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Objectives: Timely discovery and adequate patient management are crucial in non-small cell lung cancer (NSCLC) since long-term survival is only achievable in early-stage disease. In our study, we aimed to elucidate the effects of time to surgery on survival and to assess the impact of the COVID-19 pandemic on elapsed time until surgery. Methods: In total, 2536 Caucasian NSCLC patients who underwen

Phytoglobins (Pgbs) are plant hemoglobin-like proteins with key roles in nitric oxide (NO) scavenging, oxygen sensing, and hypoxic stress responses. Their typical hexacoordination results in unusually high affinities for gaseous ligands such as NO and carbon monoxide (CO), complicating measurement using conventional methods. Standard assays often require large sample volumes and lack sensitivity f

We present time-resolved three-dimensional measurements of the averaged liquid mass distribution generated by the Spray M from the Engine Combustion Network. The operating condition corresponds to a non-reacting early injection case for spray-guided gasoline injection during the first 200 μs. Few-femtosecond X-rays from a compact laser wakefield accelerator, enable quantitative spray measurements,

Differential cross-sections are measured for the production of four charged leptons in association with two jets. These measurements are sensitive to final states in which the jets are produced via the strong interaction as well as to the purely-electroweak vector boson scattering process. The analysis is performed using proton-proton collision data collected by ATLAS at s = 13 TeV and with an int

Two-dimensional terahertz spectroscopy (2DTS) is a low-frequency analog of two-dimensional optical spectroscopy that is rapidly maturing as a probe of a wide variety of condensed matter systems. However, a persistent problem with 2DTS is the long experimental acquisition times, which prevent its broader adoption. A potential solution, requiring no increase in experimental complexity, is signal rec

Balancing selection is a potentially important factor in the maintenance of genetic variation for fitness and, alongside recessive deleterious mutations, the genetic basis of inbreeding depression. Classic population genetics theory predicts that inbreeding restricts the range of conditions leading to balancing selection. For example, in models of heterozygote advantage, the classic theory shows t

I uppsatsen undersöker vi hur ett system styrt av Klein-Gordon-ekvationen beter sig under en punktpåverkan. Detta är den enklaste typen av påverkan och med hjälp av denna kunskap kan man dra slutsatser om systemets beteende för mer generalla fall av påverkan. Kvantfysiken beskriver de mest fundamentala byggstenarna av vårt universum, subatomära partiklar. Dessa är, som namnet tyder på, mindre än This paper explores the Klein-Gordon equation, a relativistic wave equation. More specifically, it studies the free form of the equation, where the potential is set to zero. The partial differential equation, together with initial conditions, forms an initial value problem. The first goal of the paper is to derive the Green's function for the problem. This is done in several ways, using spectr

The European Union's climate strategy emphasises energy democracy, encouraging citizens to participate actively in energy production and consumption as part of the transition to climate neutrality by 2050. This chapter explores the role of energy communities (ECs) in advancing energy democracy, particularly within Sweden's centralised energy system. ECs offer citizens a pathway to collective owner

Supplemental Instruction has worked very well in various settings all over the world. It should be of interest to see if SI works at earlier stages than tertiary education. There are examples of successful SI programs at upper secondary schools, but no reports from lower secondary schools. This study evaluates a pilot SI program in a 7th and a 9th grade class in a socially challenged area with reg

Denna avhandling undersöker hur legitimiteten i Europeiska Unionens (EU) stöd för LGBTIQ-jämlikhet bör bedömas och hävdas mot bakgrund av ytterhögerns främjande av en konkurrerande vision för europeiskt samarbete som är rotad i anti-genderpolitik. Med utgångspunkt i agonistisk och queer-teori konceptualiseras EU:s stöd för LGBTIQ-jämlikhet som ett försök att skapa en europeisk pro-LGBTIQ-konsensusThis dissertation examines how the legitimacy of the European Union’s (EU) support for LGBTIQ equality should be assessed and asserted amid the far right’s promotion of a rival vision for European cooperation rooted in anti-gender politics. Drawing on agonistic and queer theory, the EU’s support for LGBTIQ equality is conceptualised as an effort to forge a European pro-LGBTIQ consensus, termed sex

Översiktsverk över de svenska akademiska högtidernas allmänna historia respektive nuvarande utformning vid Sveriges olika universitet och högskolor.

Pediatric randomized controlled trials (RCTs) inform decisions concerning the choice of interventions in children and adolescents. To enable the implementation of effective interventions, RCT reports need to provide adequate details on the elements, infrastructure, and delivery of these interventions. Using the 12-item Template for the Intervention Description and Replication (TIDieR) framework, a

INTRODUCTION: Patients with non-small cell lung cancer (NSCLC) faced an elevated risk for severe COVID-19 outcomes and were prioritized for early vaccination. However, immune responses to SARS-CoV-2 vaccines remain poorly characterized in this group, especially in patients receiving immune checkpoint inhibitor PD-1/PDL-1 (ICI) therapy.MATERIALS AND METHODS: In this prospective observational study,

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia and is associated with increased risk of stroke, heart failure, and mortality. One of the systems which AF is influenced by is the autonomic nervous system (ANS), which regulates involuntary functions such as heart rate. Environmental stressors, such as air pollution, may also affect these physiological systems and contribute

The Kunming-Montréal Global Biodiversity Framework, adopted at COP15, establishes a clear mandate to mobilize funding from diverse sources to address the escalating biodiversity crisis. Despite growing awareness and commitment to biodiversity conservation, a substantial financing gap persists, hindering efforts to protect and restore ecosystems effectively. This chapter provides an in-depth examin