD patients (TT-12 coho

Predation is a well-studied driver of ecological selection on prey traits, which frequently drives divergence in anti-predator performance across environments that vary in predation risk. However, predation also alters prey mortality regimes, where low predation risk often results in higher prey densities and consequently higher intensities of intraspecific resource competition. In addition, preda

The growing influence of the European Union (EU) on the international political arena and at the same time its “particular kind” of characteristics as an international player appears to be a widely debated issue among various scholars of social sciences over the last decades. During this period a wide range of theories and concepts have attributed various epithets to the EU and tried to explain it

Background: Contamination of drinking water by hazardous chemicals can be associated with human health risks. Recent studies using effect-based in vitro methods have demonstrated that a large part of the observed toxic effects are caused by unknown chemicals. In this study, we have used a panel of effect-based methods to study the presence of chemical contaminants in a unique material; glass-bottl

Background: In childhood cancer care, healthcare professionals must deal with several difficult moral situations in clinical practice. Previous studies show that morally difficult challenges are related to decisions on treatment limitations, infringing on the child's integrity and growing autonomy, and interprofessional conflicts. Research also shows that healthcare professionals have expressed a

I denna AMM-rapport presenteras åtgärdsförslag som syftar till att förbättra skolledares arbetsmiljö. Rapporten är en del av forskningsprojektet ”Skolledares arbetsmiljö: Ett projekt om organisatoriska förutsättningar, stressrelaterad psykisk ohälsa, personalrörlighet och förbättringspotential” som finansierats av AFA Försäkring (dnr 170094). Åtgärdsförslagen har samlats in med hjälp av enkäter, g